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TheNonlinearAnalysisofHeartRateVariabilityiii5(ApproximateEntropy,ApEn)ApEnApEnApEnApEnApEniiAbstractChinesemedicineinducesseveralkindsofChinesemedicalconstitution.Thephysicalreactivityisoftenthechangeofbowels,endocrineandphysicalaction.Thesechangesseemascloseastheregulationoftheautonomicnervoussystem(ANS).InordertodiscusstherelationbetweentheANSandtheChinesemedicalconstitution,theanalysisofheartratevariabilitywasappliedtoassesstheyin-yangconstitutioninChinesemedicine.Sixgroupsofsubjectsincludingnormal,yin-yangexhaustion,yinexhaustion,yinrepletion,yangexhaustionandyangrepletionwererecruitedfromtheinternaldepartmentofChinesemedicineatChinaMedicalCollegeHospital.ECGsignalswereacquiredfromallsubjectsforperiodofapproximatelyfiveminutesinthesupineposition.Inthisstudy,thenonlinearApproximateEntropy(ApEn)analysismethodthatcanquantifythecomplexityofECGsignalefficientlywasadopted.WeexpecttoexhibitconnectionbetweenautonomicnervousactivityandthecomplexityofECG.Theresultscanofferefficientparametersforclinicaldiagnosis.ResultsshowedinnonlinearanalysisthattheApproximateEntropywassignificantlydifferentfromyin-exhaustiongroups,yin-repletiongroupsandyang-exhaustiongroupstothenormals.TheApEnvaluesintheyin-exhaustiongroupswereclosetothoseintheyang-repletiongroups,andthevalueintheyin-repletiongroupswereclosetothoseintheyang-exhaustiongroups.Thereexistssignificantlydifferentfromtheyin-exhaustionandyang-repletiongroupstotheyin-repletionandyang-exhaustiongroups.AccordingtotheChinesemedicine,theyangandyinshouldbebalancetohealthypersons,andtheyang-repletionwillcausetheyinexhaustion.Fromtheresultabove,theApEnvaluecanbeusedtodistinguishtheyin-yangconstitutionKeywordsAutonomicnervoussystemheartratevariabilityyin-yangconstitutionApproximateEntropy(ApEn)iii................................................................................................................................i.......................................................................................................................iiAbstract.......................................................................................................................iii..............................................................................................................................iv..........................................................................................................................vi.........................................................................................................................vii.................................................................................................................11-1.............................................................................................................11-2.....................................................................................................2.........................................................................................................32-1.....................................................................................................32-2.............................................................................................42-2.1..................................................................................42-3.....................................................................................62-4.............................................................................................72-5...................................................................................................10.......................................................................................................153-1...........................................................................................153-2.......................................................................................................173-2.1m........................................................................................203-2.2r..........................................................................................213-2.3N.........................................................................................213-2.4(ApEn)........................................................21iv...................................................................................................234-1...................................................................................................234-2...................................................................................................264-3...................................................................................................30.....................................................................................................................31v2.1................................................................................................................32.2[12].................................................................................................52.3[13].....................................