mTOR信号通路与细胞生长调控

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mTOR信号通路与细胞生长调控作者:王志钢,吴应积,旭日干,WANGZhi-Gang,WUYing-Ji,Shorgen作者单位:内蒙古大学生命科学学院,哺乳动物生殖生物学与生物技术教育部重点实验室,呼和浩特010021刊名:生物物理学报英文刊名:ACTABIOPHYSICASINICA年,卷(期):2007,23(5)被引用次数:8次参考文献(33条)1.SchmelzleT;HallMNTOR,acentralcontrollerofcellgrowth[外文期刊]2000(2)2.HayN;SonenbergNUpstreamanddownstreamofmTOR[外文期刊]20043.WullschlegerS;LoewithR;HallMNTORsignalingingrowthandmetabolism[外文期刊]20064.LoewithR;JacintoE;WullschlegerS;LorbergACrespoJLBonenfantDOppligerWJenoePHallMNTwoTORcomplexes,onlyoneofwhichisrapamycinsemitive,havedistinctrolesincellgrowthcontrol[外文期刊]2002(3)5.HansenIA;AttardoGM;ParkJH;PongQRaikhelASTargetofrapamycin-mediatedaminoacidsignalinginmosquitoanautogeny[外文期刊]2004(29)6.LiY;CorradettiMN;InokiK;GuanKLTSC2:fillingtheGAPinthemTORsignalingpathway[外文期刊]2004(01)7.ShawRJ;CantleyLCRas,P13KandmTORsignallingcontrolstumourcellgrowth[外文期刊]2006(7092)8.HaraK;MarukiY;LongX;YoshinoKOshiroN,HidayatS,TokunagaC,AvruchJ,YonezawaKRaptorabindingpartneroftargetofRapamycin(TOR),mediatesTORaction[外文期刊]20029.SarbasaovDD;AliSM;KimDH;GuertinDALatekRRErdjument-BromageHTempstPSabatiniDMRietor,anovelbindingpartnerofmTOR,definesarapamycininsensitiveandraptor-independentpathwaythatregulatesthecytoskeleton200410.ChenEJ;KaiserCALST8negativelyregulatesaminoacidbiosynthesisasacomponentoftheTORpathway2003(02)11.KimDH;SarbassovDD;AliSM;LatekRR,GunturKV,Erdjument-BromageH,TempstP,SabatiniDMGBL,apositiveregulatoroftheRapamycin-sensitivepathwayrequiredforthenutrient-sensitiveinteractionbetweenraptorandmTOR200312.FingarDC;RichardsonCJ;TeeAR;CheathamLTsouCBlenisJmTORcontrolscellcycleprogressionthroughitscellgrowtheffectorsS6K1and4E-BP1/EukaryoticWanslationinitiationfactor4E[外文期刊]2004(01)13.ProudCGRegulationofmammaliantranslationfactorsbynutrients[外文期刊]200214.EguchiS;TokunagaC;HidaymS;OshiroN,YoshinoK,KikkawaU.YonezawaKDifferentrolesfortheTOSandRAIPmotifsofthetranslationregulatorprotein4E-BP1intheassociationwithraptorandphosphorylationbymTORintheregulationofcellsize[外文期刊]2006(7)15.PhinS;KupferwasserD;LainJLee-FrumanKICMutationalanalysisofribosomalS6kinase2showsdifferentialregulationofitskinaseactivityfromthatofribosomalS6kinase1[外文期刊]2003(Pt.2)16.RebholzH;PanasyukG;FentonT;NernaranyyLValovkaTFlajoletMRonnsuandLStephensLWestAGoutITReceptorassociationandtyrosinephosphorylationofS6kinases[外文期刊]2006(9)17.PendeM;UmSH;MieuletV;StickerM,GossVL,MestanJ,MuellerM,FumagalliS,KozmaSC,ThomasGS6K1-/-/S6K2-/-miceexhibitperinatallethalityandrapamycinsensitive5'-terminaloligopyriraidinemRNAtranslationandrevealamitogan-activatedproteinkinase-dependentS6kinasepathway[外文期刊]2004(08)18.MaL;ChenZ;Erdjument-BromageH;TernpstPPandolfiPPPhosphorylationandfunctionalinactivationofTSC2byErkimplicationsfortuberoussclerosisandcancerpathogenesis[外文期刊]2005(02)19.RouxPP;BallifBA;AnjumR;GygiSPBlenisJTumor-promotingphorbolestersandactivatedRasinactivatethemberoussclerosistumorsuppressorcomplexviap90ribosomalS6kinase2004(37)20.AvruchJ;HamK;LinY;LiuMLongXOrtiz-VegaSYonezawaKInsulinandamino-acidregulationofmTORsignalingandkinaseactivitythroughtheRhebGTPase[外文期刊]2006(48)21.SmithEM;FinnSG;TeeAR;BrowneGJ,ProudCGThetuberoussclerosisproteinTSC2isnotrequiredfortheregulationofthemammaliantargetofrapamycinbyaminoacidsandcellularstresses[外文期刊]2005(19)22.WangX;BeugnetA;MurakamiM;YamanakaSProudCGDistinctsignalingeventsdownstreamofmTORcooperatetomediatetheeffectsofgminoacidsandinsulinoninitiationfactor4E-bindingproteins[外文期刊]2005(07)23.sbahOJ;HunterTTurnoveroftheactivefractionofIRSIinvolvesraptor-mTOR-andS6K1-dcpendentserinephosphorylationincellculturemodelsoftuberoussclerosis[外文期刊]2006(17)24.GaoN;FlyrmDC;ZhangZ;ZhongXSWalkerVLiuKJShiXJiangBHG1cellcycleprogressionandtheexpressionofG1cyclinsareregulatedbyP13K/AKT/mTOR/p70S6K1signalinginhumanovariancancercells[外文期刊]2004(02)25.EguchiS;TokunagaC;HidayatS;OshiroN,YoshinoKKikkawaU.YonezawaKDifferentrolesfortheTOSandRAIPmotifsofthetranslmionalregulatorprotein4E-BP1intheassociationwithraptorandphosphorylationbymTORintheregulationofcellsize[外文期刊]2006(07)26.LiuL;CashTP;JonesRG;KeithBThompsonCBSimonMCHypoxia-inducedenergystressregulatesmRNAtranslationandcellgrowth[外文期刊]2006(04)27.JanklewiczM;gronerB;DesrivieresSMammaliantargetofrapamycinregulatesthegrowthofmammaryepithelialcellsthroughtheinhibitorofdeoxyribonucleicacidbindingId1andtheirfunctionaldifferentiationthroughId2[外文期刊]2006(10)28.GangloffYG;MuellerM;DaunSG;SvobodaPStickerMSpetzJFUmSHBrownEJCereghiniSThomasGKozmaSCDisruptionofthemousemTORgeneleadstoearlyposfimplantationlethalityandprohibitsembryonicstemcelldevelopment[外文期刊]2004(21)29.MurakamiM;IchisakaT;MaedaM;OshiroN,HaraK,EdenhoferF,KiyamaH,YonezawaK,YamanakaSmTORisessentialforgrowthandproliferationinearlymouseembryosandembryonicstemcells30.SabatiniDMmTORandcancer:insightsintoacomplexrelationship[外文期刊]2006(09)31.IeoneM;CrowellKJ;ChenJ;JungDChiangGGSarethSAbrahamRTPellecchiaMTheFRBdomainofmTOR:NMRsolutionstructureandinhibitordesign[外文期刊]2006(34)32.UmSH;D'AlessioD;ThomasGNutrientoverlaod,insulinresistance,andribosomalproteinS6kinase1,S6K1[外文期刊]2006(06)33.CotaD;P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