investigationalantimicrobialagentsof2013(新鲜出

  10.1128/CMR.00033-13.2013,26(4):792.DOI:Clin.Microbiol.Rev. MichaelJ.PucciandKarenBush 2013InvestigationalAntimicrobialAgentsofhttp://cmr.asm.org/content/26/4/792Updatedinformationandservicescanbefoundat:Theseinclude:REFERENCEShttp://cmr.asm.org/content/26/4/792#ref-list-1freeat:Thisarticlecites211articles,118ofwhichcanbeaccessedCONTENTALERTSmore»articlescitethisarticle),Receive:RSSFeeds,eTOCs,freeemailalerts(whennewhttp://journals.asm.org/site/misc/reprints.xhtmlInformationaboutcommercialreprintorders:http://journals.asm.org/site/subscriptions/TosubscribetotoanotherASMJournalgoto:onOctober8,2013byMERCK&COINChttp://cmr.asm.org/DownloadedfromonOctober8,2013byMERCK&COINChttp://cmr.asm.org/DownloadedfromonOctober8,2013byMERCK&COINChttp://cmr.asm.org/DownloadedfromonOctober8,2013byMERCK&COINChttp://cmr.asm.org/DownloadedfromonOctober8,2013byMERCK&COINChttp://cmr.asm.org/DownloadedfromonOctober8,2013byMERCK&COINChttp://cmr.asm.org/DownloadedfromonOctober8,2013byMERCK&COINChttp://cmr.asm.org/DownloadedfromonOctober8,2013byMERCK&COINChttp://cmr.asm.org/DownloadedfromonOctober8,2013byMERCK&COINChttp://cmr.asm.org/DownloadedfromonOctober8,2013byMERCK&COINChttp://cmr.asm.org/DownloadedfromonOctober8,2013byMERCK&COINChttp://cmr.asm.org/DownloadedfromonOctober8,2013byMERCK&COINChttp://cmr.asm.org/DownloadedfromonOctober8,2013byMERCK&COINChttp://cmr.asm.org/DownloadedfromonOctober8,2013byMERCK&COINChttp://cmr.asm.org/DownloadedfromonOctober8,2013byMERCK&COINChttp://cmr.asm.org/DownloadedfromonOctober8,2013byMERCK&COINChttp://cmr.asm.org/DownloadedfromonOctober8,2013byMERCK&COINChttp://cmr.asm.org/DownloadedfromonOctober8,2013byMERCK&COINChttp://cmr.asm.org/DownloadedfromonOctober8,2013byMERCK&COINChttp://cmr.asm.org/DownloadedfromonOctober8,2013byMERCK&COINChttp://cmr.asm.org/DownloadedfromonOctober8,2013byMERCK&COINChttp://cmr.asm.org/DownloadedfromonOctober8,2013byMERCK&COINChttp://cmr.asm.org/DownloadedfromonOctober8,2013byMERCK&COINChttp://cmr.asm.org/DownloadedfromonOctober8,2013byMERCK&COINChttp://cmr.asm.org/DownloadedfromonOctober8,2013byMERCK&COINChttp://cmr.asm.org/DownloadedfromonOctober8,2013byMERCK&COINChttp://cmr.asm.org/DownloadedfromonOctober8,2013byMERCK&COINChttp://cmr.asm.org/DownloadedfromonOctober8,2013byMERCK&COINChttp://cmr.asm.org/DownloadedfromonOctober8,2013byMERCK&COINChttp://cmr.asm.org/DownloadedfromonOctober8,2013byMERCK&COINChttp://cmr.asm.org/DownloadedfromonOctober8,2013byMERCK&COINChttp://cmr.asm.org/DownloadedfromInvestigationalAntimicrobialAgentsof2013MichaelJ.Pucci,aKarenBushbAchillionPharmaceuticals,NewHaven,Connecticut,USAa;IndianaUniversity,Bloomington,Indiana,USAbSUMMARY..................................................................................................................................................793INTRODUCTION............................................................................................................................................793DNATOPOISOMERASEINHIBITORS.......................................................................................................................794Quinolones...............................................................................................................................................794Nemonoxacin..........................................................................................................................................794Delafloxacin............................................................................................................................................794Finafloxacin............................................................................................................................................795Zabofloxacin...........................................................................................................................................796JNJ-Q2.................................................................................................................................................796DS-8587................................................................................................................................................796KPI-10..................................................................................................................................................796Ozenoxacin............................................................................................................................................796Chinfloxacin...........................................................................................................................................797GSK2140944...........................................................................................................................................797ACH-702...............................................................................................................................................797PROTEINSYNTHESISINHIBITORS................................