桑树根皮的药性成分分析以及提取方法

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学号:班级:HUBEIUNIVERSITYFORNATIONALITIES学士学位论文论文题目:桑树根皮的药性成分分析以及提取方法院系:专业:姓名:学号:指导教师:日期:年月日Std.ID:Secret:某某NATIONALTIESSynthesisofBenzotrizoleandItsAlkylDerivativesSchool(department):Subject:Name:Directedby:XXXXX(Teacher)Date:郑重声明本人郑重声明:所呈交的论文是本人在老师的指导下独立进行研究所取得的研究成果。除了文中特别加以标注引用的内容外,本论文不包含任何其他个人或集体已经发表或撰写的成果作品。对本文的研究做出重要贡献的个人和集体,均已在文中以明确方式标明。本论文的所有研究成果所有权归指导老师,他可以将本论文的全部或部分内容编入有关数据库进行检索,可以采用影印、缩印或扫描等复制手段保存和汇编本论文。未经指导老师同意,本人或他人都无权使用文中的成果本人完全意识到本声明的法律后果由本人承担。特此声明学生签名年月日III桑白皮的药性成分分析以及提取方法摘要桑白皮为桑科植物桑MorusalbaL的干燥根皮,系中国药典2005年版收载的常用中药,其性味甘寒,入肺经、脾经,有泻肺平喘,利水消肿之功效,主要用于肺热咳喘,水肿胀满尿少,面目肌肤浮肿。古时候是作为经济林木被广泛种植,用来养蚕抽丝制衣等。随着社会大发展人们有发现它的根皮可以治疗一些病症,因此就更加重视桑树的种植。到现在为止世界各地都或多或少的种植了桑树,主要种植大国有印度、日本、巴西、意大利以及保加利亚等。由此可见它从热带、亚热带、温带到冷温带都广泛分布。本课题主要讨论桑白皮的有效药性成分及其有效成分的提取方法和工艺以及黄酮的测定。关键词:桑根皮脱氧野尻霉素水提取醇提取黄酮IVMorusalbaLvelamenofMedicinalCompositionAnalysisandExtractionMethodABSTRACTMorusalbaLvelamenisRootdryskinforMoraceaeMorusalbaL,DepartmentofChinesepharmacopoeia2005editioncontainscommonlyusedtraditionalChinesemedicine(TCM),Theirsexualflavourgancold,intothelung、spleen、havepurginglung、theeffectofwaterswelling。Mainlyusedforwaterhotcoughasthma、lungswellingfilledwithurine、lessfacialskindropsy、Inancienttimesaseconomictreeshavebeenextensivelycultivated,Tosericulturereeloffrawsilkfromcocoonsclothingetc。Alongwiththesocialdevelopment,peoplehavefoundtherootbarkcantreatsomediseases。sotheypaymoreattentiontothemulberryplanting。Sofarallovertheworldaremoreorlessplantedmulberry,themainplantinglargestate-ownedIndia、Japan、Brazil、ItalyandBulgaria。Thusitfromtropical、subtropical、temperatetocoldtemperatezonearewidelydistributed。ThistopicmainlydiscussSangShuGenskineffectivemedicinalcompositionanditsmethodandprocessofextractingeffectivecomponents。Keywords:MorusalbaL1-DeoxynojirimycinWaterExtractAlcoholExtractFlavonoidsV目录一、绪论.......................................................................................................................11前言.......................................................................................................................12文献综述...............................................................................................................13桑白皮提取物中药化学成分...............................................................................14桑提取物中的活性成分..........................................................................................24.1生物碱...........................................................................................................24.2黄酮和多糖...................................................................................................24.3其他...............................................................................................................25桑白皮提取物的作用...............................................................错误!未定义书签。5.1桑根提取物的酪氨酸酶抑制活性.....................................................35.2降低血糖的作用...................................................................................35.3利尿作用.................................................................................................35.4对艾滋病病毒[HIV]的抵抗作用...........................................................35.5镇咳平喘作用.........................................................................................45.6抗炎作用.................................................................................................5二、实验部分.............................................................................................................51提取........................................................................................................................51.1水提取法.......................................................................................................51.2醇提取法.......................................................................................................52.实验........................................................................................................................6VI2.1实验药品......................................................................................................62.2实验仪器......................................................................................................63实验过程................................................................................................................63.1实验处理......................................................................................................63.1.1药材处理...........................................................................................63.1.2水溶液提取法...................................................................................63.1.3醇溶液提取法...................................................................................63.2部分药品的制备...........................................................................................74测定过程................................................................................................................74.1紫外-可见分光光度法..................................................................................84.2显色法实验过程...................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