国际药品制造商协会联合会(IFPMA)全球医药及健康产业

InternationalFederationofPharmaceuticalManufacturers&Associations96.83%9388+453.3100684313.72351/24%10%13.71799.725%36+67+8723%7.711.6THEPHARMACEUTICALINDUSTRYANDGLOBALHEALTHFACTSANDFIGURES2014Thiscompendiumoffactsandfiguresrelatingtothepharmaceuticalindustryandglobalhealthaimstoprovideasnapshotoftheworkthisindustryundertakestoday.Thispublicationexaminesthemostrecentdataonpharmaceuticalinnovationandglobalhealth,accesstomedicinesandhealthcaresystems,aswellastheeconomicfootprintofthepharmaceuticalindustry.Theinformationpresentedhereconfirmstherankingoftheresearch-basedpharmaceuticalindustryasoneofthemostinnovativesectorsintheworld,whichoverthepastcenturyhasplayedauniqueroleindevelopingnewandimprovedmedicinesandvaccinestopreventandtreatdiseases.Thisisauniqueindustry.IFPMAmembersemployovertwomillionofpeoplewhoareproudtoparticipateinthiscrucialendeavor.Theirworksavesmillionsoflivesandhelpsthosesufferingfromdiseasetorecoverandleadmoreproductiveones.IFPMAbringsthispublicationtounderlinetheongoingcommitmentoftheresearch-basedpharmaceuticalindustrytoimprovingthequalityoflifeforalloftheworld’speople.Wehopethatsharingsomeofthemostrecentandrelevantfactsandfiguresrelatingtoourworkcanaddvalueforevidence-basedpolicymakingintheglobalhealtharena.©RocheTableofcontentsINDEXOFFIGURES,CHARTSANDTABLES...............................................................................4KEYFACTS....................................................................................................................................51.PHARMACEUTICALINNOVATIONANDPUBLICHEALTH....................................................7AlookintothepharmaceuticalindustryR&Dpipeline.................................................................8PharmaceuticalindustryR&DInvestments...................................................................................12PharmaceuticalR&Danditsimpactonglobalhealth..................................................................15IncrementalInnovation.....................................................................................................................18R&Dfordiseasesthatdisproportionatelyaffectthedevelopingworld......................................202.ACCESSTOMEDICINESANDHEALTHCARESYSTEMS.....................................................23Distributionofwealthandhealthoutcomes.................................................................................23Healthcarespendingandworkforce................................................................................................25Barrierstoaccesstomedicinesandhealthcare............................................................................28Theroleofpharmaceuticalproductsinhealthcare......................................................................30Pharmaceuticalindustry’scontributiontoimprovingglobalhealth.........................................33Healthcareachievementsandchallenges......................................................................................363.ECONOMICFOOTPRINTOFTHEPHARMACEUTICALINDUSTRY.....................................39PharmaceuticalR&Dandproduction..............................................................................................40Pharmaceuticalindustryemployment...........................................................................................43Transferoftechnology.......................................................................................................................44Tradeinpharmaceuticals.................................................................................................................46Genericversusbrandedpharmaceuticalproducts.......................................................................50Conclusion............................................................................................................................................51ANNEXES.....................................................................................................................................52Annex1–Lifeexpectancyandcauseofdeath...............................................................................53Annex2–Healthfinancing...............................................................................................................63Annex3–Pharmaceuticalsales.......................................................................................................68Annex4–Pharmaceuticalvalueadded...........................................................................................76Annex5–Pharmaceuticalemployment.........................................................................................77ABOUTTHEIFPMA....................................................................................................................80Indexoffigures,chartsandtablesFIGURESFigure1.............................................8TheresearchanddevelopmentprocessFigure2...........................................11PharmaceuticalR&DnetworksFigure3.............