XXXX年仪器设备-生物大分子相互作用仪目录

file:///G|/OPW/pp/download/bihec_pdf_bycat/2010-.htm[2010-4-2619:09:23]JPKNanoTracker™Zeiss,Nikon,Olympus,Leica1.Nanotracker™Nanotracker™CLSMFRAPNanotracker™DICNanotracker™2.Nanotracker™35mm60CO23.Nanotracker™Nanotracker™4.•DNA,motorproteins,…•Molecularmechanics•Lateralorganization(e.g.,lipidrafts)•Trans-membraneprocesses,trafficking•Singlebindingevents•Cyto-toxicity,nano-toxicity•Endocytosis•Biologicalbarriers•Localdrugdelivery•Entrancemechanism•Pathogen-hostinteraction1.Nanotracker™100×100×100μm320×20mm22.Nanotracker™JPKNanoTracker™file:///G|/OPW/pp/download/bihec_pdf_bycat/2010-.htm[2010-4-2619:09:23]1064nm0.05%3W13.Nanotracker™60MHz16bitXYZ16TTL4.Nanotracker™“PointandTrap”DirectOverlay™JPK©2005-2009()9892006,200031,021-60896520,[e-mail]esSPP(SPPSPS)PULSETube335,000PSI135000PSI(SPP(PULSETube)DNARNAPULSETubes:BiotechnologyAntibioterrorismDrugDiscoveryAgricultureAquacultureEnvironmentalSciencePaleobiologyGenomicsTranscriptomicsProteomics1)/2)(PULSETube)PULSETube3)4)5)35,000psi6)7)SPPSPPIIIfile:///G|/OPW/pp/download/bihec_pdf_bycat/2010-.htm[2010-4-2619:09:23]8)PCR/9DNARNA,SPP1)2)3)PULSETube4)220VAC,60Hz5)15~35°C85%6)1~37)45kpsi,310MPa8)5~35kpsi2380Bar9)35kpsi310)0.311)9912)99s13)2514)CE©2005-2009()9892006,200031,021-60896520,[e-mail];;2(~10nl/);:3*10-6ofRI.3pg/mm2.:40-801ul:20ul:1.00-1.45:8-40©2005-2009()9892006,200031,021-60896520,[e-mail]-Navifile:///G|/OPW/pp/download/bihec_pdf_bycat/2010-.htm[2010-4-2619:09:23]ESPRSurfacePlasmonResonanceSPRØØØØØØØØ0.520~100ml100Ag/AgClSPRSurfacePlasmonResonanceØØØØ:670nmØØØØ0.8~227ul/sØ20~150ulØSPR68~78Ø4000(0.5)Ø122=1ng/mm210^-3~0.4X10^-11Ø0.05(=0.4RU)©2005-2009()9892006,200031,021-60896520,13661956095ESPRESPRITfile:///G|/OPW/pp/download/bihec_pdf_bycat/2010-.htm[2010-4-2619:09:23]@bihec.comBiosuplar400Biosuplar400TIvium“-ESPR”*SPR*20μl*2**670nm*17˚*3m˚*SPR*Biosuplar400T©2005-2009()9892006,200031,021-60896520,[e-mail]®BiosuplarSPRBiosuplar400400TJPKForceRobot200500file:///G|/OPW/pp/download/bihec_pdf_bycat/2010-.htm[2010-4-2619:09:23]UnattendedModeloadingrate2480,000XYZ0.1nmRMS0.1-1kHz0.2nmRMS0.1-10kHzz4μm×4μm×4μm2mm×2mmOlympus®BioleverFPGA/DSPGb4-800.1Microsoft®Windows®JavaTM1,200,000ForceclampRamp‘planner’≈76cm×131cm×101cm≈270kgUnattendedModeloadingrate2480,000XYZ0.1nmRMS0.1-1kHz0.2nmRMS0.1-10kHzfile:///G|/OPW/pp/download/bihec_pdf_bycat/2010-.htm[2010-4-2619:09:23]z4μm×4μm×4μm2mm×2mm©2005-2009()9892006,200031,021-60896520,[e-mail]ctionAnalysisBiacoreBiacoreBiacoreBiacoreBiacore!BiacoreT1002005(SPR)Biacore3SPRBiacore-(Proteomics)-(CancerResearch)-(DrugDiscovery)-(CellSignalling)-(Multi-molecularComplexes)-(MolecularRecognition)-(ImmuneRegulation)-(Immunoassay)-(VaccineDevelopment)-(TransientBinding)-(LigandFishing)-(BindingSpecificity)-(Structure-functionRelationship)-(EnzymeReaction)**BIACORE**BIACORE**4000NatureSciences40**1.-DNA-DNA-DNABiacoreT100file:///G|/OPW/pp/download/bihec_pdf_bycat/2010-.htm[2010-4-2619:09:23]2.3.4.100Da5.1.2.2x96+83.5-750ul4.1.33-1.405.6.7.8.9.1-5/10.0.02ul11.412.13.100Da14.GxP©2005-2009()9892006,200031,021-60896520,[e-mail]onanceSPR0.520~150ul100Ag/AgClSPRØSurfacePlasmonResonanceØØØØESPRfile:///G|/OPW/pp/download/bihec_pdf_bycat/2010-.htm[2010-4-2619:09:23]ØØ0.5~100ul/sØ20~150ulØSPR68~78Ø4000(0.5)Ø122=1ng/mm210^-3~0.4X10^-11Ø0.05(=0.5RU)©2005-2009()9892006,200031,021-60896520,[e-mail]--DPI(DualPolarizationInterferometry)DPIAnaLight12Alzheimer's3456--1234DPI”“DPIDPI0.1A0.1pg/100000Da50Da5DaDPINMRXX-rayCrystallographSPRQCMAnaLightBio200DPIAnaLightXAnaLightBio200©2005-2009()9892006,200031,021-60896520,[e-mail]4D,Bio200file:///G|/OPW/pp/download/bihec_pdf_bycat/2010-.htm[2010-4-2619:09:23](SPR)(SPR,SurfacePlasmonResonance)(SPR)10SPRSPR()1.SPR2.3.4.vs.5.0.35µRIUrms(0.25RU)6.0.1μRIU/min7.1.32-1.68.10°C-90°C()(ΔH)9.10.11.12.HPLC(0.0025to0.04)13.3700CCD14.LED15.()16.17.18.vs.,19.*()DNARNA*//*(on-forward-association,off-reverse-dissociation)***©2005-2009()9892006,200031,021-60896520,[e-mail](SPR)SR7000DCBiosuplar6file:///G|/OPW/pp/download/bihec_pdf_bycat/2010-.htm[2010-4-2619:09:23]SPRSPR1.2.3.4.5.176.(SERS)AFMSEMFT-IRspectroscopy7.SPR:(1),;(2),;(3),1μg;(4),;(5);(6);(7);(8);(9),;(10)SPR,,SPR20ul630-670nm20s2S0.1s170.003USB2.5Kg20×9×8Windows2000/98WindowsXPCPUfile:///G|/OPW/pp/download/bihec_pdf_bycat/2010-.htm[2010-4-2619:09:23]500MHz©2005-2009()9892006,200031,021-60896520,[e-mail]1.2.1—15min/3.pg4.5.OWLSOWLS120MicroVacuum-*DNA-OWLS120file:///G|/OPW/pp/download/bihec_pdf_bycat/2010-.htm[2010-4-2619:09:23]0.080m3(535×500×300mm)*He-Ne