•OverviewofresearchinBiophysicsInstitute@NCU.中央大學生物物理所•FromDNAtocollectivebehavioroforganisms中央大學生物物理所PhysicsDept.CenterforComplexSystems複雜系統中心BrainResearchCenter,UST聯合大學腦科學中心LifeScience生命科學系InstituteofPhys.,AcademiaSinica中研院物理所Inst.SystemsBiology&Bioinformatics系統生物所WhyBioPhysics?•MaterialNatureofBio-substancesaffectBiologicalproperties.(Evolutionmadeuseofthephysicalpropertiesofbio-materials)•Physicalprinciples&Lawsholdsfrommicroscopiclevelmacroscopiclevel•TraditionalBiologyisdescriptive,non-quantitativeWhyBioPhysics?•Physicsisuniversal.•Riseofmolecularbiology:DNA,RNA,proteinareuniversalinalllivingmatters•UniversalityinCentralDogma:DNARNAproteinBiologicalfunctions…•New,interesting,exciting&useful.•Lotsofunsolvedimportantproblems.•Techniques&Methodologyinphysicscanprobethefundamentalprinciplesinbio-systemsofawidespectrumofscalesinaquantitativeway.國立中央大學生物物理研究所•Officiallyestablishedin2004•教授:6副教授:1助理教授3•合聘教授:2合聘助理教授:1•現有從事生物物理領域在學研究生碩士班:23博士班:8•博士後:3•以物理之技術或方法去探討生物系統中存在之基本原理,從而對生物過程提供深入及定量之了解。•「5年500億」頂尖中心經費建立生物物理共用核心設施•歡迎物理與非物理背景同學加入.中大及中研院提供獎學金BioPhysicsInstitute@NCU•Officiallyestablishedin2004•Professors:6Assoc.Prof.:1Assist.Prof.3•Adj.Prof.:2Adj.assist.prof.:1•GraduatestudentsworkingonareasinbiophysicsM.S.:23Ph.D.:8•Postdocs:5•aimsatachievingsomequantitativedescriptionofbiologicalprocessesandsearchforthefundamentalprinciplesburiedinthesehighlycomplexbiologicalphenomena•「5years500B」granttosupportresearch&buildingofcorefacilitylabs.•Cross-disciplinary:researchers/studentsfromphysics&non-physicsbackground師資職稱Ph.D研究專長EmailAddress李弘謙Hoong-ChienLee教授ProfessorMcGillUniversity計算生物/生物物理/生物訊息(理論)hclee@sansan.phy.ncu.edu.tw伊林LinI教授ProfessorRutgersUniversity複雜系統/生物物理(實驗)lini@phy.ncu.edu.tw陳方玉Fang-YuChen教授ProfessorRiceUniversity生物物理/生物膜(實驗)fychen@phy.ncu.edu.tw黎璧賢Pik-YinLai教授ProfessorUniversityofPittsburgh生物物理/軟凝態物理/神經元網路/生物材料(理論/實驗)pylai@phy.ncu.edu.tw王敏生Min-ShengWang教授ProfessorUniversityofPittsburgh腦科學(理論)mswang@phy.ncu.edu.tw高仲明Chung-MingKo教授ProfessorUniversityofArizona演化的模擬(理論)cmko@phy.ncu.edu.tw陳培亮PeilongChen副教授AssociateProfessorCaltech生物圖案形成/軟物質/生物力學(理論/實驗)peilong@phy.ncu.edu.tw陳宣毅Hsuan-YiChen助理教授AssistantProfessorUniversityofPittsburgh軟凝態物理/生物物理(理論)hschen@phy.ncu.edu.tw薛雅薇Ya-WeiHsueh助理教授AssistantProfessorUniversityofToronto生物膜物理/核磁共振(實驗)yhsueh@phy.ncu.edu.tw李紀倫Chi-lunLee助理教授AssistantProfessorSUNYStonyBrook軟凝態物理/生物物理(理論)chilun@kali.pse.umass.edu陳志強Chi-KeungChan合聘教授JointAppointmentProfessorUniversityofPittsburgh軟物質/生物物理/神經元網路(實驗)phckchan@ccvax.sinica.edu.tw梁鈞泰Kwan-taiLeung合聘教授JointAppointmentProfessorUCSantaBarbara統計物理與軟物質/生物集體行為(理論)leungkt@phys.sinica.edu.tw林耿慧Keng-HuiLin合聘助理教授JointAppointmentAssistantProfessorUniversityofPennsylvania軟物質/生物材料(實驗)khlin@phys.sinica.edu.twWideSpectrum•LengthScales:nmmmmmcmmkmDNA,RNA,protein,intracellular,virus,bacteria,Intercellular,collectivemotion,insects,animanls/plants,migration•TimeScales:fspsmsmssetransfer,H-bonding,waterDNA,RNA,proteinrearrangement,proteinfoldingDNAtranscriptionhrdayyearByrcelldivisionEarthorganisms,animalmigrationevolution•Knowledge:Interdisciplinary跨越各學科領域MathematicsPhysicsChemistryBiologyMedical•BiophysicistisaTRUEScientist!•需要物理與非物理背景人材加入!BioPhysicsTheoryGroupsatNCU•陳培亮PeilongChen:bio-hydrodynamics,mechanicsofpropulsioninlivingorganisms,patternformationinbiology•陳宣毅Hsuen-YiChen:complexfluids,celladhesion,collectivemotioninflocks•黎璧賢Pik-YinLai:DNAphysics,biomolecularchainmodels,neurons,biologicalnetworks•李紀倫Chi-LunLee:proteinfolding,chargedbiomolecules•梁鈞泰Kwan-taiLeung:self-propellingmotioninorganisms,flocking,non-equilibriumbio-processes•高仲明Chung-mingKo:Evolutionmodels,astrobiology•王敏生Min-ShengWang:NeuralNetworks,brainwave&MEGanalysis•李弘謙Hoong-ChienLee:Bioinformatics,proteinphysics,genome/DNAsequenceanalysisSoftmattersBiophysicsBioPhysicsExperimentalLabsatNCU•ComplexSystemLab.伊林LinI:micro-motionofbio-andsoftmaterialsinconfinedspots,dynamicsofneuronalsystem,laserpulse-softmatterinteraction•BiophysicsLab.陳方玉FangYuChen:Biomembrane,Membrane-activePeptides,Effectofpeptide-formingporeonneuronfunction•Soft-condensedMatterLab.陳培亮PeilongChen:bio-hydrodynamics,mechanicsofpropulsioninlivingorganisms•Bio-SoftMattersLab.黎璧賢Pik-YinLai,陳志強C.K.Chan&林耿慧K.H.Lin:interactionsincells,neuronalnetworks,DNAmechanics&hydrodynamics,biomaterials•Bio-SoftCoreFacilitiesLab.:BioAFM,Confocalmicroscopy,WetLabs,Biosamples,fastimagingsystems,fluorescencemicroscopy…•Bio-membraneLab.薛雅薇Ya-WeiHsueh:lipidraftsincellmembranes,NMRspectroscopy,AFMmeasurementE