生化过程工程的特点和前沿

13Vol.1No.320017TheChineseJournalofProcessEngineeringJuly20011,2(1.,100080;2.,100080):.().,,.::Q81;R97:A1009−606X(2001)03−0230−091()DNA..().21.[1]()C,N,S,P,H2O.CO2H2O....2001−04−292001−05−20(1940−)..C,N,P,S,C1,F−−.C,N,S,P,.3231.21.20(IT)..VCD..2•2003••(SNPs)••()()()••••••••..−−....3()•2321.•.•.•.()...4.III()GMP3233.5,,.•;•DNA;•;•..,[2]...,,,...,..2341.60%~70%...,,.[3].....6.[3].6.1,..19781982.1986...1988(NRC),..−−()...3235()()...•••••.,..().1988.6.2.....6.3−()−.23616.4...,..6.5,..,()........6.6.,..DNADNA().,GMPGMP.11300323726001143...6.7......90....()..1990..19881014FDA..,..,.....23817.()20.:[1].[J].2000(5):5−11.[2].[A].[C].,1998.15−23.[3].[J].1993,(9):76−95.[4].[M].1998.120−133.FeatureandFrontierofBiochemicalProcessEngineeringOUYANGFan1,2(1.StateKeyLab.Biochem.Eng.,Inst.Chem.Metall.,CAS,Beijing100080,China;2.NationalEngineeringResearchCenterforBiotechnology,Beijing100080,China)Abstract:Bothbiotechnologyindustryandmedicineindustryareprocessindustries.Theresearchoftheirengineeringandtechniquesbelongstothecategoryofprocessengineering.Thisarticlediscussessomecharacteristicsandforwardresearchtopicsofbiochemiscalengineeringprocess,takingbiomedicine,especiallymedicineofgeneengineering,asexamples.Newmedicinedevelopingprocessofgeneengineeringwasthoroughlyanalyzed,andalsotheproducingprocessofmedicine.Thekeyandforwardproblemsintheresearchoftheprocesswereputforwardforreference.Keywords:biotechnology;processengineering;medicine;geneticengineering