200911261200911262ØØØØØ200911263200-.3.2009112641.,400,100.2.3.200911265200911266::BB-12LA-5200911267ØØØØØ200911268Metchnikoff1910?200911269•••,2009112610?2009112611(FAO/WHOreport,Oct2001)2009112612ØØØØØ2009112613()\()()(\)200911261462009112615ØØØØØ2009112616ØØØ2009112617ØØØØ20091126182009112619ØØØØØ20091126202009112621————200911262201020304050601925293949592009112623200911262420091126252009112626ØvvvvØØ2009112627Ø“”Ø2009112628ØØØØØ2009112629ØBifi-dobacteriumOrlaJensen1924472ØØ20091126301,2,3,4,,5,6,7,PH.20091126311,2,3,4,,5,6,7,.20091126321,2,3,4,,5,6,7,B1B6B12K1220091126331,2,3,4,,5,6,7,20091126341,2,3,4,,5,6,7,20091126351,2,3,4,,5,6,7,20091126361,2,3,4,,5,6,7,2009112637355310541520102030405060CompletionofTripletherapySide-effectsingeneralDiarrheaPlaceboLA-5+BB-12**Persons(#)BB-12andLA-5on160adultsonstandardtripleantibiotictreatmentforeradicationofH.pyloriSheuetal.2002*20091126380510152025303540SheddingShedding%ofinfantsBB-12&Th-4555-24BB-12TH-480DBPCSaavedraetal.1994;Lancet344:1046-104920091126391.2.3.20091126406L.paracaseisubsp.paracasei4Shirota,L.caseiimmunitas,L.casei431,F-196Bifidobacterium4BB-12,BifidobacteriumEssensis,BB-5366Lactobacillusacidophilus4LA-5NCFM6Lactobacillusjohnsonii(4Lc-16Lactobacillusrhamnosus4LGG6Others:Reuteri,L.plantarum299v20091126411.2.3.4.