搜索
放射动力治疗肿瘤病例RadiodynamictherapycausedearlyresponseoftumorsAclinicalcasereportHighenergyX-rayWaterirradiationPhotoactivedrugirradiationPorphyrinssubstrate1O2.OH+RDTRadiodynamictherapy1O220nmRadiotherapyRadio-dynamictherapy(moleculartarget)BeforetreatmentAftertreatment(3times)RabbitVX2carcinomaBeforetreatment3daysaftertreatment(once)Thyreoidcarcinomawithmetastasisinlymphnodesofhead/neckandsubaxillary18F-FDGPETimagingRDTaloneRDT+RT(8Gy)RDTaloneRDT+RT(8Gy)Beforetreatment4daysAftertreatment(once)Parotidcarcinoma(squamouscarcinoma)withmetastasisinliverandleftlung18F-FDGPETimagingRDT+RT(6Gy)RDT+RT(6Gy)RDTaloneRDTaloneTherapeuticprotocolHighenergyX-rayexposureafter4-6hoursaccumulationofpPIXintumors(oraladministrationof5-aminolaevulinicacid)TheX-raydoseof2-4GywasusedforpPIXexcitingtoinducethefinalproductofsingletoxygenTreatmentwasgivenonceortwicewasperweekwithtotal4-6timesHeadandneckcancerCarcinomaofparotidgland,recurrenceaftersurgeryBeforetreatmentaftertreatment(4days)Carcinomaofparotidgland,recurrenceaftersurgeryBeforetreatmentaftertreatment(4days)tonguecancerwithlungmetastasisBeforetreatmentaftertreatment(4days)Beforetreatmentaftertreatment(4days)Reduced63%LungcancerLeftlungcancer(adenocarcinoma)Beforechemotherapy5daysafterchemotherapy3daysafterRDTBeforetreatmentaftertreatment(3days)Leftlungcancer(adenocarcinoma)23.4%Reduce23.4%Beforetreatmentaftertreatment(3days)aftertreatment(8weeks)Reduce23.4%50%Beforetreatmentaftertreatment(8weeks)Leftlungcancer(adenocarcinoma)OneweekafterchemotherapyfirstRDTsecondRDT(4days)Leftlungcancer(squamouscarcinoma)Beforetreatmentaftertreatment(3months)Leftlungcancer,Reduced56%.RadiationinflammationafterRDTLeftlungcancer(smallcell)withmetastasisoflymphnodesinthemediastinumandhilumBeforetreatmentaftertreatment(4days)Beforetreatmentaftertreatment(5days)Lungcancerwithmetastasisoflymphnodes.Reduced81%Beforetreatmentaftertreatment(5days)Lungcancerwithmetastasisoflymphnodes.Reduced83%BreastcancerBeforetreatmentAftertreatment(4sdays)Rightbreastcancer,recurrence2yaftersurgerywithinvasionofmediastinumlymphnodesandmetastasisinliverBeforetreatmentaftertreatment(4days)Reduced23%Beforetreatmentaftertreatment(4days)Reduced43%EsophagealcancerEsophagealcancer,recurrence1yaftersurgerywithmetastasislesionsinrightlung,mediastinumlymphnodesandlefthumerusbone.Beforetreatmentaftertreatment(4days)Aftertreatment(6weeks)Beforetreatmentaftertreatment(4days)Reduced36%Reduced76%Beforetreatmentaftertreatment(4days)Aftertreatment(6weeks)BeforetreatmentaftertreatmentEsophagealcancer,recurrenceaftersurgeryBeforetreatmentaftertreatmentEsophagealcancer,recurrenceaftersurgeryHepaticcarcinoma(HCC)HCCHCC,reduced68%Beforetreatmentaftertreatment(4days)RightlobeHCCafter2ysurgeryofLeftlobeHCCGallbladdercancerGallbladdercancerwithinvasionofliverandretroperitoneallymphnodesBeforetreatmentaftertreatment(4days)Beforetreatmentaftertreatment(4days)Gallbladdercancerwithmetastasisoflymphnode,reduced65%Beforetreatmentaftertreatment(4days)Gallbladdercancerwithmetastasisoflymphnode,reduced54%LymphomaLymphoma(largeB-cell)andcoloncancerBeforetreatmentaftertreatment(4days)RightcolonRightcolonBeforetreatmentaftertreatment(4days)Supraclavicularnodes.Reduced80%ColoncancerColoncancerwithinvasionofperitoneallymphnodes,retroperitoneallymphnodes,andsupraclavicularnodes.Leftiliacbonemetastasis.Beforetreatmentaftertreatment(4days)Beforetreatmentaftertreatment(4days)Reduced34%ofsupraclavicularnodeBeforetreatmentaftertreatment(4days)Reduced21%ofperitoneallymphnodes