双氢青蒿素抗肺癌及逆转耐药作用研究

第四军医大学博士学位论文双氢青蒿素抗肺癌及逆转耐药作用研究姓名：陈卫强申请学位级别：博士专业：内科学（呼吸系病）指导教师：戚好文20040501双氢青蒿素抗肺癌及逆转耐药作用研究作者：陈卫强学位授予单位：第四军医大学参考文献(109条)1.参考文献2.王三根.梁颖中药青蒿的生态生理及其综合利用[期刊论文]-中国野生植物资源2003(4)3.刘旭近年来青蒿素类药物研究的进展[期刊论文]-广西医学2003(10)4.王红.叶和春.刘本叶.李振秋.李国凤青蒿素生物合成分子调控研究进展[期刊论文]-生物工程学报2003(6)5.杨耀芳青蒿素及其衍生物的药理作用和临床应用[期刊论文]-中国临床药学杂志2003(4)6.TaylorWR.RigalJ.OlliaroPLDrugresistantfalciparummalariaandtheuseofartesunate-basedcombinations:focusonclinicaltrialssponsoredbyTDR12003(3-4)7.Eckstein-LudwigU.WebbRJ.VanGoethemID.EastJM,LeeAG,KimuraM,O'NeillPM,BrayPG,WardSA,KrishnaSArtemisininstargettheSERCAofPlasmodiumfalciparum2003(6951)8.翟自立.王振果自由基调节青蒿素类药物的抗血吸虫作用[期刊论文]-中国热带医学2003(3)9.严笠.甘绍伯.齐志群.李爽双氢青蒿素治疗急性弓形虫感染小鼠疗效的进一步观察[期刊论文]-寄生虫与医学昆虫学报2000(2)10.杨宝峰.李玉荣.徐长庆.罗大力.李宝馨.王惠珍.周晋青蒿素抗心律失常的作用机理[期刊论文]-中国药理学与毒理学杂志1999(3)11.高玉祥青蒿琥酯免疫作用的研究[期刊论文]-蚌埠医学院学报1998(5)12.董妍君.李卫东.屠呦呦.张慧娜.邹万忠.杨岚.林志彬双氢青蒿素对BXSB小鼠狼疮肾炎的作用及机制研究[期刊论文]-中国药理学通报2003(10)13.娄小娥.周慧君.杨波青蒿琥酯钠对大鼠抗孕作用的研究[期刊论文]-中国现代应用药学2002(3)14.McLeanWG.WardSAInvitroneurotoxicityofartemisininderivatives1998(z3)15.SmithSL.MaggsJL.EdwardsG.WardSA,ParkBK,McLeanWGTheroleofironinneurotoxicity:astudyofnovelantimalarialdrugs1998(4-5)16.KamchonwongpaisanS.McKeeverP.HosslerP.ZifferH,MeshnickSRArtemisininneurotoxicity:neuropathologyinratsandmechanisticstudiesinvitro1997(01)17.翟海峰青蒿素类抗疟药神经毒性研究概述1999(04)18.赵艳红.王京燕青蒿素类药物神经毒性及其作用机制[期刊论文]-中国寄生虫学与寄生虫病杂志2002(1)19.冯文宇.王琳.孙琴.田吉青蒿油乳抗人肝癌细胞增殖生长抑制实验[期刊论文]-泸州医学院学报2003(5)20.林芳.钱之玉.薛红卫.丁健.林莉萍青蒿素和青蒿琥酯对人乳腺癌MCF-7细胞的体外抑制作用比较研究[期刊论文]-中草药2003(4)21.杨小平.张星青蒿酯钠诱导人肿瘤细胞凋亡及其分子机制的探讨[期刊论文]-中草药2002(9)22.杨小平.潘启超.梁永钜.张以琳青蒿酯钠的抗肿瘤作用[期刊论文]-癌症1997(3)23.张居馨.王士贤青蒿琥酯对人宫颈癌HeLa细胞的乏氧杀伤和辐射增敏作用初探2001(12)24.肖柳英.林培英.张丹.陈绮文.李浩亮.冯昭明.张宏青蒿琥酯对小鼠肝癌及S180实体瘤的抑制作用[期刊论文]-实用癌症杂志2001(3)25.ChenHH.ZhouHJ.WuGD.LouXEInhibitoryeffectsofartesunateonangiogenesisandonexpressionsofvascularendothelialgrowthfactorandVEGFreceptorKDR/flk-12004(01)26.WoerdenbagHJ.MoskalTA.PrasN.MalingreTM,el-FeralyFS,KampingaHH,KoningsAWCytotoxicityofartemisinin-relatedendoperoxidestoEhrlichascitestumorcells1993(06)27.BeekmanAC.WoerdenbagHJ.VanUdenW.PrasN,KoningsAW,WikstromHVStabilityofartemisinininaqueousenvironments:impactonitscytotoxicactiontoEhrlichascitestumourcells1997(12)28.BeekmanAC.WierengaPK.WoerdenbagHJ.VanUdenW,PrasN,KoningsAW,el-FeralyFS,GalalAM,WikstromHVArtemisinin-derivedsesquiterpenelactonesaspotentialantitumourcompounds:cytotoxicactionagainstbonemarrowandtumourcells1998(07)29.JeyadevanJP.BrayPG.ChadwickJ.MercerAE,ByrneA,WardSA,ParkBK,WilliamsDP,CosstickR,DaviesJ,HigsonAP,IrvingE,PosnerGH,O'NeillPMAntimalarialandantitumorevaluationofnovelC-10non-acetaldimersof10beta-(2-hydroxyethyl)deoxoartemisinin2004(05)30.McCartyMFTurningan'Achilles'Heel'intoanasset-activationofHIF-lalphaduringangiostatictherapywillincreasetumorsensitivitytoiron-catalyzedoxidativedamage2003(04)31.EfferthT.OlbrichA.BauerRmRNAexpressionprofilesfortheresponseofhumantumorcelllinestotheantimalarialdrugsartesunate,arteether,andartemether2002(04)32.GalalAM.RossSA.ElSohlyMA.ElSohlyHN,El-FeralyFS,AhmedMS,McPhailATDeoxyartemisininderivativesfromphotooxygenationofanhydrodeoxydihydroartemisininandtheircytotoxicevaluation2002(02)33.SinghNP.LaiHSelectivetoxicityofdihydroartemisininandholotransferrintowardhumanbreastcancercells2001(01)34.SadavaD.PhillipsT.LinC.KaneSETransferrinovercomesdrugresistancetoartemisinininhumansmall-celllungcarcinomacells2002(02)35.PayneAGExploitingintracellularironandiron-richcompoundstoeffecttumorcelllysis2003(02)36.PosnerGH.PaikIH.SurS.McRinerAJ,BorstnikK,XieS,ShapiroTAOrallyactive,antimalarial,anticancer,artemisinin-derivedtrioxanedimerswithhighstabilityandefficacy2003(06)37.PosnerGH.NorthropJ.PaikIH.BorstnikK,DolanP,KenslerTW,XieS,ShapiroTANewchemicalandbiologicalaspectsofartemisinin-derivedtrioxanedimers2002(01)38.WuJM.ShanF.WuGS.LiY,DingJ,XiaoD,HanJX,AtassiG,LeonceS,CaignardDH,RenardPSynthesisandcytotoxicityofartemisininderivativescontainingcyanoarylmethylgroup2001(05)39.VennerstromJL.DongY.AndersenSL.AgerALJr,FuH,MillerRE,WescheDL,KyleDE,GerenaL,WaltersSM,WoodJK,EdwardsG,HolmeAD,McLeanWG,MilhousWKSynthesisandantimalarialactivityofsixteendispiro-1,2,4,5-tetraoxanes:alkyl-substituted7,8,15,16-tetraoxadispiro[5.2.5.2]hexadecanes2000(14)40.袁淑兰.王修杰.魏于全丹参酮抗肿瘤作用及其机理的研究[期刊论文]-癌症2003(12)41.刘宝瑞.钱晓萍.邹征云四种中药制剂对人大肠癌Moser细胞增殖与凋亡的影响[期刊论文]-南京大学学报(自然科学版)2002(5)42.杨玉琪.李玛琳人参皂甙的抗肿瘤作用及其机制[期刊论文]-药学进展2003(5)43.李旭芬.张苏展.郑树苦参碱对K562及其多药耐药细胞K562/Vin的细胞生物学影响[期刊论文]-中国病理生理杂志2002(10)44.李军涛.蒋忠军.陈守义.阮承迈维甲酸和人参皂甙对肝癌细胞端粒酶活性的影响[期刊论文]-热带医学杂志2002(1)45.袁淑兰.王修杰.魏于全丹参酮抗肿瘤作用及其机理的研究[期刊论文]-癌症2003(12)46.Moye-RowleyWSTranscriptionalcontrolofmultidrugresistanceintheyeastSaccharomyces200347.KolaczkowskiM.KolaczowskaA.LuczynskiJ.WitekS,GoffeauAInvivocharacterizationofthedrugresistanceprofileofthemajorABCtransportersandothercomponentsoftheyeastpleiotropicdrugresistancenetwork1998(03)48.HigashiK.UedaY.IkedaR.KodamaY,GuoJ,MatsunariI,OguchiM,TonamiH,KatsudaS,YamamotoIP-glycoproteinexpressionisassociatedwithFDGuptakeandcelldifferentiationinpatientswithuntreatedlungcancer2004(01)49.GoldmanBMultidrugresistance:cannewdrugshel