系统生物学的研究现状及应用

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廖丹,,,,,,,,,;;;1,,,,,,,,,,[1],,[2],,,,[3],221,,[2],,,,complexityrobustness,,,,,22,,,,,23DNA:400715,(Reductionism),,,,,,,,,,,,DNARNA,,,,:!,,;∀;#,,,;∃,;%,,,3~5[6],231,,,,,,LeroyHood1,,[8]30,?9,LeroyHood430,9,9,16200,,,2&108&20075213ChinaPracMed,May2007,Vo.l2,No.13,,,Cytoscape;DNA,,ICAT()300,,232,[9]3:GeneBank,EMBLDDBJ,KGEE,,,,,KeioUniversity,(Mycoplasmagenitalium),3:∋(∋(∋(,∋(,,;∋(,,∋(;∋(:,;,,,;,,(GenomestoLifeGTL):,:!;∀;#;∃,(humanphysiomeproject,HPP):,:,,,,:!;∀;#Endotheliome;∃,(thedigitalhuman),ERATO(Systome),(NRV)[11],20024,,,,,,,,,,,,,,,,1.21),,2004,4(2):56.2vonBertalanffyL,GeneralSystemsTheory,GeorgeBraziller,NewYork,1968.3HiroakiKitano,Systemsbiology:Abriefoverview,Science;Mar1,2002,295:5560.4MitchellP.LevesqueandPhilipN.Benfey,Systemsbiology,CurrentBiology:179180.5ChaerkadyRaghothamaandAkhileshPandey,Absolutesystemsbiologymeasuringdynamicsofproteinmodifications,TRENDSinBiotechnology,2003:467470.6.,,2004:3134.7,.),,2004:281288.8EugeneJ.Davidov,JoanneM.Holland,EdwardW.MarpleandStephenNaylorAdvancingdrugdiscoverythroughsystemsbiology,drugdiscoverytoday,2003:1751830.9,,..10JeffreyL.Blanchard,BioinformaticsandSystemsBiology,rapidlyevolvingtoolsforinterpretingplantresponsetoglobalchange,J.L.Blanchard/FieldCropsResearch90(2004):117131.11,,.,,2004:101103.&109&20075213ChinaPracMed,May2007,Vo.l2,No.13

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