GuidelineforManageMentofPostMealglucoseWebsiteThisdocumentwillbeavailableat@med.usyd.edu.auOtherIDFpublications,includingGuideforGuidelines,areavailablefrom:InternationalDiabetesFederation,AvenueEmiledeMot19,B-1000Brussels,Belgium.communications@idf.orgAcknowledgmentsandsponsors’dualityofinterestThisactivitywassupportedbyunrestrictededucationalgrantsfrom:•AmylinPharmaceuticals•EliLillyandCompany•LifeScan,Inc.•Merck&Co.Inc•NovoNordiskA/S•RocheDiagnosticsGmbH•RochePharmaceuticalsThesecompaniesdidnottakepartinthedevelopmentoftheguideline.However,theseandothercommercialorganizationsonIDF’scommunicationslistwereinvitedtoprovidecommentsondraftversionsoftheguideline(seeMethodology).CopyrightAllrightsreserved.NopartofthispublicationmaybereproducedortransmittedinanyformorbyanymeanswithoutthewrittenpriorpermissionoftheInternationalDiabetesFederation(IDF).RequeststoreproduceortranslateIDFpublicationsshouldbeaddressedtoIDFCommunications,AvenueEmiledeMot19,B-1000Brussels,byfaxat+32-2-538-5114,orbye-mailatcommunications@idf.org©InternationalDiabetesFederation,2007ISBN2-930229-48-9.GuidelineforManaGeMentofPostMealGlucoseMethodologyThemethodologyusedinthedevelopmentofthisguidelineisnotdescribedindetailhere,asitbroadlyfollowstheprinciplesdescribedintheIDFGuideforGuidelines().Insummary:•Theprocessinvolvedabroadlybasedgroupofpeople,includingpeoplewithdiabetes,healthcareprofessionalsfromdiversedisciplinesandpeoplefromnon-governmentalorganizations.TheprojectwasoverseenbyaSteeringCommittee(seeSteeringCommittee)andinputwasprovidedbytheentireGuidelineDevelopmentGroup(seeMembersoftheGuidelineDevelopmentGroup).•TheGuidelineDevelopmentGroupincludedpeoplewithconsiderableexperienceinguidelinedevelop-mentandhealthcaredevelopmentanddeliveryandlivingwithdiabetes.•GeographicalrepresentationincludedallIDFregionsandcountriesindifferentstatesofeconomicdevelopment(seeMembersoftheGuidelineDevelopmentGroup).•Theevidenceusedindevelopingthisguidelineinclu-dedreportsfromkeymeta-analyses,evidence-basedreviews,clinicaltrials,cohortstudies,epidemiologi-calstudies,animalandbasicsciencestudies,positionstatementsandguidelines(Englishlanguageonly).AscientificwriterwithknowledgeofdiabetesobtainedrelevantreportsthroughacomputerizedsearchoftheliteratureusingPubMedandothersearchengines;scanningofincomingjournalsinthemedicallibraryandreviewofreferencesinpertinentreviewarticles,majortextbooksandsyllabifromnationalandinternationalmeetings,onthesubjectsofdiabetes,usingrelevanttitleandtextwords(egpostprandial,postmeal,hyper-glycaemia,mealtime,self-monitoring,oxidativestress,inflammation)assearchcriteria.Evidencerelatingtobothpostmealandpostchallengeplasmaglucosewasreviewedandcitedasappropriate.Areviewofrecentguidelines,positionstatementsandrecentarticlesnotidentifiedintheuniversalsearchwasalsoconductedtoobtainadditionalinformationthatwaspotentiallyapplicabletothequestions.Anelectronicdatabasewascreatedtoincludefullreferenceinformationforeachreport;abstractsformostofthereportswereincludedinthedatabase.MembersoftheSteeringCommitteewereaskedtoidentifyanyadditionalreportsorpublicationsrelevanttothequestions.Intotal,1,659reportswereidentified.•Keyreports,whethersupportiveornot,wereincludedandsummarizedbasedontheirrelevancetotheques-tionstobeaddressedbythisdocument.TheevidencewasgradedaccordingtocriteriapresentedinTable1.Theevidencecitedtosupporttherecommendationswasreviewedbytwoindependentexternalreview-erswhowerenotpartoftheGuidelineDevelopmentCommittee.CommentsfromtheexternalreviewerswerethenreviewedbytheSteeringCommittee.•Evidencestatementswerecompiledbaseduponreviewoftheselectedreports.ThesestatementsandsupportingevidenceweresenttoSteeringCommitteemembersfortheirreviewandcomment.•TheGuidelineDevelopmentCommitteemettodis-cusstheevidencestatementsandsupportingdataandtodeveloptherecommendations.Arecommendationwasmadeaccordingtothelevelofscientificsubstan-tiationbasedonevidenceratingswheneverpossible.However,whentherewasalackofsupportingstudies,theSteeringCommitteeformulatedaconsensusrec-ommendation.•Thedraftguidelinewassentoutforwiderexter-nalreviewtoIDFmemberassociations,globalandregionalIDFelectedrepresentatives,interestedpro-fessionals,industryandothersonIDFcontactlists,foratotalof322invitations.Thirty-eightcommentsfrom20externalreviewersfromfiveofthesevenIDFregions(Africa,SouthEastAsia,WesternPacific,NorthAmerica,Europe)werereceived.Thesecom-mentswerereviewedbytheSteeringCommitteeandconsideredindevelopingthefinaldocument.•ThefinalguidelineisbeingmadeavailableinpaperformandontheIDFwebsite.Theevidenceresourcesused(orlinkstothem)willalsobemadeavailable.•IDFwillconsidertheneedtoreviewandupdatethisguidelinewithinthreeyears.GuidelineforManaGeMentofPostMealGlucoseMembersoftheguidelinedevelopmentCommitteeSteeringCommittee•Anto