全二维气相色谱技术及其进展

:2000204218:(19632),,,,:[phone],E2mail:[e-mail],,,,(,116011):,,,,(GCGC)GCGC,GCGC3GCGCGCGC:;;;;:O658:A:100028713(2001)02201322051,,,,[1](comprehensivetwo2dimensionalgaschromato2graphy,GCGC),(GC+GC)GC+GC,1,2;,12,,,,12,(GCGC)[2,3],1,,22,1,2,,[4]2090,,2,,,2090,Jorgen2son[5]19902,,Phillips[2,6],1,2,1,2[7],,1,21,1Phillips1991GCGC,19220013CHINESEJOURNALOFCHROMATOGRAPHYVol.19No.2March2001©1995-2006TsinghuaTongfangOpticalDiscCo.,Ltd.Allrightsreserved.,PhillipsZoex1999:(1),SouthernIllinois1[8](2)2050[9,10](3),(4)31,,2,(1)3,,(5),(ASTM),ASTM(BTEX),3,1GCGCASTM,(MTBE)1GCGCFig.1GCGCchromatogramofgasoilThechromatogramexhibitsabout2000peaksarrangedinbandsofcompoundclasses,andsub2bandsofstructuralisomers.Theorderlypeakarrangementsimplifiesinterpretation.Onlytwocolumnsofonemeterlengthwereusedinthisanalysis,whichlasted60minutes.Column1:1m0.1mm3.0m00721,modulator0.1m0.1mm3.0m00721,column2:1.0m0.1mm0.1m00721701.Columntemperature:35,5min,at5/minto250.ThechromatogramisfromShellInternationalChemicals,Thornton,UK.,GCGC(),3GCGC3.1GCGC,1,221,112:(1)1;(2)2,;(3),,(1)[11]:a.2;b.,12,3312:©1995-2006TsinghuaTongfangOpticalDiscCo.,Ltd.Allrightsreserved.GCGC,(2),Phillips[12,13],1[14],,[7]deGeus,[15,16],LedfordPhillips[7](),:,,100[1720],(LMCS)1,,T()R()R,,,2,1,2(),,1[18,19],:-503.2,1,,,2OV21701,BPX503.3GCGC,GCGC,,,2,60ms[16]2100ms200ms,,100Hz,GCGCFID,,FID,ECD[15],GCGCGCGC,(TOF2MS)(100/s),GCGC2TOF2MS4,GCGC,,100,GCGCGC30100,GCGC,4.1,24C10C25(),4107[21],,GC,Blomberg[4,9,16,22,23]GCGC,1,,Frysinger[24](BTEX),GCGC[25]GCGCGaines[26]Xu[8]GCGC2,1Synovec[11]GCGC,2,(GRAM)Kinghorn[18][19],43119©1995-2006TsinghuaTongfangOpticalDiscCo.,Ltd.Allrightsreserved.4.2,,,(PCBs)PCBs209,150[27]1977PCBs,PCBsPCB,,,,,PCBs[28]deGeus[15]2GCGCCBs77,126169PCBAroclor1254,,2[29]Xu[8,30],PCBsGCGC,,197,,GCGC,Liu[31]GCGC,GCGC,,Gaines[32]GCGC,GCGC[26]4.3,GCGC,:((PCBs)(PBDEsPBBs)),(PCAs),(PCNs),(),,((PCTs)),,GCGC,,GCGC,[32]GCGC,,(Zoex),,GCGC,GCGC()GCGC,TOF2MSGCGC,GCGC:[1]SchomburgG.JChromatogrA,1995,703:3092325[2]LiuZ,PhillipsJB.JChromatogrSci,1991,29:2272231[3]VenkatramaniCJ,XuJ,PhillipsJB.AnalChem,1996,68:148621492[4]BlombergJ,SchoenmakersPJ,BeensJ,etal.JHRC&CC,1997,20:5392544[5]BusheyMM,JorgensonJW.AnalChem,1990,62:1612167[6]PhillipsJB,LuuD,PawliszynJB,etal.AnalChem,1985,57:277922787[7]PhillipsJB,GainesRB,BlombergJ,etal.JHRC&CC,1999,22:3210[8]XuJ.[PhDThesis].Illinois:SouthernIllinoisUniversi2ty,1997[9]BeensJ,BoelensH,TijssenR,etal.JHRC&CC,1998,21:47254[10]deGeusH,deBoerJ,PhillipsJB,etal.JHRC&CC,1998,21:4112413[11]BrucknerCA,PrazenBJ,SynovecRE.AnalChem,1998,70(14):279622804[12]PhillipsJB,LiuZ.USP5196039.1993[13]PhillipsJB,LiuZ.USP5135549.1992[14]PhillipsJB,XuJ.JChromtogrA,1995,703:3272334[15]deGeusH,deBoerJ,BrinkmanUAT.JChromatogrA,1997,767:1372151[16]BeensJ,BlombergJ,TijssenR.JChromatogrA,1998,882:2332251[17]MarriottPJ,KinghornRM.AnalChem,1997,69(13):2582225885312:©1995-2006TsinghuaTongfangOpticalDiscCo.,Ltd.Allrightsreserved.[18]KinghornRM,MarriottPJ.JHRC&CC,1998,21:6202622[19]KinghornRM,MarriottPJ.JHRC&CC,1999,22:2352238[20]KinghornRM,MarriottPJ.JHRC&CC,1998,32238[21]NeumannHJ,Paczynska2LahmeB,SeverinD.Com2positionalpropertiesofpetroleum.Stuttgart(Germany):FerdinandEnkePubl,1981[22]BeensJ.[PhDThesis].Eindhaven:UniversityofAms2terdam,1998[23]BeensJ,TijssenR,BlombergJ.JHRC&CC,1998,21:63265[24]FrysingerGS,GainesRB,LedfordEBJr.JHRC&CC,1999,22:1952200[25]FrysingerGS,GainesRB.JHRC&CC,1999,22:2512255[26]GainesRB,FrysingerGS,Hendrick2SmithMS,etal.EnvironSciTechnol,1999,33:210622108[27]FrameG.AnalChem,1997,69:468A2475A[28]FrameGM,FreseniusZ.AnalChem,1997,357:7012713[29]deGeusHJ,deBoerJ,BrinkmanUAT.TRAC,1996,5:3982408[30]PhillipsJB,XuJ.OrganohalogenCompounds,1997,31:1992201[31]LiuZ,SirimanneSR,PattersonDGJr,etal.AnalChem,1994,66:308623092[32]GainesRB,LedfordEBJr,StuartJD.JMicrocolSep,1998,10:5972600TechniqueandAdvanceofComprehensiveTwo2DimensionalGasChromatographyXUGuo2wang,YEFen,KONGHong2wei,LUXin,ZHAOXin2jie(NationalChromatographicR.&A.Center,DalianInstituteofChemicalPhysics,TheChineseAcademyofSciences,Dalian116011,China)Abstract:Manyanalyticalproblemsrequiremoreresolutionthantheconventionalsinglecolumnchromatographictechniquecanprovide.Insuchcasestheseparationpowercanbeenhancedbyusingmorethanoneseparationtechniqueormechanism.Thesampleisthendispersedindifferenttimedimensions.Theresolutionobtaineddependsstronglyonthedifferencebetweenthesedimensions.Thehighestresolutionisgainedwhenthereisnocorrelationbetweentheseparations,thedimensionsbeingorthogonaltoeachother.Comprehensivetwo2dimensionalgaschromatography(GCGC)providesatrueorthogonalseparationsysteminwhichamodulatorseriallycouplestwocolumnscontainingdissimilarstationaryphases.Itfocusesandsubsequentlyreinjectscomponentselutingfromthefirstcolumnintothesecondone.Thesystemgeneratesapeakcapacitythatisapproximatelyequaltotheproductofthepeakcapacitiesofthetwoindividualseparationsystems.Inthispaper,techniqueandinstrumentalconsiderationsofGCGCarediscussed.ThethreedesignsofcontemporaryGCGCsystemsarepresentedandcompared.Anum