中药抗淋球菌的实验研究

Aug.2009,Volume6,No.8(SerialNo.57)JournalofUS-ChinaMedicalScience,ISSN1548-6648,USA32∗11122121.3440002.33000615mg24G1G2G3211352121TheexperimentalresearchoftraditionalChinesemedicinetoAnti-NeisseriagonorrhoeaeDENGShen-yun,HUYing-hui,CHENGHui-long,HUANGWen-chang,MAXi-mei,ZHANGZhi-hong,SHILin-boAbstract:ObjectiveTofindtheeffectiveChinesemedicinetoresisttheepidemicNeisseriagonorrhoeae,whichisresistanttopenicillin.MethodsThecommonlyusedChinesemedicinewasselectedtocarryonvitrobacteriostasisexperimentwithquantitativemedicinemethodofplatepaperdiscbyadoptingdouble-blindexperiment.ResultsTheresultsshowedtherewerekindsofhighconcentration(15mg)ChineseHerbsontheNeisseriagonorrhoeaewithvaryingdegreesofinhibition,21,13,5traditionalChinesemedicinehadbetterinhibitoryactionontheG1,G2,G3epidemicstrainsofNeisseriagonorrhoeae,ofwhich,the21traditionalChinesemedicineswasthemostantibacterialmedicineforthegonococcus.Conclusion21etckindsoftraditionalChinesemedicineshavethevaryingdegreeinhibitoryactionontheepidemicNeisseriagonorrhoeaestrainsresistanttodrug,andthereisthebroadapplicationprospectinthedevelopmentoftraditionalChinesemedicineanti-epidemicgonococcus.Keywords:traditionalChinesemedicine;epidemicNeisseriagonorrhoeae;experimentalinvitroantibacterial∗2003030808【】19681942STD58[1]STD50%[2]1993200071.60%[3][4]1.1.11.1.1692050g250ml0.50.5250ml0.550ml1ml1g1.1.25.5mm51015ul51015ul1.1.33G1.21.2.1GC20001015pH7.415121℃1580℃12:11.2.21-20.03mol/LPH7.25×106cfu/ml51015ul35ml36℃24361.2.315ul3GC35.5310mm1015mm15mm2.596932434.78%116930304050709101112131415171821313334373940434446580102060816192022232425262728293032353638414245474849505152535455565759606162636465666768693.MIC21145G1G2G3G1219443331138213[1].[J].200023154-56.[2].1993-2000[J].2003242119-122.[3].19[J].200310448-49.[4].[M].1991.JaneChen