纳米羟基磷灰石的制备 范新健

纳米羟基磷灰石的制备姓名：范新健班级：10级应化一班目录•引言•羟基磷灰石的制备及拓展•参考文献引言仿生合成羟基磷灰石是组成人体骨骼和牙齿的重要组成部分，HAP是一种生物活性材料，具有良好的生物相容性、生物活性和生物稳定性，广泛应用于生物医药，催化和污水处理等领域。纳米羟基磷灰石在其功能上有一定的特性，如可以对一些肿瘤具有抑制作用,可以作为药物缓释材料抗生素、抗炎类等药物缓释载体，并且还可以作为某些化学反应的催化剂。•纳米HAP的制备方法主要有共沉淀法、水热法、溶胶-凝胶法、仿生合成和溶剂热法等。•由水热法合成均匀的不同纵横比和表面性质的F-替代HAP纳米管。少量3%F-加入HAP可以得到单晶纳米管。在合成单晶纳米管过程中加入PEG和油酸可以得到双亲性HAP纳米管。纳米羟基磷灰石的制备合成方法4ml油酸和0.5g十八胺/0.5gPEG(20000,MW)溶入16ml乙醇+Ca(NO3)2.4H2O（0.5g/7.5ml去离子水）NaF（0.003-0.025g/5ml去离子水）Na3PO4.12H2O（0.5g/7.5ml去离子水）搅拌十分钟，放入40ml高压釜中，90-150oC/200-220oC，十小时单晶F取代HAP纳米管主要内容：ThisisthereportonthefabricationofthehierarchicallynanostructuredHAPhollowspheresassembledfromnanorods.实验部分CaCl2(0.110g),C4H4O6KNa.4H2O(0.282g),NaH2PO4(0.094g)加入混合溶剂（DMF11ml/去离子水4ml)搅拌30分钟,然后将混合液转入20ml高压釜中，200oC煅烧2小时。产物离心，洗涤，在60oC烘干。Ca(NO3)2·4H2O+(NH4)2HPO4Ca/P=1.67,PH=10-11HAP加入碳酸氢铵喷雾干燥hollowhydroxyapatitemicrospheresCaNO3·4H2O和KH2PO4为前驱体用溶胶-凝胶法合成六角形的纳米棒状羟基磷灰石。氨水调PH=9。HA凝胶在60oC烘干并在不同温度下煅烧300oC-700oC。得到直径为70-90nm，长为400-500nm的羟基磷灰石纳米棒。其他制备方法实验部分1MCaNO3·4H2O去离子水0.67MKH2PO4去离子水逐滴的加入Ca/P=1.67氨水调PH=9，搅拌1h,室温下陈化48h,60oC烘干，300-700oC煅烧羟基磷灰石参考文献SupportedSilver-Nanoparticle-CatalyzedHighlyEfficientAqueousOxidationofPhenylsilanestoSilanolsTakatoMitsudome,ShusukeArita,HaruhikoMori,TomooMizugaki,KoichiroJitsukawa,andKiyotomiKaneda*Angew.Chem.Int.Ed.2008,47,7938–7940GoldSupportedonHydroxyapatiteasaVersatileMultifunctionalCatalystfortheDirectTandemSynthesisofIminesandOximesHaoSun,Fang-ZhengSu,JiNi,YongCao,*He-YongHe,andKang-NianFanAngew.Chem.Int.Ed.2009,48,4390–4393SolvothermalSynthesisandCharacterizationofHierarchicallyNanostructuredHydroxyapatiteHollowSpheresMing-GuoMa*[a]andJie-FangZhu[b][a]CollegeofMaterialsScienceandTechnology,BeijingForestryUniversity,Beijing100083,P.R.ChinaFax:[phone]E-mail:[e-mail][b]DepartmentofMaterialsChemistry,TheÅngströmLaboratory,UppsalaUniversity,Uppsala75121,SwedenEur.J.Inorg.Chem.0000,0–0Sol–gelsynthesisandcharacterizationofhydroxyapatitenanorodsSanoshKunjalukkalPadmanabhana,b,AvinashBalakrishnana,b,Min-CheolChub,YongJinLeea,TaikNamKima,Seong-JaiChob,∗aDepartmentofInformationandElectronicMaterialsEngineering,CollegeofEngineering,PaichaiUniversity,Daejeon302-735,RepublicofKoreabDivisionofMetrologyforEmergingTechnology,KoreaResearchInstituteofStandardsandScience,1Doryong-Dong,Yuseong-Gu,Daejeon305-340,RepublicofKoreaParticuology7(2009)466–470PreparationandcharacterizationofhollowhydroxyapatitemicrospheresbyspraydryingmethodRuixueSuna,YupengLub,*,KezhengChenaaCollegeofMaterialsScienceandEngineering,QingdaoUniversityofScienceandTechnology,Qingdao266042,ChinabSchoolofMaterialsScienceandEngineering,ShandongUniversity,Jinan250061,ChinaMaterialsScienceandEngineeringC29(2009)1088–1092AnEffectiveMorphologyControlofHydroxyapatiteCrystalsviaHydrothermalSynthesisIne´sS.Neira,YuryV.Kolen’ko,OlegI.Lebedev,GustaafVanTendeloo,HimadriS.Gupta,FranciscoGuitia´n,andMasahiroYoshimuraCrystalGrowth&Design,Vol.9,No.1,2009467姓名：范新健学号：1008104016班级：10级应化一班