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硒的生物学特性与奶牛营养需要的研究进展黄静,黄克和(,210095):,,:;;:S81615:A:05295130(2010)080103031817Berzeliu(Selenium),,1957SchwartzFoltzE,,,1972Roetrueh,(GSHPx),1973,198820,,,111,,(GSHPx),30%~40%GSHPx,GSHPx[1]GSHPx,,[2]E12,,,THawkes[3]TB,TB,T(CTL),,,,H2O2:20100117:(1976),,John[4],,T,,,IgGIgM,Miroslav[5],,13(PHGPx),Stradaioli[6],PHGPx,,,,,[7],:,,[8](ID,ID,ID!),,(T3),,14,,,,,,,,,,∀103∀201042815,O-2HO.HOOH2O2,,P,DNA,1965,ShambergerRudolph,,[9],,,,,2,,,;,,,Se,,,[10]21Fokkink[11],,42dE,,,[12],300mg/kg[13]22,,,10~100d,E23,,,,,,24,TB,,,,,[14]25,,10%~20%,,,,;,E,,GSHPx;,005mg/L,005~010mg/L,9%,005mg/L,51%;,[15],[16]331,32,,,;020mg/kg,005~030mg/kg,20mg/kg;NRC(1998)030mg/kg,20mg/kg4∀104∀AnimalHusbandry&VeterinaryMedicine2010Vol42No8肖长赏1,凌红丽1,邢丹2,张艳平1,曾群平1(1.,266114;2.,210095),,,,SPFHI,111材料:20SPF20,,,SPF,:(LaSota)1000,200809001,1,,,,,,:[1]HuguesGuyot,ClaudeSaegerman,PascalLebreton.EpidemiologyoftraceelementsdeficienciesinBelgianbeefanddairycattleherds[J].JournalofTraceElementsinMedicineandBiology,2009,23:116123.[2]JerryW,Spears,WilliamP.Roleofantioxidantsandtraceelementsinhealthandimmunityoftransitiondairycows[J].TheVeterinaryJourna,l2008,176:7076.[3]HawkesWC,AmieHwang,ZeynepAlkan.TheeffectofseleniumsupplementationonDTHskinresponsesinhealthyNorthAmericanMen[J].JournalofTraceElementsinMedicineandBiology,2009,23:272280.[4]JohnJT,BruceAWatkins,IngridA.Schoenlein,Oxidizedlipiddepressescaninegrowth,immunefunction,andboneformation[J].JournalofNutritionalBiochemistry,2003,14:2431.[5]MiroslavStyblo,FeleciaSWalton,AnneW,eta.lActivationofsuperoxidedismutaseinseleniumdeficientmiceinfectedwithinfluenzavirus[J].JournalofTraceElementsinMedicineandBiology,2007,21:5262.[6]StradaioliG,SyllaL,MonaciM,eta.lPhospholipidhydroperoxideglutathioneperoxidaseinbullspermatozoaprovidesauniquemarkerinthequestforsemenqualityanalysis[J].Theriogenology,2009,72:9198.[7]RebeccaBS,FinnieAM,JulienWE,eta.lEffectofinvitroseleniumsupplementationonbovinespermmotility[J].Theriogenology,1980,5(13):357367.[8]KaurP.Effectofseleniuminducedoxidativestressonthecellkineticsintestisandreproductiveabilityofmalemice[J].Nutrition,2005,21(3):351357.[9]KimT,JungU,ChoDY,eta.l2methylselenocysteineinducesapoptosisthroughcaspaseactivationinHL260cells[J].Carcinogenesis,2001,22(4):559565.[10]CerriRLA,RutiglianoHM,LimaFS,eta.lEffectofsourceofsupplementalseleniumonuterinehealthandembryoqualityinhighproducingdairycows[J].Theriogenology,2009,71:11271137.[11]FokkinkWB,HillTM,BatemanHG,eta.lSeleniumyeastfordairycalffeeds[J].AnimalFeedScienceandTechnology,2009,153:228235.[12]KumaraN,GargaAK,DassaRS,eta.lSeleniumsupplementationinfluencesgrowthperformance,antioxidantstatusandimmuneresponseincalves[J].AnimalFeedScienceandTechnology,2009,153:7787.[13]WangC,LiuQ,YangWZ,eta.lEffectsofSeleniumyeastonrumenfermentation,lactationperformanceandfeeddigestibilitiesinlactatingdairycows[J].LivestockScience,2009,126:239244.[14]JavierInnateimmuneresponseofbovinemammaryglandtopathogenicbacteriaresponsibleformastitis[J].JournalofInfection,2007,4(54):399409.[15]PalmerRM,FerrigcAG.Nitricoxidereleaseaccountsforthebiologicalactivityofendotheliumderivedrelaxingfactor[J].Nutre,1987,27:524526.[16]BrozosCN,KiossisE,GeorgiadisMP.Theeffectofchlorideammonium,vitaminEandSesupplementationthroughoutthedryperiodonthepreventionofretainedfetalmembranes,reproductiveperformanceandmilkyieldofdairycows[J].LivestockScience,2009,124:210215.∀105∀2010428