CHINATROPICALMEDICINEVol.10No.6June20102010106,、,。、,、,。、、[1]。FUO。1338.3℃≥1、[1]。38.3℃ESRC[234]。1998FUO2~3≥38.5℃、[5]。2[6]:、。2.1。、、、。2.2-。2.3。、、50%~70%。318%~42%[78]。。AduanRP347654%[9]。DanielC199561%[10]。19915~20085247FUO38。1016553322l1[11]。4。。。EP。1ET。2EPEP。、。-1IL-1IL-1IL-1ra、-αTNF-α、-6IL-6、IFN-α。、、。、、。。Still12。。。R441.3B1009-972720106-710-031.20085150002.518036Discussiononfeversofunkowncauses.OUPeng-chengPENGYan-zhong.PostgraduateShantouUniversityMedicalCollegeShantou515000GuangdongP.R.China7102010106CHINATROPICALMEDICINEVol.10No.6June2010。5:37.3~38℃38.1~39℃39.1~41℃41℃。66.1。、、、、、、、。。5d,VAP7d,5~7d。6.2。、、、、、,、、。6.36.3.1—、、、,、、。6.3.2、、、、。6.3.3C—、、、,C—。6.3.4γ—、。、、。6.3.5。6.3.6HIV、EB。、。6.3.7。6.4XCT、、MRI、、。1818F-FDGPET—PET/CTFUO[12]。6.5、、、、,。6.6。6.6.1,。6.6.2,,。6.6.3。6.6.4、。6.6.5+。6.6.6,。7、、,。7.1。8%~20%FUO。、[13]。7.2HIV、、。。48~72h。、FUO。1.J.200815105~6.2PetersdorfRBBeesonPB.Feverofunexplainedorigin:reporton100casesJ.Medicine1961401~30.3KnockaertDCVanderschuerenSBlockmansD.Feverofunknownorigininadults40yearsonJ.JInternMed20032533263~275.4BryanCS.FeverofunknownorigintheevolvingdefinitionJ.ArchInternMed200316391003~1004.5.J.1999385784~785.6.J.,200416435~437.711CHINATROPICALMEDICINEVol.10No.6June201020101067Bleeker-RoversCPBosFJdeKleijnEMetal.AprospectivemulticenterstudyonfeverofunknownorigintheyieldofastructureddiagnosticprotocolJ.Medicine200786126~38.8KnockaertDC.Recurrentfeverofunknownorigin.InCunhaBAeditor.FeverofunknownoriginM.NewYorkInformationhealthcare2007p133~149.9AduanRPFauciASDaleDCetal.ProlongedfeverofunknownoriginFUOaprospectivestudyof347patientsJ.ClinicalResearch197826558A.10DanielC.KnockaertKarlS.DujardinHermanJ.Bobbaers.Long-termFollow-upofPatientsWithUndiagnosedFeverofUnknownOriginJ.ArchInternMed1996156618~620.11.38J.20093135~7.12ZoharKeidarAlexandraGurman-BalbirDianaGaitinietal.FeverofunknownoriginTheroleof18F-FDGPET/CTJ.TheJournalofNuclearMedicine200849121980~1985.13.J.2003424269~270.2009-11-23、44.1%、36.20%、74.5%、78.7%。22009327.0%200825.2%[2]。80%[3]。68.2%18.2%13.7%。72.3%。80.7%18.5%。、、。221777.3%。、、[4]。。40.7%。3.1、。、。。。、。3.2。、。。。。1S.20072~3.22008R.[2008]130.3.J.200771229~12301239.4“”J.20071163.2009-12-31 !#$%&’()*+,-./0012$%0003!400056007890:;=%0?@A000@BC00!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!709712