MARKETRESEARCHREPORTC$RDIOVASCULARTHERAPEUTICDRUGS:TECHNOLOGIESANDGLOBALMARKETSPHM024BJacksonHighsmithProjectAnalystBCCResearch35WalnutStreetWellesley,MA02481Phone:866-285-7215(sales)WebAddress:@bccresearch.comISBN:1-59623-618-3PHM024B—CardiovascularTherapeuticDrugs:TechnologiesandGlobalMarketsTABLEOFCONTENTSCopyright©BCCResearch,Wellesley,MAUSA,Web:’sinformationproductsexploremajormarket,economic,scientific,andtechnologicaldevelopmentsforbusinessleadersinindustrial,pharmaceutical,andhightechnologyorganizations.Industryanalysisandmarketforecastsforadvancedmaterials,high-techsystemsandcomponents,nanotechnologyandnovelprocessingmethodsareattheforefrontofthecompany’sexpertise.Formorethan35years,BCC’smarketanalysishasprovidedbusinesseswiththeinsightneededtomakeintelligentandstrategicbusinessdecisions.BCCResearchisaunitofEliResearch,whichisbasedinDurham,N.C.CONDITIONSOFPURCHASEThepurchaseoftheboundorelectroniccopyofthisreportconstitutesacontractualagreementbetweenBCCResearchandthepurchaser.Thisreportisintendedforusesolelybythepersonwhomadethepurchase.Thereportanditscontentsarenottobemadeavailabletootherpersons,autonomousdivisions,foreignsubsidiariesofthesamecompany,orothercompanies.Reproductionofanymaterialinthisreportisstrictlyforbiddenwithoutwrittenpermissionofthepublisher.Inturn,BCCResearchwillregardtheidentityofthereport’spurchaserasconfidential.ADDITIONALCOPIESAdditionalboundcopiesofthisreport,intendedforusebytheoperatingdivisionforwhichthefirstcopyispurchased,maybeobtainedfromBCCatdiscountedprices.Additionalboundcopypricesdonotapplytoreportspurchasedforuseatseparatelocations.Licensesforuseofelectroniccopiesbyadditionalpersonsorlocationsareavailable.PleasecallBCCforpricing.CUSTOMANALYSESBCCprovidescustomresearchstudiestailoredtoourclients’needsinareasrelatedtothesubjectresearchmaterial,butperhapsnotcoveredindetailinthisreport.PleasecontactBCCregardingthetermsandconditionsofsuchservices.DISCLAIMERThispublicationprovidesinformativematerialofaprofessionalnature.Itdoesnotconstitutemanagerial,legaloraccountingadvice,norshoulditserveasacorporatepolicyguide,laboratorymanualoranendorsementofanyproduct.Thisinformationisintendedtobeasaccurateaspossibleatthetimeofpublication,butBCCInc.assumesnoresponsibilityforanylossesordamagesthatmightresultbecauseofrelianceonthismaterial.¤Copyright2010byBCCResearchWellesley,MA02481ReproductionofanymaterialinthisreportisstrictlyforbiddenwithoutexpresspermissionofthePublisher.ToreceiveacompletecatalogofBCCstudies,pleasevisitourWebsiteat—CardiovascularTherapeuticDrugs:TechnologiesandGlobalMarketsTABLEOFCONTENTSCopyright©BCCResearch,Wellesley,MAUSA,Web::SUMMARY......................................................................................6SUMMARYTABLEGLOBALCARDIOVASCULARFORECASTBYDISEASECLASS,THROUGH2015($MILLIONS)........................................6SUMMARYFIGUREGLOBALCARDIOVASCULARFORECASTBYDISEASECLASS,2007-2015($MILLIONS)...................................................7SUMMARY(CONTINUED)...............................................................................8CHAPTERTHREE:OVERVIEW................................................................................9CURRENTSTATEOFCARDIOVASCULARDISEASE..................................9FIGURE1LEADINGCAUSESOFDEATHINTHEUNITEDSTATES;2006(DEATHSPER100,000).............................................................................9FIGURE1(CONTINUED).....................................................................................10ESTABLISHEDDRUGCLASSESINCARDIOVASCULARDISEASE...........................................................................................11Statins..........................................................................................11AngiotensinReceptorBlocker.....................................................11AngiotensinConvertingEnzyme(ACE)inhibitors....................12EMERGINGDRUGCLASSES.......