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脱羟基在有机反应中的应用最近遇到不少虫友在有机交流版发帖求助和询问关于脱羟基反应,在这里我给大家总结一下脱羟基反应类型,希望对大家有用.脱羟基反应继Zn-Hg浓盐酸还原和黄明龙还原羰基到亚甲基的另一种合成亚甲基的方法,在有机合成中有着重要的作用,就羟基的还原的反应方法,本人总结如下,纯属个人愚见,欢迎大家积极讨论和补充.1.Et3SiH/TFAorPh3SiH/TFA2.Pd/C,H23.LiAlH4,AlCl3三氯乙酸4.NaBH4/TFA;Sodiumborohydrideintrifluoroaceticacidreducesdiarylmethanolsandtriarylmethols;tothecorrespondingdiarylmethanesandtriarylmethanesinexcellentyield.5.HISomehydoxylgrouphasbeenreplacedbyhydrogenbyrefluxingwithHIacid6.SmI2SynthesisofalkylpyridinederivativesbySmI2mediateddeoxygenationofpyridinemethanolderivatives7.TMSCl/NaITMSIinMeCNselectivelyreducesmoderatelyelectrondeficienttotheanalogoustoluenes;otherreductionsensitivefunctionalgroupssuchasketones,aldehyde,nitrile,andnitroareunaffected.8.Othermethods9.theconversionofhydroxylforhydrogenation[Lasteditedbyxiaopengson2011-6-30at15:09]