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:10021566(2005)04011107:():4,,,,,,,(inreach),,:(),,,,,,,,,4.1,,,,SCI(ISI),ISIJenniferMinnick20001011,1991200125184.1,JASA(JournaloftheAmericanStatisticalAssociation),,HallTitterington(1987),,,:IEEE111::()©1995-2005TsinghuaTongfangOpticalDiscCo.,Ltd.Allrightsreserved.4.1,J.Microscopy,BiomedicalEngineering,JournaldePhysique,,500,1524.2,,,,,,,19721975,(partiallikelihoodanalyses),4.2,,,,,4.2:NSF,,Science,,,(FDR)1/4,8:,(TheAstronomicalJournal),Science,,,4.3,,21125420057©1995-2005TsinghuaTongfangOpticalDiscCo.,Ltd.Allrightsreserved.4.3,P-(80()(Simes)),,FDR,,CMU()FDR,,MillerNichol,,,,ScienceMillerNichol,,FDRCMUBobNichol:,CMU,FDR,,(),,,,4.3,,,,,,,,()4.3.1:,,1994Huber,311::()©1995-2005TsinghuaTongfangOpticalDiscCo.,Ltd.Allrightsreserved.102,104,106,108,1010(Wegman,1995),,BaBaR51015,100,,,,(General2izability)(scalability),,,4.3.2:(R.A.Fisher),:(ancillarity),,,,,4.3.3,,,,,4.3.4pn,(p)(n)DNA(Leiden):pmn,,,40,((n)(p)),,npnp,Tracy-Widom,,4.3.541125420057©1995-2005TsinghuaTongfangOpticalDiscCo.,Ltd.Allrightsreserved.,,(MLE),,4.3.6()(),,,,,,,,4.4,?,,,,(),,4.4.1,:,,,,4.4.2,,,,,:FDR/:,StephenStigler,AnnalsofStatistics,,25%,,2070%35%511::()©1995-2005TsinghuaTongfangOpticalDiscCo.,Ltd.Allrightsreserved.,4.4.3:(),,()()(MCMC),():4.4.4,,(inreach),:,,4.4.5,?,,,(),A(B,C)(),ABCDA(B,C)()A(),,,A,?,/B,B,,B,61125420057©1995-2005TsinghuaTongfangOpticalDiscCo.,Ltd.Allrightsreserved.,,,()(55)[][1],.DEA[J].,2002,11:92-95.[2],.[J].,2003,6(2):47-53.[3],.[J].,2002,22(6):126-130.[4]FriedmanJH,TurkeyJW.Aprojectionpursuitalgorithmforexploratorydataanalysis[J].IEEETransoncomputer,1974,23(9):881-890.[5],,.[J].,2002,22(6):131-134.[6],,,.[J].,2002,19(6):53-55,61.(69)[][1],,.[J].003,21(1):33-37.[2],.[M].:,2000.[3].[M].:,2002.[4],.[N].,2003-08-14.[5].:[M].:,2002.[6]GrinblattM.,TitmanS.,Persistenceofmutualfundperformance[J].Journaloffinance,1992,47(5):1977-1984.711::()©1995-2005TsinghuaTongfangOpticalDiscCo.,Ltd.Allrightsreserved.