稳定的低粘度油包水体系 百好博

AnewmethodtopreparelowviscositybutstableW/Osystem一种制备低粘度稳定油包水体系的新方法CS-PPshanghaiLabPage|2Background研究背景LowviscosityW/Osystemisdifficulttomake，especiallyforpowdercontainedformulaslikesunscreenlotion(shake-shakeformula)andlowviscosityliquidfoundation.Themainreasonisnoteasytostabilize:oilseparationorpowdersedimentationalwaysoccurs.低粘度W/O含粉体系，如防晒(shake-shake配方)，低粘度粉底液等，通常遇到的最大问题是离心出油或者粉沉积，体系难以稳定.Twomethodshavebeenstudiedtargetingtothistopic:对文献和经验中的两种解决办法进行了研究：1.Stabilizerslikefumedhydrophobicsilicaorhydrophobicbentonitewasstudiedandscreened,butitcanonlygetstableviscositynolessthan5000cps.使用疏水的硅石或者膨润土。根据反复测试和筛选，可稳定的最低粘度为5000－6000cps2.ApatentfromBeiersdorf(US7138128B2)claimedthatcationicpolymercanimprovestabilityoflowviscosity,highwatercontentW/Osystem,buttheresultalsoshowstheloweststableviscosityisabove5000cps.Beiersdorf的一篇专利宣称使用阳离子聚合物可以帮助稳定较低粘度的油包水体系，但是同样，最低的粘度还是在5000－6000cpsPage|3FindingsandStudies发现和研究FindingsandStudies发现和研究Tocheckthepropertiesofsmallmocularweightcationicsurfactants(Varisoft®PATC,palmitamidopropyltrimoniumchlorideforexample)inW/Osystem.根据在实验中的意外发现：阳离子表面活性剂（以VarisoftPATC棕榈酰胺丙基三甲基氯化铵为代表）可以降粘的同时提高稳定性，于是对以下三类体系进行研究，这三类体系涵盖了所有油包水的应用情况ThreemainW/Osystemsarestudeid:主要研究的油包水体系1.WithsuperfinedpowderslikeTiO2orZnO超细的钛白粉和氧化锌——防晒产品2.WithpigmentspowderslikeTiO2颜料级的钛白粉——粉底产品3.Withoutanypowder不含粉的体系——普通产品Page|4NanoTiO2withVarisoftPATC超细TiO2+PATC的体系Formula1％AABILEM90乳化剂2.0TEGOSOFTDEC碳酸二乙基己酯7.0DC345环硅烷17.0TEGOSUNTDEC45(TiO2oildispersion)14.0BWater水To100Glyerin甘油5.0VARISOFTPATCxNaCl氯化钠1.0Preservative防腐剂q.s.X00.51.02.0Viscositympa.s1184980437.342.7Centrifugaltest，3000rpm5minOOKOKW10minOOKOKW15minOOOW30minOOOWHeatstability45℃2weeksOOKcoarseWPATChasanoptimumamountinthissystem,atacertainrange,viscositycanbeloweredbutsuspendingstabilityisimproved!Thisfindingisveryinteresting.试验证实，PATC有一个最适添加量，在此用量下PATC不仅可以（使含粉体系）降粘,同时还可以提高体系的稳定性O:oilout;W:waterout分层破乳Page|5Microstructure(10X10)withdifferentPATCconcentrations100倍下的显微照片EmulsionparticlesarelargerwithPATC=0原始配方乳化颗粒较大WithPTACincreased(from0.5%to1%)，particlessizeisgettingsmallerandstabilityimproved加入0.5%PTAC后，乳化颗粒明显减小，体系的稳定性也有所提高With2%PTAC,itshowsinhomogeneousandamultipleemulsionoccurs.DuetothebrokenHLBsystem.随着PTAC添加量的进一步增加，原有HLB值系统被破坏，微观结构显示了界面混乱以及多重乳液的出现X=0X=1X=2X=0.5Page|6ComparewithotherO/Wemulsifiers和其它HLB值较高的乳化剂相比较EmulsifierblankPATCPLFlakeXL80SBZViscositympa.s1184980140814181173Centrifugationtest，离心测试1000rpm10minOiloutOKOilout出油OKOK20minOiloutOKOilout出油OKOK30minOiloutOKOilout出油Oilout出油Oilout出油BasedonFormula1，0.5%PATCwassubstitutedbyPLFlake(GMSSE,anionic)，AbilcareXL80(nonionic)andREWOPOLSBZ(anionic).Resultsareasfollows:在配方1基础上，将0.5%PATC换成TEGINPLFlake(自乳化单甘酯)，ABILCareXL80（硅油改性的非离子水包油乳化剂），以及REWOPOLSBZ（月桂基磺基琥珀酸盐），研究这些不同离子性的亲水乳化剂对W/O含粉体系离心稳定性的影响。Comparewithotherhydrophilicemulsifier,cationicemulsifiershowsoutstandingsuspensionabilityforW/Opowderysystem阳离子乳化剂与其它乳化剂相比，对W/O含粉体系的降粘和悬浮稳定性改善最明显Page|7Dispersingeffectbydifferentsurfactants对疏水处理钛白粉的分散性比较123450.5%Surfactants+water+TEGOSUNTDEC451VarisoftPATC棕榈酰胺丙基三甲基氯化铵2ABILCareXL80硅油改性的非离子水包油乳化剂3REWOPOLSBZ月桂基磺基琥珀酸盐4PLFlake自乳化单甘酯5Blank空白AbovepictureshowsonlyPATChelpthedispersionoftestedhydrophobictreatedTiO2powders.图片结果显示只有PATC对当前测试的疏水改性超细钛白粉有较好的分散作用，这进一步证实PATC和粉体之间的相互作用。Page|8lowercontentsuperfinedTiO2system在较低含量超细粉体系中的情况Formula2％AABILEM90乳化剂2.0TEGOSOFTDEC碳酸二乙基己酯9.0DC345环硅烷14.0TEGOSUNTDEC4510.0BWaterTo100Glyerin5.0VARISOFTPATCxNaCl1.0preservativeq.s.Xvalue00.250.5Viscositympa.s1088714.710.7Centrifugaltest，1000rpm10minOiloutOKWaterout20minOiloutOKWaterout30minOiloutOKWateroutComparedwithFormula1,TEGOSUNTDEC45decreasedfrom14%to10%TDEC45的含量从14％降至10，相当于粉量从6.3%降至4.5%。Lessnanopowderadded,lesscationicemulsifierneeded含粉量降低，PATC的最适用量随之降低ItseemsPATCwasabsorbedbyTiO2powders.显示PATC会被钛白粉消耗。Page|9ComparedwithF3，F4haslowerviscosityandbetterstability.和配方F3相比，F4的粘度更低且稳定性更好Afteraddingmorewater,thesystemcanbestableataround2000mpa.s(F6)，muchbetterthanF5,whichisunstableevenwith3000mpa.s.加水增稠后，F6可通过稳定性测试，F5即使粘度更高但是不稳定StablelowviscosityW/OsystemwithnanoTiO2纳米TiO2的低粘度稳定W/O体系％Formula3Formula4Formula5Formula6AABILEM902.02.02.02.0TEGOSOFTDEC8.08.05.05.0DC34511.011.09.09.0TEGOSUNTDEC4514.014.014.014.0BWater59596464Glyerin5.05.05.05.0VARISOFTPATC00.500.5NaCl1.01.01.01.0preservativeq.s.q.s.q.s.q.s.Viscosity（sp62,30rpm）1877mpa.s1173mpa.s3157mpa.s2165mp.sCentrifugal(3000rpm,30min)OiloutLessoiloutOiloutOKGraphPage|10DifferentnanoTiO2（solidpowder）超细钛白粉干粉的情况Formula7(%)Formula8(%)AABILEM902.02.0TEGOSOFTDEC8.76.2DC3458.06.5NanoTiO2（MT100-TV）6.36.3BWater69.072.5Glyerin5.05.0VARISOFTPATC00.5NaCl1.01.0preservativeq.s.q.s.Viscosity粘度（sp62,30rpm）4682mpa.s4160mpa.sCentrifugal(3000rpm,30min)离心检验Oilout，pigmentsedimentation出油，出粉OKComparetoformula7,formula8havebettersuspendstabilityatsameviscosity,duetocationicaddition.和配方7相比，配方8具有在相同的粘度下具有合格的稳定性Page|11WithnanoZnOpowder超细氧化锌Formula9(%)Formula10(%)AABILEM902.02.0TEGOSOFTDEC8.78.7DC3458.08.0TEGOSUNZ8006.36.3BWater69.069.0Glyerin5.05.0VARISOFTPATC00.5NaCl1.01.0preservativeq.s.q.s.Viscosity(sp62,30rpm)6144mpa.s2410mpa.sCent