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()()1)HisashiUeta,HidekoNagasawa,YurikoOyabu-Manabe,KazunoriToida,KazunoriIshimuraandHitoshiHori:Localizationofenolaseinsynapticplasmamembraneasanagheterodimerinratbrain,NeuroscienceResearch,Vol.48,No.4,pp.379–386,2004.2)HitoshiHori,HidekoNagasawa,YoshihiroUto,KazutoOhkura,KennethL.Kirk,YoshimasaUeharaandMarikoShimamura:DesignofHypoxia-TragetingProteinTyrosineKinaseInhibitorusinganinnovativepharmacophore2-methylene-4-cyclopentene-1,3-dione,BiochimicaetBiophysicaActa(BBA)-Proteins&Proteomics,Vol.1697,No.1-2,pp.29–38,2004.3)AyukoTakao,HideakiNagamuneandNobukoMaeda:IdentificationoftheanginosusgroupwithinthegenusStreptococcususingpolymerasechainreaction,FEMSMicrobiologyLetters,Vol.233,No.1,pp.83–89,2004.4),,,,,:OprR,77,20044.5),,,,,,:S.intermediusHepG2,77,20044.6)TomokoSumitomo,TakuyaMaeda,HideakiNagamuneandHirokiKourai:BacterioclasticActionofaBis-QuaternaryAmmoniumCompoundagainstEscherichiacoli,BiocontrolScience,Vol.9,No.1,2,pp.1–9,2004.7),,,,,,,:,10,20045.8),,,,,:p53,10,20045.9):,,Vol.39,No.5,pp.285–290,20045.10):,,,pp.289–292,,20045.11),,:,31,Vol.IICa-2,20045.12),,,:gemini,31,Vol.IIDp-2,20045.13),,,:,31,Vol.IIDp-3,20045.14),,:4,4’-(1,8-Dioxyoctametamethylene)bis(1-alkylpyridiniumhalide)s,31,Vol.IIDp-4,20045.15),,,,,:,31,Vol.IIDp-7,20045.16),,,,:,31,Vol.IIDp-6,20045.17),,,:OmpE,31,Vol.IIDp-8,20045.18),,,,:,31,Vol.IIDp-9,20045.19),,,,:,31,Vol.IIDp-10,20045.20),,,:,31,Vol.IIDp-11,20045.21)RyokoBuma,TakuyaMaeda,YukoMarutaka,MasaharuKamei,HideakiNagamuneandHirokiKourai:Vectorialcapacityoflarvaepupaeandadultofhousefly(Muscadomestica)forEscherichiacoli0157:H7andthepossibilityoftransmissionfromsourcetohuman,MedicalEntomologyandZoology,Vol.55,No.2,pp.95–106,2004.22),,,,,,,:4,14,20046.23),,,,,,,,,,,,,:C,26,20046.24)Shin-ichiroMasunaga,HidekoNagasawa,MASAMITSUHIRAOKA,YOSHINORISAKURAI,YoshihiroUto,HitoshiHori,KENJINAGATA,MINORUSUZUKI,AKIRAMARUHASHI,YUKOKINASHIandKOJIONO:Applicabilityofthe2-Nitroimidazole-sodiumborocaptate-10BConjugate,TX-2060,asa10B-carrierinBoronNeutronCaptureTherapy,AnticancerResearch,Vol.24,No.5,pp.2975–2983,2004.25):JABEE,,Vol.62,No.7,p.47,20047.26)Shin-ichiroMasunaga,HidekoNagasawa,MasamitsuHiraoka,YoshinoriSakurai,YoshihiroUto,HitoshiHori,KenjiNagata,MinoruSuzuki,AkiraMaruhashi,YukoKinashiandKojiOno:Theusefulnessof2-nitroimidazole-sodiumborocaptate-10Bconjugatesas10B-carriersinboronneutroncapturetherapy,Appl.Radiat.Isot.,Vol.61,No.5,pp.953–958,2004.27)Cheng-ZheJin,HidekoNagasawa,MarikoShimamura,YoshihiroUto,SeiichiInayama,YoshioTakeuchi,L.KennethKirkandHitoshiHori:AngiogenesisinhibitorTX-1898:synthesisoftheenantiomersofstericallydiversehaloacetylcarbamoyl-2-nitroimidazolehypoxiccellradiosensitizers,Bioorganic&MedicinalChemistry,Vol.12,No.18,pp.4917–4927,2004.28)HideakiNagamune,KazutoOhkura,AkikoSukeno,GraemeCowan,TimothyJ.Mitchell,WataruIto,OokiOhnishi,KanakoHattori,MikiYamato,KatsuhikoHirota,YoichiroMiyake,TakuyaMaedaandHirokiKourai:Thehuman-specificactionofintermedilysin,ahomologofstreptolysinO,isdictatedbydomain4oftheprotein.,MicrobiologyandImmunology,Vol.48,No.9,pp.677–692,2004.29),,,,::,2004,20049.30),,:,63,20049.PDF(EDB)(Createdbyat22112717)—1—31)KazutoOhkura,HideakiNagamuneandHirokiKourai:Structuralanalysisofhumanspecificcytolysinintermedilysinaimingapplicationtocancerimmunotherapy,AnticancerResearch,Vol.24,No.5,pp.3343–3354,2004.32)HideakiNagamune,KazutoOhkura,KazunoriUmezu,HidekatsuShoujiandHirokiKourai:Acellmembranemodificationtechniqueusingdomain4ofintermedilysinforimmunotherapyagainstcancer,AnticancerResearch,Vol.24,No.5,pp.3367–3372,2004.33)HajimeAono,NobutakeTamai,DaisukeTatsumiandTakayoshiMatsumoto:AggregateStructureandRheologicalPropertiesofMercelizedCellulose/LiCl-DMAcSolution,JournalofSocietyofRheologyJapan,Vol.32,No.4,pp.169–177,2004.34)ZhouFei,TakuyaMaeda,HideakiNagamuneandHirokiKourai:Synthesisandantimicrobialcharacteristicsofnovelbiocides,1,1’-(decanedioyl)bis(4-methyl-4-alkylpiperadiniumiodide)swithageministructure,BiocontrolScience,Vol.9,No.3,pp.61–67,2004.35)HidekoNagasawa,HideyukiSasaki,YoshihiroUto,Shin-ichiKuboandHitoshiHori:AssociationoftheMacrophageActivatingFactor(MAF)PrecursorActivitywithPolymorphisminVitaminD-bindingProtein,AnticancerResearch,Vol.24,No.5c,pp.3361–3366,2004.36)CKohchi,HInagawa,MHino,MOda,KNakata,AyaYoshida,HitoshiHori,HTerada,KMakino,KTakiguchiandGenichiroSoma:Utilizationofmacrophagesinanticancertherapy:themacrophagenetworktheory,AnticancerResearch,Vol.24,No.5C,pp.3311–3320,2004.37),,,,:C,28,200410.38)HitoshiMatsuki,MichioYamanaka,HiroshiKamaya,ShojiKaneshinaandIssakuUeda:Preferentialpartitioningofunchargedlocalanestheticsintothesurface-adsorbedfilm,ColloidsandSurfacesB:Biointerfaces,Vol.38,No.1-2,pp.91–99,2004.39)HideakiNagamune,HisashiOhkuni,KazutoOhkura,TakuyaMaedaandHirokiKourai:Streptococcusmitis-derivedhumanplateletaggregationfactorsecretedbyanisolatefromaKawasakidiseasepatientisauniquememberofcholesterol-dependentcytolysin,The5thWorkshoponPore-formingToxins,Mainz,Germany,Oct.2004.40)GraemeCowan,HideakiNagamuneandTimothyMitchell:Thehuman-specificity