紫杉醇类似物的合成研究Ⅷ去甲二萜生物碱转化合成紫杉醇类似物的

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四川大学博士学位论文紫杉醇类似物的合成研究Ⅷ去甲二萜生物碱转化合成紫杉醇类似物的研究姓名:谢光波申请学位级别:博士专业:药物化学指导教师:王锋鹏20050423紫杉醇类似物的合成研究Ⅷ去甲二萜生物碱转化合成紫杉醇类似物的研究作者:谢光波学位授予单位:四川大学参考文献(70条)1.MCWani.HLTaylor.MEWall.P.Coggen,A.T.McphailPlantantitumoragents.Ⅵ.Theisolationandstructureoftaxol,anovelantileukemicandantitumoragentfromtaxusbrevifolia19712.综述参考文献部分2~73.RAHoltonMethodfropreparationoftaxol19904.徐亮紫杉醇类似物的合成研究.ⅥA.对映-贝壳杉烷型二萜转化成紫杉醇类似物中关键反应的研究.B.去甲二萜生物碱转化成紫杉醇类似物合成路线的研究[学位论文]博士20035.徐亮紫杉醇类似物的合成研究.ⅥA.对映-贝壳杉烷型二萜转化成紫杉醇类似物中关键反应的研究.B.去甲二萜生物碱转化成紫杉醇类似物合成路线的研究[学位论文]博士20036.QHChen.LXu.FPWangAnovelconversionofnorditerpenoidalkaloidsintoaconane-typediterpenes20027.SRam.REEhrenkauferAgeneralprocedureformildandrapidreductionofaliphaticandaromaticnitrocompoundsusingammoniumformateasacatalytichydrogentransferagent19848.HTakayama.SISakai.KYamaguchi.T.OkamotoThepartialsynthesisofisodelphinine1982(30)9.STakatsuto.NIkekawaShort-stepsynthesisofplantgrowth-promotingbrassinosteroids198410.HTakayama.SHasegawa.SISakai.J.Haginiwa,andT.OkamotoStructureelucidationofanewaconitealkaloid,15-α-hydroxyneoline198111.SKatayama.JHiramatsu.KAoe.M.YamauchiSynthesisof1-hydroxybicyclo[3.2.1]oct-3-en-2-onesbyacyloinrearrangementof1-methoxy-or1-tert-butyldimethylsilyloxy-bicyclo[2.2.2]oct-5-en-2-ones199712.QHChen.FPWangFurtherstudiesonthesynthesisof7,17-seco-norditerpenoidalkaloids2003(05)13.VBalogh.JCBeloeiletMFetizon:Synthesesdecardenolides-I197714.PMagnus.RLewis.FBennettSyntheticandmechanisticstudiesontheantitumorantibioticsesperamicinA1andcalicheamicinγ1.Oxidativefunctionalizationofthe13-ketobicyclo[7.3.1]tridecenediynecorestructure:Constructionoftheallylictrisulfidetrigger199215.EFujita.MOchiaiTerpenoids.Part40.Oxidativerearrangementofent-17-norkauran-16-onewithThallium(Ⅲ)Nitrateandsynthesisofent-9(8→15αH)abeo-kaurane197716.PAGunn.RMcCrindle.RGRoySynthesisofaneoatisiranne,theenantiomerofaketoneobtainedbytheacid-catalysedrearrangementofisophyllocladeneepoxide197117.XHLiang.HKDesai.BSJoshi.S.W.PelletierDemethylationofnorditerpenoidalkaloids199018.SWPelletier.KNIyer.CWJChangOxidativedegradationofresinacids197019.FPWang.QHChen.BGLiNovelsynthesisof12,13-seconorditerpenoidalkaloidsviasemipinacolrearrangementandreactionwithBr2-HOAc200120.DCaine.AABoncugnani.STChao.J.B.Dawson,andP.F.IngwalsonStereospecificsynthesisof6-c-10-dimethyl(γ-5-c')spiro[4.5]dec-6-en-2-oneanditsconversioninto(±)-α-vetispirene197621.JNBeMiller.REWing.GYMeyersThespecificdebenzylationofalkylatedcarbohydratesviabromination-hydrolysis196822.RWBinkley.DGHehemannAlight-initiatedprocessforrapiddebenzylationofcarbohydrates199023.MCWani.HITaylor.MEWall.P.Coggen,A.T.McphailPlantantitumoragents.Ⅵ.Theisolationandstructureoftaxol,anovelantileukemicandantitumoragentfromtaxusbrevifolia197124.RAHolton.CSomoza.HBKim.F.Liang,R.T.Biediger,P.D.Boatman,M.Shindo,C.C.Smith,S.Kim,Y.Suzuki,C.Tao,P.Vu,S.Tang,D.S.Zhang,K.K.Murthi,L.N.GentileandJ.H.LiuFirsttotalsynthesisoftaxol.1.FunctionalizationoftheBring199425.RAHolton.HBKim.CSomoza.F.Liang,R.T.Biediger,P.D.Boatman,M.Shindo,C.C.Smith,S.Kim,H.Nadizadeh,C.Tao,P.Vu,S.Tang,P.Zhang,K.K.Murthi,L.N.GentileandJ.H.Liu,Firsttotalsynthesisoftaxol.2.CompletionoftheCandDring查看详情199426.KCNicolaou.ZYang.JJLiu.H.Ueno,P.G.Nantermet,R.K.Guy,C.F.Claibome,J.Renaud,E.A.Couladouros,K.Paulvannan,E.I.SorensenTotalsynthesisoftaxol199427.SJDanishefsky.JJMasters.WBYoung.T.Link,L.B.Sngder,T.V.Magee,D.K.Jung,R.A.Isaacs,W.G.Bornmann,C.A.Alaimo,C.A.Coburn,andM.J.Digrandi,TotalsynthesisofbaccatinⅢandtaxol查看详情199628.PAWender.NFBadham.SPConway.P.E.Floreancig,T.E.Glass,C.Granicher,J.B.Houze,J.Janichen,D.Lee,D.G.Marquess,P.L.McGrane,W.Meng,T.P.Mucciaro,M.Muhlebach,M.G.Natchus,H.Paulsen,D.B.Rawlins,J.Satkotsky,A.J.Shuker,J.C.Suttoon,R.E.Taylor,andKThePinenepathtotaxanes.5.stereocontrolledsynthesisofaversatiletaxaneprecursor199729.PAWender.NFBadham.SPConway.P.E.Floreancig,T.E.Glass,J.B.Houze,N.E.Krauss,D.Lee,D.G.Marquess,P.L.McGrane,W.Meng,M.G.Natchus,A.J.Shuker,J.C.Sutton,andR.E.TaylorThepinenepathtotaxanes.6.Aconcisestereocontrolledsynthesisoftaxol199730.TMukaiyama.IShiina.HIwadare.H.Sakoh,Y.I.Tani,M.Hasegawa,andK.SaitohAsymmetrictotalsynthesisoftaxol199731.TMukaiyama.IShiina.HIwadare.M.Saitoh,T.Nishimura,N.Ohkawa,H.Sakoh,K.Nishimura,Y.I.Tani,M.Hasegawa,K.Yamada,andK.SaitohAsymmetrictotalsynthesisoftaxol1999(05)32.KMorihira.RHara.SKawahara.T.Nishimori,N.Nakamura,H.Kusama,andI.KuwajimaEnantioselectiveTotalSynthesisofTaxol199833.徐亮.王锋鹏抗癌药物紫杉醇的全合成-Nicolaou法全合成紫杉醇的剖析[期刊论文]-有机化学2001(7)34.陈巧鸿.王锋鹏抗癌药物紫杉醇的全合成--Holton合成紫杉醇路线的剖析[期刊论文]-天然产物研究与开发2001(3)35.黄化民紫杉醇全合成[期刊论文]-合成化学1998(3)36.TMukaiyama.IShiina.KSakata.T.Emura,K.Seto,andM.Saitoh,AnovelapproachtothesynthesisofTaxolAsynthesisofopticallyactive3,7-dibenzyloxy-4,8-di-t-butyl-dimethylsiloxy-5,5-dimethyl-6-p-methoxybenzyloxy-2-octanonebywayofstereoselectivealdolreactions199537.IShiina.HIwadare.HSakoh.Y.I.Tani,M.Hasegawa,K.Saitoh,andT.MukaiyamaStereocontrolledsynthesisoftheBCringsystemoftaxol199738.IShiina.HIwadare.HSakoh.M.Hasegawa,Y.I.Tani,andT.MukaiyamaAnewmethodforthesynthesisofbaccatinⅢ199839.I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