1212345678a-b-91011R1213NH2COOH14N-C-151617181.2.3.4.a-1ABCDE1()ABCDE2()ABCDE3()ABCADPD13E4()AIMPBAMPCGMPDXMPEATP5SCOA()AACPBCDEA6()ABCDE7()ANADHFADH2BGTPCCOADE8()AHMGCOABHMGCOACHMGCOADCOAE9()ABCDE310DNA()2ABCDE11()ABCDE12()ABCDE13()AUAGBUAACUGADAUGEAGU14()ABCDE15()ABCDE16()ABCDE17()ABCDE18DNA()ADNABCDNADDNAEDNA19()ABC63D6E20()ABCDE21()ABCDE22()ABCDE23()AG1PBG6PCUDPGDCDPGEGDPG24()ABCDE25()ABCDGTPEP26()ADNABDNACDNADRNADNAERNADNA27()AKmVmaxBKmVmaxCKmVmaxDKmVmaxEKmVmax28()AVLDLBCMCHDLDIDLELDL29()A4BYCDZE30()AATPBADPCCTPDCDPEUDP31()A23B25C35DE32()ABCDE33()ABCDE34()ABCCO2DE35()ABCDE36()A1B2C3D4E51(PI)______PHPI______PHPI______2________________________3COA____________________________________ATP4RNA__________________5________________________6________________________7MRNA5______3______8__________________9_______________________________10__________________511Ca2______K______12VitD______13__________________14______________________________15WatsanCrick____________bp16__________________17__________________18__________________19________________________________________________20____________21______________________________22__________________23__________________24________________________25______________________________26__________________27__________________28DNA__________________1234567r8DNA910111212?345661E2D3B4A5B6B7D8C9D10B11D12B13D14D15B16E17E18D19D20C21A22C23C24D25E26C27A28A29C30D31C32C33D34C35D36C12CMVLDLLDLHDL3A5422567M7GPOLYA8PAPSSAMPRPP9CH3=CH2CH=CHOCH=NHFH4105r1112125(OH2)VitD313CoAFe2141510161718Ca219TPPFADNADCoASH2021PH22VitD32324HKNaHCO325NADNADPFADFMAQ262728DNA1()234ADPATP75H(2H=2e2H)H2O6ABCDE()7rGSHrr8DNADNA9DNADNADNA()101112RNA4SRNARNA4dNTPDNA()81040gA200gB250gC640gD300gE625g2ABCDE3ABCDE4ABCDbioooE5ABCDE6ApHpIBpHpICpHpIDpH74E7bioooABCDE8ABCDE9pI8pHA8B8C8D8E810ABCDE1ABCD29ABCD3ABCD4-A36BCDR5A-B-C-D6-ABCD7ABCD8pH5ApI45BpI74CpI7DpI659ABCD10ABCD1___________________________________2________________%3_______________pH_________pH__________4__________________5________________________6__________________7_________________10________810_______10__________________________________1B2E3D4B5E6C7D8D9B10E1AD2ACD3ABD4ABD5ABCD6ABC7BCD8BCD9AC10ABC12163456781AC-5BC-2CC-3DC-2C-5EC-2C-32ABCDE3RNADNAABC11DE4A23BC25DE355A280nmB260nmC200nmD340nmE220nm6RNAAmRNABtRNARNACmRNADRNAmRNAtRNArRNAErRNA7mRNA3-AABUCTDCEG8DNAABCDNADEDNA9DNATmAG+ABC+GCA+TDC+TEA+C1210DNA15%A15%B30%C40%D35%E7%1DNAAA+C=G+TBC=GCA=TDC+G=A+T2ANAD+BNADP+CFADDFMN3DNAABCD4DNAABDNACDNADDNA5DNAABA-TG-CCD6tRNAA3AB5C-C-A13CD7DNAABCD8mRNAAB3-CD5C-C-A9TmATmBDNAGCTmCTmDDNAATTm10DNAABDNACD-1___________________________________________________2___________________________________________RNA_________3_________________________________4__________________5ATP__________bCDP________6RNA____________________tRNA14_________7tRNA________________________________________8tRNA____________________----------------------------------------------------------------------------------------------------------------------------------------------------------------151A2D3A4E5B6C7A8D9B10D1ABC2ABC3AC4BD5ABCD6DE7AB8ABC9ABC10AC123914cAMPcGMP567TC81ABCDE2ABCDE3ABCDE4A16BCDE5NADP+BABCDE6ABCDE78=1/2KmvVmaxA025B033C050D067E0758ABCDE9pHABCpHDEpHKm10AB17CDE11KmABVmCKmD1/2VmE1ABVmCDKm2ABVmCDKm3ABCD4FADAB2BCGMPDADP5ABKmCD618ABCD7ABCD8ABCD9ApHBCD10ABCD1________________________________________2vVm80%[S]Km___________vVm90%[S]Km__________3Km________Km________Km__________4__________Vm5__________Km6LDH________________________________LDH119__________7L-L-D-_________8_________________----------------------------------------------------------------------------------------------------------------------------------------------------------------201C2B3C4C5D6C7B8E9D10C1ABCD2BCD3BCD4ABD5AB6BCD7BCD8ACD9ABCD10AB12493456HM5781mg/100mlA60100B60120C70110D80120E1001202A6-B6-C16-D3-E13-3A***AB1BB2CB6DPPE214AADPBGDPCCDPDTDPEUDP5ABCDE6ABCDE7ABC-6-DE8AB3-CDE91ATPA1B2C3D4E51022AAMPBADPCATPD26-E16-11ATPAB-C-DE12AABCDAE13ATPA2B2C2D2E2-14A1-B6-C16-D3-E6-15A-6-BCD6-E231AATPBGTPCUTPDCTP2A6-BNADH+H+CNADPH+H+D5-31A3CO2B15ATPC5NAOHH2OD4AA+B-C-ADA5ABCD6ABCD7ABCD8AFAD24BTPPCNAD+DCoA9ABCD10AATPBGTPCUTPDCTP11ABCD12AB3-CD13ABCD14ABCD15AABC25D1____________________2_________________3_________________4____________________5_____________________6_______________________7__________________ATP81________ATP1____________ATP----------------------------------------------------------------------------------------------------------------------------------------------------------------261C2E3C4E5E6B7C8C9B10D11C12D13C14B15D1AC2CD3ABD4ABC5ABD6AC7AB89AB10AB11BCD12BC13BCD14ACD15ABCD123454267823----1ABCDE2ApoABApoALCATCApoBLDLDApoCEApoCLPL3ACMVLDLIDLLDLBCMVLDLLDLHDLCVLDLCMLDLHDLDVLDLLDLIDLHDLEVLDLLDLHDLCM427ACMVLDLLDLHDLBVLDLLDLHDLCMCLDLHDLVLDLCMDHDLVLDLLDLCMEHDLLDLVLDLCM5ABCDE6ABCDE7ABCDE8ACoABCoACCoADCoAFAD?2HNAD++H+EH2OCO29ABCoACDHMGCoAE10AB28CDE11ABCoANADPH+H+CCoADECoA12AB2-C3-DE13AATPCTPBNADPH+H+CDES-14AHMGCoABHMGCHMGDHMGCoAEHMG15ABCDED31AB29CD2ABCD3A-BCDapoB1004ACMB