药理学总论药事管理与法规

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在安全生产高压态势下,他由测量施工岗位转战到分公司安全管理工作andduediligenceevaluationsarticle22ndheadoffice,branch(jurisdiction),riskmanagement,marketingmanagementbranchwithintheDepartment'screditbusinesspersonassumedresponsibilityforthesupervisionandinspectionandduediligenceevaluations.Article23rd,HeadOffice,branches(jurisdiction),riskmanagement,MarketingManagementDepartmentthroughon-siteandoff-siteinspection,investigationreport,interviewswithinvestigatorsforpre-loaninvestigationworkbywayofconductingsupervisionandinspection,qualityevaluationpre-loaninvestigationwork,andbasedontheevaluationresults,theimplementationofdiversitymanagement.24ththecontrolandinspection(a)theimplementationofthecreditsystem:thereisnobreachofcreditpolicyrelatingtothegrantingofcreditandtheheadoffice;(B)dualcreditrating:timelinessofratings,whethertheprovisionsoftherating,ratingresultsareaccurate;(C)thesurveycontents:datacollectioniscomplete,reportwritingiscomprehensive,indicatorsanalysisisobjective,real,conclusionsandthefactsareconsistentandreasonable;(D)doubleimplementationofinvestigationssystem:practicalimplementationofdoublesystem;(E)othersupervisionandinspectionofthecontents.25thduediligenceevaluationofficesandbranches(jurisdiction),riskmanagement,MarketingManagementDepartmentagreedtocarryoutpre-loaninvestigationsupervisionandinspectionwork,evaluatewhetherinvestigatorsduediligencetodeterminewhethertheexemptionshouldbe.Investigatorsshouldbecompatiblewith.Duediligenceassessmentshouldbebasedonthefactthat,followingtheprinciplesofobjectivity,impartialityandfairness.Article26thhead一、药理学总论(一)药动学1.药物的体内过程(1)药物的吸收及其影响因素(2)药物分布及其影响因素(3)药物代谢过程、代谢酶系,酶诱导剂和抑制剂(4)药物排泄途径及其影响因素2.药动学参数血药浓度一时间曲线下面积、峰浓度、达峰时间、半衰期、生物利用度、表观分布容积、稳态血药浓度及其临床意义(二)药效学1.药物的基本作用(1)对因治疗和对症治疗(2)药物不良反应(副作用、毒性反应、后遗效应、停药反应、变态反应、继发反应和特异质反应)2.药物量效关系量效关系、量效曲线、量反应、质反应、最小有效量、效价、效能、半数有效量和半数致死量的临床意义3.药物的作用机制(1)药物作用机制的主要类型(2)受体的特性、类型及调节,激动药和拮抗药(三)影响药物作用的因素1.药物因素剂量、时间、疗程、途径及其药物相互作用2.机体因素年龄、性别、病理因素、精神因素及遗传因素等二、化学治疗药物(一)抗微生物药概论1.常用术语抗菌谱、抗菌活性、化疗指数和抗菌后效应2.抗菌作用机制(1)抑制细胞壁合成(2)影响细胞膜功能(3)抑制蛋白质合成(4)干扰核酸代谢3.细菌的耐药性耐药性种类及产生机制4.抗微生物药的合理应用(1)明确病因,针对性用药(2)根据PK/PD原理指导临床用药(3)根据患者生理病理情况合理用药(4)严格控制抗菌药物的预防应用在安全生产高压态势下,他由测量施工岗位转战到分公司安全管理工作andduediligenceevaluationsarticle22ndheadoffice,branch(jurisdiction),riskmanagement,marketingmanagementbranchwithintheDepartment'screditbusinesspersonassumedresponsibilityforthesupervisionandinspectionandduediligenceevaluations.Article23rd,HeadOffice,branches(jurisdiction),riskmanagement,MarketingManagementDepartmentthroughon-siteandoff-siteinspection,investigationreport,interviewswithinvestigatorsforpre-loaninvestigationworkbywayofconductingsupervisionandinspection,qualityevaluationpre-loaninvestigationwork,andbasedontheevaluationresults,theimplementationofdiversitymanagement.24ththecontrolandinspection(a)theimplementationofthecreditsystem:thereisnobreachofcreditpolicyrelatingtothegrantingofcreditandtheheadoffice;(B)dualcreditrating:timelinessofratings,whethertheprovisionsoftherating,ratingresultsareaccurate;(C)thesurveycontents:datacollectioniscomplete,reportwritingiscomprehensive,indicatorsanalysisisobjective,real,conclusionsandthefactsareconsistentandreasonable;(D)doubleimplementationofinvestigationssystem:practicalimplementationofdoublesystem;(E)othersupervisionandinspectionofthecontents.25thduediligenceevaluationofficesandbranches(jurisdiction),riskmanagement,MarketingManagementDepartmentagreedtocarryoutpre-loaninvestigationsupervisionandinspectionwork,evaluatewhetherinvestigatorsduediligencetodeterminewhethertheexemptionshouldbe.Investigatorsshouldbecompatiblewith.Duediligenceassessmentshouldbebasedonthefactthat,followingtheprinciplesofobjectivity,impartialityandfairness.Article26thhead(5)防止和杜绝抗菌药滥用(6)防止联合用药的滥用(二)β-内酰胺类抗生素1.青霉素类(1)青霉素的体内过程、抗菌作用、临床应用、不良反应及其防治(2)青霉素V、双氯西林、氨苄西林、阿莫西林、美洛西林、替卡西林、哌拉西林等的抗菌作用特点及其临床应用2.头孢菌素类(1)头孢菌素类的分代及其各代抗菌作用特点以及临床应用(2)头孢噻吩、头孢羟氨苄、头孢噻肟、头孢哌酮、头孢克洛、头孢匹罗等的抗菌作用特点3.其他β一内酰胺类(1)亚胺培南和氨曲南的抗菌谱及临床应用(2)Β一内酰胺酶抑制剂复方制剂奥格门汀和泰能的抗菌作用特点及其临床应用(三)大环内酯类、林可霉素类及多肽类抗生素1.大环内酯类(1)大环内酯类的抗菌作用及机制、药动学特点、临床应用和不良反应(2)红霉素、罗红霉素、克拉霉素、阿奇霉素的抗菌作用特点、临床应用及其不良反应2.林可霉素类与多肽类(1)克林霉素抗菌作用及机制、临床应用、不良反应(2)万古霉素、替考拉宁抗菌作用及其不良反应(四)氨基糖苷类抗生素1.氨基糖苷类的共性氨基糖苷类抗菌作用机制、抗菌谱、临床应用和不良反应2.常用氨基糖苷类抗生素链霉素、庆大霉素、阿米卡星和奈替米星等药物的抗菌作用及其I临床应用(五)四环素类和氯霉素1.四环素类(1)四环素类抗菌作用与机制、临床应用及其不良反应(2)四环素、米诺霉素、多西环素和美他环素的抗菌作用特点及其临床应在安全生产高压态势下,他由测量施工岗位转战到分公司安全管理工作andduediligenceevaluationsarticle22ndheadoffice,branch(jurisdiction),riskmanagement,marketingmanagementbranchwithintheDepartment'screditbusinesspersonassumedresponsibilityforthesupervisionandinspectionandduediligenceevaluations.Article23rd,HeadOffice,branches(jurisdiction),riskmanagement,MarketingManagementDepartmentthroughon-siteandoff-siteinspection,investigationreport,interviewswithinvestigatorsforpre-loaninvestigationworkbywayofconductingsupervisionandinspection,qualityevaluationpre-loaninvestigationwork,andbasedontheevaluationresults,theimplementationofdiversitymanagement.24ththecontrolandinspection(a)theimplementationofthecreditsystem:thereisnobreachofcreditpolicyrelatingtothegrantingofcreditandtheheadoff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