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CMYK2003351ChinJOrthopTrauma,March2003.Vol.5.N0.167(1955-)E-mailchenpy99@fimmu.comtwo-wayANOVASPSS10.012112T12-L25SHENGSHENG7CDCD12Asp6136121824Asp21427Asp3311SPSS10.0εN32A1671-7600(2003)01-0067-04AnalysisofvarianceofrepeatedmeasuredataCHENPing-yanDepartmentofHealthStatistics,TheFirstMilitaryMedicalUniversity,Guangzhou510515,ChinaAbstractSometimesresultsareexpressedbyrepeatedmeasuredatainthefieldofmedicalresearch.Inappropriatestatisticalmethodswerewidelyusedinthenationalmedicalliterature.Forinstance,two-wayANOVAorsingleeffectanalysiswereusuallyusedtoanalyzethiskindofdata.ThispaperintroducestherepeatedmeasureANOVA.Forrepeatedmeasuredata,howtoapplytheSPSS10.0toconductdataanalysisandhowtoreportthestatisticallyanalyzedresultscorrectlyinthemedicalliteraturearealsoansweredhere.KeywordsANOVARepeatedmeasuresCrossovereffectMaineffectEpsiloncorrectionZhonghuaChuangshangGukeZazhi(ChinJOrthopTrauma),2003,5(1):67-70CMYK68ºTab.1Maximumdegree(º)ofanteflexionofthespinefixedbyoneoftwoinstrumentsunderfourstatus123456789101112SHENGSHENGSHENGSHENGSHENGCDCDCDCDCDCDCD5.816.327.087.728.206.008.225.059.445.616.588.4013.5313.3916.0317.8011.3510.8622.0415.9017.2110.3215.6419.792.541.7210.414.822.352.734.031.882.540.893.053.275.751.501.955.006.322.921.983.761.241.312.725.15Preischemia1hPost-1h3hPost-3h6hPost-6h12hPost-12h18hPost-18h24hPost-24hSubjectsAreasBeforeorafterischemiaPreischemia2Asp(ng/l)Tab.2ExcitatoryaminoacidAspbeforeorafterischemiaofthecatsatdifferentareas(ng/l)123456123456CentralCentralCentralCentralCentralCentralMirrorMirrorMirrorMirrorMirrorMirror9.6410.089.879.969.769.649.729.999.989.999.899.87146.25144.05145.32145.05140.31140.5820.4622.5422.0522.4322.5820.65187.31185.64186.35185.64186.37186.0933.3734.0533.1433.4134.6133.04208.05213.25213.02213.55211.66210.1139.8338.4538.5639.1838.4536.66294.32298.09298.66296.04293.45298.6115.3716.8717.8115.9717.0118.07314.57315.46314.54314.07314.04314.3311.5911.5511.0410.9911.4211.21263.85264.38261.03266.09265.53262.848.459.049.119.059.239.03SPSS10.02SPSS10.0SPSS1case1variable1292126122112area212123～9time1～time771.SPSSAnalyzeGeneralLinearModelsRepeatedMeasures...RepeatedMeasuresDefineFactor(s)()▲Within-SubjectFactorNametimetime1time2time7▲NumberofLevels77AddDefineRepeatedMeasures▲Within-SubjectsVariable(time)time1～time77▲Between-SubjectsFactor(s)areaOption▲DisplayMeansfortime#ComparemaineffectsConfidenceintervaladjustmentLSD(none)$LSD#DescriptivestatisticsPlot...▲HorizontalAxistime▲SeparateLinesareaAdd2.12CMYK2003351ChinJOrthopTrauma,March2003.Vol.5.N0.169’stestofsphericityMauchly’sTestofSphericity6Fig.6Multiplecomparisonamongthelevelsoftimefactor2MauchlyP0.05P%0.05ε3εGreen-house-Geisser,Huynh-FeldtLower-boundεP=0.000SPSSSigPGreenhouse-Geisser343F=50.502P=0.000F=34.266P=0.00054F=91.521P=0.0006LSD25Fig.5ProfileplotoftimeandgroupingfactorsCMYK70=0.5901.2tt'72Asp2.735Asp35(F=50.502P0.001)F41.77072.823P0.001Asp12h18hAsp6h24hAsp(F=91.521P0.001)Asp(t=0.183,P=0.856)AspP0.001(F=34.266,P0.001)53Asp18h24h73121.SPSS10.0.1.2002.2SPSSInc.SPSSAdvancedStatistic7.5.ChicagoSPSSInc.1997.3....1.2002.200-211.4.SPSS...1.2002.434-455.(2003-02-20)()&FP#FP&FstatisticandPvalueofmaineffect;#FstatisticandPvalueofcrossovereffect.30.715.531.516.131.115.60.1830.856180.965.444.315.7112.683.59.9540.000230.948.956.417.1143.795.316.4950.000233.676.870.733.8152.2101.19.5070.000260.5112.953.029.7156.8132.98.7090.000268.0129.540.222.7154.1147.38.4920.000186.4141.826.614.3106.5128.35.4950.000198.7119.543.126.2122.4&115.3&91.521&0.000&CentralMirrorSumsxsxsxtPAreasofischemiaPreischemia1hPost-1h3hPost-3h6hPost-6h12hPost-12h18hPost-18h24hPost-24hBeforeorafterischemiaSumFP0.00041.77072.8230.0000.000&50.502&(F=34.266,P=0.000)#3Aspng/l,n=6Tab.3ImpactsofdifferentareasonexcitatoryaminoacidAspbeforeorafterischemiaofthecats(ng/l,n=6)