病例交叉研究

Case-crossoverstudyHUYi2songAR181.2100826013(2001)0420341203,(),,Maclure1991(case2crossoverstudy),11.1,,1.2(delay)ö(carryover),,,30min,30min,()1.3,,,,(2000J1113)(:98437231),230032(1977-),,,,,,,,22.1,,;,,,,,,,,2.2,,,,,,,,()2.3,,,,,33.1(unidirectionalcase-crossoverdesign)14320011254,,,,3.2(bidirectionalcase-crossoverdesign)Greeland(1996),,,,,,,,,(),,,,,,:11:,(1h)11,Mantel2Haenszellogistic1M:(1,25),1M,logistic:,,,,,,Mantel2Haenszel44.1,4.2,,1h4.3,,,1M,Mittleman(1994)111M,11RR95%2.7,1M,RR,,95%,1114%,,,,,logistic,,,,,,4.4,,4.5,,26h,,4.64.754.855.11111,,1:243ChinJDisControlPrev2001Dec;5(4)111abcdOR=böc5.25.2.1(concurrenceobservedodds)(ab),,10,015.2.2(concurrenceexpectedodds),,,x,y,xy,,,1h,2,(x):2521=104(h),(y):24365-x=8656(h)5.2.3RR=2aiyi2bixi,10yi,01xi2RR:2(ab)(xy)110102020182230152541011195011218RR=(20+19)ö(8+5+12)=1.565.3,logistic,logistic,SASSPSSBMDP6()6.1,;,;,();,;;,6.2,,,;,,6.3(),,,,,,logistic7Mittleman1994:7.1(),7.21228,4d,26h(11)(6)7.34.4%11,,RR5.6(95%CI:2.712.8):RR5.9(95%CI:4.67.7)112345RR107(95%CI:67171)19.4(95%CI:9.938.1)8.6(95%CI:3.620.5)2.4(95%CI:1.53.7),,1h,7.4,(2001208211)34320011254