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,(,710034):;[]R573[]A[]10052541X(2008)042197206,,,,,,,,,,,,1,;;,,2080,CCD,3851070m,125165m,,,(ERCP)2211()212(1):,,,EMR()ESD()EST(),710d,NSAIDs23d,2w,(2):68h,4h23d,(3):15min2%4%,(4):,15min015mg10mg,7912008204,,,[1]3,,,,,,[2],,,,:,;;();,;()4411,,,,,412,,,,,(1),,20cm,,,,,,,,,,()2,,,(1)1(2),,,,8912008204,413,,()(),,,,,,(2)2,,,,,,,,,,,,,,,,,,,,,,,,,,,,,414,,,,()4159912008204,,416,,,4,4%(10%),1,,,,,,,,4172,,,,,,2495%,,418,,,;;,;,,,,,,,,,,/,()()419,2,,,,,,,,(IDUS),4110,,,,,,,,12%012013%;,13%,;;013%;DNA,,,,10%N2[3]4111(Narrowbandimaging,NBI),,,NBINBI,,,,,,Bar2rett[4]00220082044112,CCD,60170,,,,NBI4113,,,,1h,,5;;;;60.1%,01000501003%,,,[5,6],:,,,,,,,,,,,,;,,,,,,7,,,10%(),5075%,50%200510409,513137%,8158%,19871990,,25588,94119%,70%,III-IV549153%13101%,20%510%,,,[7]:1528%[8],(Barrett)Barrett810%,,1022008204,[910],,,,,,[11,12],,,,[13],,2%817%,[14]1550,[15],,[16],(high2resolutionendoscopy)[17](fluorescenceendoscopy)[18](opti2calcoherencetomography,OCT)(confocallaserscanningmicroscopy)[19](capsuleendoscopy)[20],[1]REYJR,AXONA,BUDZYNSKAA,etal1GuidelinesoftheEuro2peanSocietyofGastrointestinalEndoscopy(E.S.G.E.).Antibiot2icProphylaxisforGastrointestinalEndoscopy[J]1Endoscopy,1998,30:3181[2]DOOLEYCP,LARSONAW,STACENH,etal.Double2contrastba2riummealanduppergastrointestinalendoscopy:acomparativestudy[J]1AnnInternMed,1984,101:538.[3]CANTOMI1Stainingingastrointestinalendoscopy:thebasics[J]1E2ndoscopy,1999,31:4791[4],,,1(NBI)[J]1,2007,24:2341[5]CAPPELLMS,COLONVJ,SIDHOMOA1Astudyofeightmedicalcentersofthesafetyandclinicalefficacyofesophagogastroduodenos2copyin83pregnantfemaleswithfollow2upoffetaloutcomewithcomparisontocontrolgroups[J]1AmJGastroenterol,1996,91:3481[6]CAPPELLMS,HUHCH1Astudyofthesafetyandclinicalefficacyofesophagogastroduodenoscopyafteresophageal,gastric,orduode2nalsurgeryin60patients[J]1AmJGastroenterol,1995,90:12681[7]SONNENBERGA,EL2SERAGHB1Economicaspectsofendoscopicscreeningforintestinalprecancerousconditions[J]1GastrointestEn2doscClinNorthAm,1997,7:1651[8]SANDLERRS,NYRENO,EKOBOMA,etal1Theriskofesophage2alcancerinpatientswithachalasia:apopulation2study[J]1JAMA,1995,274:13591[9]CAMERONAJ,LOMBOYCT,PERAM,etal1AdenocarcinomaoftheesophagogastricjunctionandBarrettsesophagus[J]1Gastro2enterology,1995,109:15411[10]TYTGATGN1Doesendoscopicsurveillanceinesophagealcolumnarmetaplasia(Barrettsesophagus)haveanyrealvalue[J]1Endosco2py,1995,27(1):191[11]STOLTEM1Clinicalconsequencesoftheendoscopicdiagnosisofgastricpolyps[J]1Endoscopy,1995,7:321[12]KAMIYAT,MORISHITAT,ASAKURAH,etal1Long2termfollow2upofstudyongastricadenomaanditsrelationtogastricprotrudedcarcinoma[J]1Cancer,1982,50:24941[13]SJOBLOMSM,SIPPONENP,JARVINENH1Gastroscopicfollow2upofperniciousanaemiapatients[J]1Gut,193,34:281[14]OFFERHAUSGJA,TERSMETTEAC,GIARDIELLOFM,etal1Ev2alu2ationofendoscopyforearlydetectionofgastric2stumpcancer[J]1L2an2cet,1993,340:331[15]TYTGATGNJ1UPPERGASTROINTESTINALENDOSCOPY1Text2bookofgastroenterology[M]1Chapter1381[16]POTCHENEJ1Prospectsforprogressindiagnosticimaging[J]1JIn2ternMed,2000,247(4):4111[17]NELSONDB,BLOCKKP,BOSCOJJ,etal1Highresolutionandhigh2magnificationendoscopy(technologystatusevaluationreport[J])1GastrointestEndosc,2000,52:8641[18]NAMIHISAA,MIWAH,WATANABEH,etal1Anewtechnique:light2inducedfluorescenceendoscopyincombinationwithparma2copendoscopy[J]1GastrointestEndosc,2001,53:3431[19]INOUEH,IGARIT,NISHIKAGET,etal1Anovelmethodofvirtualhistopathologyusinglaser2scanningconfocalmicroscopyin-vitrowithuntreatedfreshspecimensfromthegastrointestinalmucosa[J]1En2doscopy,2000,32(6):439.[20]IDDANG,MERONG,GLUKHOVSKYA,etal1Wirelesscapsuleendoscopy[J]1Nature,2000,405:4171(:2008205215)2022008204