角蛋白的分子构成-提取及应用

3(730070)2007204210,2007212218,,,,,AdvancedinStructure,ExtractandApplicationsofKeratinsJiaRuyan,HeYufeng,WangRongmin3,LiFangrong,WangYan(KeyLaboratoryofPolymerMaterialsofGansuProvince,InstituteofPolymer,NorthwestNormalUniversity,Lanzhou730070)AbstractThesources,compositionandstructuresofkeratinwereintroduced.Thepattern,macroscopicstructuresandcompositionofhairsandfeatherwerediscussedtoo.Themethodsforextractingkeratinfromhairsandfeatherweresummarized.Thetypicalchemicalmethodsareacid2basehydrolysis,reductionandoxidation.Themolecularweightandyieldofkeratinwereanalyzed.Thekeratinanditsderivativeswereappliedtofeed,hairdressingandmedicine.Itsapplicationsinmaterialsandbiomedicinehavealsobeendeveloping.KeywordsNaturalPolymer,Keratin,Hair,Structure,Application,19,20,,;,,,,,1,;[1],,,,[2][3],,111,562http:PP[4],[5,6],11211211192,,,[7]Parry[8],,:A(C2C2X2P2X)B(C2C2X2SPT2SPT),C(Cys),P(Pro),S(Ser),T(Thr),XAC2C2Q2P2X(A1)C2C2R2P2X(A2)AB,,,AB,A1BA2BAB1920BABA1BA1AA,2[9],1[10]1Fig.1Theschemeofaminoacidrepeatedunitsinkeratinmolecules112122(2)(3),222,2,2[11]22Fig.22spiralstructureofkeratin3Fig.3Thearrangementofhydrogenbondin2foldofkeratin2,,2[12]266220084http:PP(2)22,2,,,2,2112132,,[13],,,4[14],NC2,,22(L12),L1L2[15],,2,,2[16],,,[17]4Fig.4Therelationofdimerinkeratinwithhairfiber2,,,,,,,,,,,211,,,,762http:PP[18],,,,,[7][19],,,212,,,21211,,,,,,,;,;,[15]21212,,22[20],,,,[21];([22]),[23],;,,[24]://,,,,4080kD,,,;21213,PSSP+[O]PO3H[22][2]Na2SO3,S2,S2,S2,,,21214[25],,,,,,,21215,,[32],,,,;21216[32],,86220084http:PP[26],,214,Folin[27],,,[28],,,,[29]3;[30],311,[31]:[32][33]150100Ca(OH)2,,[34],,[35],,,,,,,312,,,;,31211,[36],[37],[38][39],,,,,31212,,,[40],[41][42],,,,;,,,,,31213[43],962http:PP(),[44]31215,,[45],010010102SPcm,114119mmolPg31216[46],,,,,313[47],,,,,,,4,,,,;,(),,,,,,,,,,,[1],,.,1998,40(9):790795.[2]RJ,GH,AD2.CN:1535280A,2004.[3]TCOConnell,REMHedges.J.Archaeol.Sci.,2001,28:12471255.[4],..:,1991:45.[5]JMMaxwell,MG.Huson.Micron,2005,(36):127136.[6]SBreakspear,JRSmith,GLuengo.J.Struct.Biol.,2005,149:235242.[7],.,2002,16(12):6567.[8]DADParry,TA.Smith,MARogersetal.J.Struct.Biol.,2006,155(2):361369.[9]RDBFraser,DADParry.J.Struct.Biol.,2006,4(24):48.[10]JWHearle.Int.J.Biol.Macromol.,2000,27(2):123138.[11]MToni,LAlibardi.Zoology,2007,(110):4147.[12]JNCao.J.Mol.Struct.,2002,607(1):6975107220084http:PP[13]CDanciulescu,BNick,FWortmann.Biomacromolecules,2004,5:21652175.[14]PACoulombe,MBOary.CellBiology,2002,14(1):110122.[15]LHGu,PACoulombe.CellBiology,2007,19(1):1323.[16]KShari,AMKamala,YNomuraetal.,1994,(12):127130.[17]MYoshida.OrganicCoatings,1997,31(122):6372.[18],.CN:1057377A,1992.[19].CN:1056986A,1991.[20],..:,1998:20.[21],,.,2005,(2):2627.[22]PMMSchrooyen,PJDijkstra,RCOberthuretal.J.ColloidInterfaceSci.,2001,240(1):30391[23]G.Ozdemir,OESezgin.ColloidsandSurfacesB:Biointerfaces,2006,52(1):17.[24],,.CN:1680476A,20051[25].,2003.[26],,.,2005,(11):4748.[27]MFolin,EContieroyguo.ForensicScience,1996,83(3):191199.[28],.,1991,11(2):2124.[29]NMirancea,IHausser,DMetzeetal.DermatologicalSci.,2007,45(3):175185.[30],,.(),2003,26(6):364366.[31],.,2003,(5):3637.[32]GCoward2Kelly,VSChang,FKAgbogboetal.Bioresour.Techn.,2006,97(11):13371343.[33]GCoward2Kelly,FKAgbogbo,MTHoltzapple.Bioresour.Techn.,2006,97(11):13441352.[34],.CN:1057377A,1992.[35],,.,2005,22(4):2225,41.[36],.,2005,19(9):111113.[37],.,2004,8(23):48054807.[38],,.,2006,10(1):174176.[39],,.,2006,20(10):3135.[40],,.CN:1680467A,2005.[41],,.2004,(8):4143.[42].CN:1119229A,1996.[43],.CN:1555393A,2004.[44],.,2002,15(3):341346.[45],,.CN:1736609A,2006.[46],,.CN:1671740A,2005.[47],.CN:1660901A,2005.19786Email:jrygfz@1631com1966101998Email:[e-mail]172http:PP