中国药剂学杂志

73Vol.7No320095ChineseJournalofPharmaceuticsMay2009p.19820081006(1965),,,,,,Tel.[phone](O),[e-mail](2009)030198071.1101712.110016O/Wnm2001(emulsions1Fig.1Sortsofemulsionsemulsion31991100µmO/WW/OmultipleemulsionsW/O/WO/W/OW/OO/W50µmsubmicroemulsions0.10.5µm10100nmO/W200871Table1Thesituationofseveralemulsions’nameintheliteraturesNameCnkiVipWanfangdataPatentLipidemulsions0121Fatemulsions19146237560Submicroemulsions25324110Lipidmicrospheres19823123011lipidemulsionorfatemulsionO/W2007LCTMCT10%20%30%10%200500nm100nm402080E120020.05%Aresta-sisTMrefreshendura1Washinton1997lipidemulsionsLE20050lipidmicrospheres,LM3201lipidnanospheres,LNLMLN2005submicronemulsions100600nmWashintonlipidemulsionorfatemulsionfatemulsion[3]lipidemulsionsWashinton50200nm100600nmlipidnanosphereslipidmicrospheresspheresLEO/W0.050.6µm0.2µm0.05µm0.050.6µmC14-24fatemulsioninjectionfatemulsionlipidemulsions2027lipidemulsion3HMLEMM46KupfferLERESLEa.b.c.d.LM3203LELELELELELEPEGLELELE[1],,,.[J].,2004,3(5):12951298.[2],.[J].2005,29(8):359363.[3].:[J]..,1997,24(5):305308.[4]C14246[S].[5].:[J]..,1986,(5):268269.[6],,.[J].,2008,39(1):5660.Definitiondiscriminationofanewdrugcarrier-lipidemulsionsXUEBai-zhong1,TONGMeng1,RENLi1,SHANXue-zhi1,CAIPei-lie1,CHENDa-wei2(1.LiaoningNuokangBiotechnologyPharmaceuticalCo.,Ltd,Shenyang,1101712.ShenyangPharmaceuticalUniversity,Shenyang110016,China)Abstract:Uptonow,therearenodefinitionsaboutlipidemulsionsandfatemulsionsintheclassicalpharmaceuticsbooks,obscuredefinitionshavebeenusedintheliteraturesandevenforthesameproduct,itis2047nominatedwithdifferentdosagenames.Inthispaper,anewdefiniationforlipidemulsionswasputforward,anditwassuggestedthatnutritionalfatemulsionscouldbenamedas“fatemulsions”andnamemedicatedfatemulsionsas“lipidemulsions”.Wehopethattheexpertsintheacademiacouldtakethissuggestionintoconsideration.Keywords:pharmaceutics;lipidemulsion;fatemulsion;lipidmicrosphere;lipidnanosphere()