2013软组织与骨肿瘤分类第4版

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WHOclassificationoftumoursofsofttissueTNMclassificationofsofttissuesarcomas1Tumoursofsofttissue:IntroductionEpidemiologyEtiologyClinicalfeaturesImagingoftumoursofsofttissueGradingandstagingofsarcomas2AdipocytictumoursLipomaLipomatosisLipomatosisofnerveLipoblastomaAngiolipomaMyolipomaofsofttissueChondroidlipomaSpindlecell/pleomorphiclipomaHibernomaAtypicallipomatoustumourDedifferentiatedliposarcomaMyxoidliposarcomaPleomorphicliposarcoma3Fibroblastic/myofibroblastictumoursNodularfasciitisProliferativefasciitisandproliferativemyositisMyositisossificansandfibro-osseouspseudotumourofdigitsIschaemicfasciitisElastofibromaFibroushamartomaofinfancyFibromatosiscolliJuvenilehyalinefibromatosisInclusionbodyfibromatosisFibromaoftendonsheath软组织肿瘤的分类软组织肉瘤的TNM分类软组织肿瘤1例:介绍流行病学病因临床特点软组织肿瘤的影像学分级和分期的肉瘤2脂肪细胞肿瘤脂肪瘤脂肪瘤病神经脂肪瘤病脂肪母细胞瘤血管脂肪瘤软组织平滑肌脂肪瘤软骨样脂肪瘤梭形细胞/多形性脂肪瘤蛰伏脂瘤非典型性肿瘤去分化脂肪肉瘤黏液样脂肪肉瘤多形性脂肪肉瘤3纤维母细胞/肌纤维母细胞瘤结节性筋膜炎增生性筋膜炎、增生性肌炎骨化性肌炎和纤维骨性假瘤数字缺血性筋膜炎弹力纤维瘤婴儿纤维性错构瘤颈部纤维瘤病幼年性透明纤维瘤病包涵体病腱鞘纤维瘤DesmoplasticfibroblastomaMammary-typemyofibroblastomaCalcifyingaponeuroticfibromaAngiomyofibroblastomaCellularangiofibromaNuchal-typefibromaGardnerfibromaCalcifyingfibroustumourPalmar/plantarfibromatosisDesmoid-typefibromatosisLipofibromatosisGiantcellfibroblastomaDermatofibrosarcomaprotuberansExtrapleuralsolitaryfibroustumourInflammatorymyofibroblastictumourLow-grademyofibroblasticsarcomaMyxoinflammatoryfibroblasticsarcomaInfantilefibrosarcomaAdultfibrosarcomaMyxofibrosarcomaLow-gradefibromyxoidsarcomaSclerosingepithelioidfibrosarcoma4So-calledfibrohistiocytictumoursTenosynovialgiantcelltumour,localizedtypeTenosynovialgiantcelltumour,diffusetypeDeepbenignfibroushistiocytomaPlexiformfibrohistiocytictumourGiantcelltumourofsofttissue5Smooth-muscletumoursLeiomyomaofdeepsofttissueLeiomyosarcoma6Pericytic(perivascular)tumoursGlomustumoursMyopericytoma,includingmyofibromaAngioleiomyoma7Skeletal-muscletumoursDF乳腺型肌纤维母细胞瘤钙化性腱膜纤维瘤血管肌纤维母细胞瘤细胞性血管纤维瘤颈型纤维瘤加德纳纤维瘤钙化性纤维性肿瘤手掌/足底纤维瘤病韧带样纤维瘤病lipofibromatosis巨细胞纤维母细胞瘤隆突性皮肤纤维肉瘤胸膜孤立性纤维性肿瘤炎性肌纤维母细胞瘤低度恶性肌纤维母细胞肉瘤黏液炎性纤维母细胞肉瘤婴儿型纤维肉瘤成人纤维肉瘤黏液纤维肉瘤低度恶性纤维黏液肉瘤硬化性上皮样纤维肉瘤4所谓的纤维组织细胞肿瘤腱鞘巨细胞瘤,腱鞘巨细胞瘤局限型,弥漫型深丛状纤维组织细胞肿瘤良性纤维组织细胞瘤巨细胞瘤软组织5平滑肌肿瘤深部软组织平滑肌瘤平滑肌肉瘤6周(周)肿瘤血管球瘤肌周细胞瘤,包括肌纤维瘤血管平滑肌瘤7骨骼肌肿瘤RhabdomyomaEmbryonalrhabdomyosarcomaAlveolarrhabdomyosarcomaPleomorphicrhabdomyosarcomaSpindlecell/sclerosingrhabdomyosarcoma8VasculartumoursHaemangiomasEpithelioidhaemangiomaAngiomatosisLymphangiomaKaposiformhaemangioendotheliomaRetiformhaemangioendotheliomaPapillaryintralymphaticangioendotheliomaCompositehaemangioendotheliomaKaposisarcomaPseudomyogenichaemangioendotheliomaOtherintermediatevascularneoplasmsEpithelioidhaemangioendotheliomaAngiosarcomaofsofttissue9Chondro-osseoustumoursSoft-tissuechondromaExtraskeletalosteosarcoma10Gastrointestinalstromaltumours11NervesheathtumoursSchwannoma(includingvariants)MelanoticschwannomaNeurofibroma(includingvariants)PerineuriomaGranularcelltumourDermalnervesheathmyxomaSolitarycircumscribedneuromaEctopicmeningioma/meningothelialhamartomaNasalglialheterotopia横纹肌瘤胚胎性横纹肌肉瘤腺泡状横纹肌肉瘤多形性横纹肌肉瘤梭形细胞/硬化性横纹肌肉瘤8血管肿瘤血管瘤上皮样血管瘤血管瘤病淋巴管瘤卡波西样血管内皮瘤网状血管内皮瘤乳头状淋巴管瘤复合血管内皮瘤卡波济肉瘤pseudomyogenic血管内皮瘤其他中间血管肿瘤上皮样血管内皮瘤软组织肉瘤9骨软骨瘤软组织软骨瘤骨外骨肉瘤10胃肠道间质瘤11神经鞘瘤神经鞘瘤(包括变种)黑色素性神经鞘瘤神经纤维瘤(包括变种)神经束膜瘤颗粒细胞瘤皮肤神经鞘粘液瘤孤切神经瘤异位脑膜瘤/上皮错构瘤鼻神经胶质异位BenignTritontumourHybridnervesheathtumoursMalignantperipheralnervesheathtumourMalignantgranularcelltumourEctomesenchymoma12TumoursofuncertaindifferentiationAcralfibromyxomaIntramuscularmyxomaJuxta-articularmyxomaDeep(aggressive)angiomyxomaPleomorphichyalinizingangiectatictumourofsoftpartsEctopichamartomatousthymomaAtypicalfibroxanthomaAngiomatoidfibroushistiocytomaOssifyingfibromyxoidtumourMyoepithelioma/myoepithelialcarcinoma/mixedtumourHaemosideroticfibrolipomatoustumourPhosphaturicmesenchymaltumourSynovialsarcomaEpithelioidsarcomaAlveolarsoftpartsarcomaClearcellsarcomaofsofttissueExtraskeletalmyxoidchondrosarcomaMalignantmesenchymomaDesmoplasticsmallroundcelltumourExtrarenalrhabdoidtumourPEComaIntimalsarcoma13Undifferentiated/unclassifiedsarcomasWHOclassificationoftumoursofbone良性肿瘤的Triton混合神经鞘肿瘤恶性外周神经鞘瘤恶性颗粒细胞瘤ectomesenchymoma12肿瘤的不确定分化肢端纤维黏液瘤肌内黏液瘤关节旁粘液瘤深(“侵略”)性多形性透明变性血管扩张性肿瘤软组织异位性错构瘤性胸腺瘤非典型纤维黄色瘤血管瘤样纤维组织细胞瘤骨化性纤维黏液瘤肌上皮瘤/肌上皮癌/混合瘤haemosideroticfibrolipomatous肿瘤间质瘤phosphaturic滑膜肉瘤上皮样肉瘤腺泡状软组织肉瘤软组织透明细胞肉瘤骨外黏液样软骨肉瘤恶性间叶瘤促结缔组织增生性小圆细胞肿瘤肾外横纹肌样瘤临床特点内膜肉瘤13未分化/未分类肉瘤骨肿瘤的分类TNMclassificationofbonesarcomas14Tumoursofbone:Introduction15ChondrogenictumoursOsteochondromaChondromas:enchondroma,periostealchondromaChondromyxoidfibromaOsteochondromyxomaSubungualexostosisandbizarreparostealosteochondromatousproliferationSynovialchondromatosisChondroblastomaChondrosarcoma(gradesI-III)includingprimaryandsecondaryvariantsandperiostealchondrosarcomaDedifferentiatedchondrosarcomaMesenchymalchondrosarcomaClearcellchondrosarcoma16OsteogenictumoursOsteomaOsteoidosteomaOsteoblastomaLow-gradecentralosteosarcomaConventionalosteosarcomaTelangiectaticosteosarcomaSmallcellosteosarcomaParostealosteosarcomaPeriostealosteosarcomaHigh-gradesurfaceosteosarcoma17FibrogenictumoursDe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