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主要缩略语中英文索引缩写词英文全称中文全称ABCA1ATP-bindingcassettetransporterA1三磷酸腺苷结合盒转运体A1ABCATP-bindingcassette三磷酸腺苷结合盒ABCG1ATP-bindingcassettetransporterG1三磷酸腺苷结合盒转运体G1ActDActinomycinD放线菌素DAdadenovirus腺病毒ApoA-IApolipoproteinA-I载脂蛋白A-IApoE-KOApolipoproteinEgeneknockout载脂蛋白E基因敲除apoA1apolipoproteinA1载脂蛋白A1ApoBapolipoproteinB载脂蛋白BApoEapolipoproteinE载脂蛋白EapoE-/-miceApolipoproteinE-deficientmice载脂蛋白E基因缺陷小鼠AsAtherosclerosis动脉粥样硬化BAbetulinicacid白桦脂酸Bcl-2B-celllymphoma-2B淋巴细胞瘤-2BSAbovineserumalbumin小牛血清蛋白CADCoronaryarterydisease冠状动脉性疾病cAMPCyclicadenosinemonophosphate环腺苷酸CAV-1caveolin-1小凹蛋白-1cDNAComplementaryDNA反向转录DNACETPcholesterylestertransferprotein胆固醇酯转移蛋白CECholesterolester胆固醇酯CRPC-reactiveproteinc反应蛋白CMChylomicrons乳糜微粒CREcAMPresponseelementCAMP应答元件CREBCREbindingprotein反应结合蛋白CXCL1Chemokine(C-X-Cmotif)ligand1cxc趋化因子配体1Diodiosgenin薯裁皂苷元DTTDithiothreitol二硫苏糖醇DMEMDoubecco'smodifiedeaglemedium改良的Eagle培养基dNTPDeoxy-ribonucleosidetriphosphate脱氧核糖核苷三磷酸盐EDTAEthylenediaminetetraaceticacid乙二胺四乙酸ELISAenzymelinkedimmunosorbentassay酶联免疫吸附测定ERKextracellularsignal-regulatedkinas每分钟计数FCFreecholesterol游离胆固醇GIPglucose-dependentinsulinotropicpolypeptide糖依赖性胰岛素释放肽HDLhighdensitylipoprotein高密度脂蛋白HDL-CHighdensitylipoproteincholesterol高密度脂蛋白胆固醇HEPESN-2-Hydroxyethylpiperazine-N'-2-ethanesul-fonicacid羟乙基哌秦乙硫磺酸HPLCHighPerformanceLiquidChromatography高效液相色谱HSPGheparansulphateproteoglycans硫酸乙酰肝素糖蛋白HMGCRHMG-CoAreductase3一轻-3一甲基戊二酞辅酶A还原酶HLhepaticlipase肝酯酶IκBInhibitorofkappaB核因子κB抑制蛋白IFN-γInterferon-gamma干扰素γIL-1βInterleukin-1β白细胞介素1βIL-6Interleukin-6白细胞介素6IL-8Interleukin-8白细胞介素8ICAM-1intercellularadhesionmolecule-1细胞间粘附分子-1IKK-βinhibitorofkappaBkinas-β核转录因子κB抑制蛋白激酶JNKJunN-terminalkingsJun氨基末端激酶LDLLowdensitylipoprotein低密度脂蛋白LDL-CLowdensitylipoproteincholesterol低密度脂蛋白胆固醇LDLRlowdensitylipoproteinreceptor低密度脂蛋白受体LPSLipopolysaccharide脂多糖LPLlipoproteinlipase脂蛋白脂酶LXRliverXreceptor肝X受体MCP-1monocyteschemotacticprotein-1单核细胞趋化蛋白一1mRNAmessengerRNA信使核糖核酸MTPmicrosomaltriglyceridetransferprotein微粒体甘油三酯转运蛋白MIP-1αmacrophageinflammatoryprotein-1α巨噬细胞炎性蛋白1αmTORmammaliantargetofrapamycin哺乳动物雷帕霉素靶蛋白miRNAsmicroRNAs小分子RNAMMP-1Matrixmetalloproteinase1基质金属蛋白酶1nCEHeutralcholesterolesterhydrolase中性胆固醇脂水解酶NPC1Niemann-PickC1protein尼曼一匹克蛋白1NPC1L1,Niemann-PickC1like1protein尼曼匹克C1型类似蛋白1NF-kBNuclearfactor-kappaB核转录因-KBNODnucleotide-bindingoligomerisationdomainproteins核苷酸结合寡聚结构域蛋白NLRP1NOD-likereceptorprotein1NOD样受体蛋白1NLRP3NOD-likereceptorprotein3NOD样受体蛋白3ox-LDLOxidizedlow-densitylipoprotein氧化低密度脂蛋白PBSPhosphate-bufferedsaline磷酸盐缓冲生理盐水PDTCpyrrolidinedithiocarbamate二硫代氨基甲酸吡咯烷PMAPhorbol12-myristate13-acetate佛波酯PI3KPhosphatidylinositol3-kings磷脂酰肌醇3-激酶PKB/AKTproteinkingsB蛋白激酶BPVDFPolyvinylidenefluoride聚偏二氟乙烯RCTReversecholesteroltransport胆固醇逆向转运Real-timePCRReal-timequantitativePCR实时定量PCRRXRRetinoidXreceptor视黄醇X受体RT-PCRreversetranscriptionpolymerasechainreaction逆转录聚合酶链反应SDSsodiumdodecylsulfate十二烷基硫酸钠SDS-PAGESodiumdodecylsulphate-polyacryiamide聚丙烯酞胺凝胶电泳siRNAsmallinterferingRNA小干扰RNA分子SR-AScavengerreceptorA清道夫受体ASR-B1scavengerreceptorclassBtype1B型清道夫受体1SREBPsterolregulatoryelement-bindingbindingprotein固醇调节原件结合蛋白SREBPsSterolregulatoryelementbindingproteins固醇调节元件结合蛋白TBAThiobarbituricacid硫代巴比妥酸TCtotalcholesterol总胆固醇TDTangierdisease丹吉尔病TGtriglyeride甘油三酯TNF-αTumornecrosisfactor(TNF)-α肿瘤坏死因子αTGF-βtransforminggrowthfactor-β转化生长因子-βVCAM-1vascularcelladhesionmolecule1血管内皮细胞粘附分子-1VLDLverylowdensitylipoprotein极低密度脂蛋白XIAPXchromosomelinkedinhibitorofapoptosisproteinX连锁凋亡抑制蛋白3`-UTR3`-untranslatedregions3`-非翻译区