年产1亿支盐酸普鲁卡因注射液工艺设计

一次，他在核实数据时，认为部分数据需要重新测量，但项目部的车都被派出去了。belimitedtonomorethan2daysofwork,materialdepositedinspecialinsulatedcontainers,materialhandlingtogentlyandmakeuseofthermalinsulationmaterialinwindproof,waterproof,moisture-proofmeasure.6.2thermaldesignoptimizationforhigh-temperaturespecialthermalinsulationforpipingsupportandhangerdesign,reducedheatdissipationofthehangers,ensurethatthewalldoesnotoverheat.Small-diameterpiping,thermalinstrumentlayoutandpositioningofsupportandhangerdesigntakefullyintoaccounttheexpansionspaceandinsulationthickness.Large-diameterpipesafterheatpreservationplasteringconstructionofvalves,turbine,checkingsmoothsurface,hightemperaturepowderpaintfullydryafter.Protectivecoveringsforelectricequipmentinsulationboardsdesignedwithpressureplate,whenorderingaccordingtotheinstallationdiagram,modelspecificationspublishingorder,ensurewheninstallingcornersneat,uniformappearance,reducetheamountofon-sitemachining.Beforevalves,flangeinsulationshellconstruction,besuretomakeaunifiedmodel,allvalves,flanges,insulationcoverunified,tidyandbeautiful.Whenfourpartssuchaspipes,boilerinsulation,mustdofirstarticleinspection,proofofdesignandconstructionmethods,technologycanmeetthetechnologicalrequirements,beforeextensiveconstruction.Boilersteelbeams,dooropeningboxesdesignedwithinsulationgaskets,flangecannotbeoblique,evenfastened.Backintotheslopeofthetubingduringinstallationpayattentiontothepiping,oilstationisalowpoint.Refuelingmustbecontrolledwhencastingmaterialparts,selectlowthermalconductivitymaterialsasfaraspossible,ensurethatthesepartsdonotoverheat.6.3qualitydefectsofinsulationtechnologymanagementoptimizationofconstructionprocessanddevelopareasonableduration,regionaltransferofstrictly课程设计说明书目录第一章前言1.1前言··········································2第二章设计概述2.1车间设计概述·········································32.2设计目的·······································32.3设计依据·······································4第三章设计资料3.1生产规模及包装形式····························43.2生产制度······································4第四章工艺设计计算及生产过程4.1物料衡算······································54.2生产工序······································54.3盐酸普鲁卡因注射剂处方举例···················104.4生产工艺流程图·······························11第五章生产设备选型5.1主要设备选型·································125.2安瓿澄明度光电自动检查仪说明·················17第六章车间设计说明第七章附图一次，他在核实数据时，认为部分数据需要重新测量，但项目部的车都被派出去了。belimitedtonomorethan2daysofwork,materialdepositedinspecialinsulatedcontainers,materialhandlingtogentlyandmakeuseofthermalinsulationmaterialinwindproof,waterproof,moisture-proofmeasure.6.2thermaldesignoptimizationforhigh-temperaturespecialthermalinsulationforpipingsupportandhangerdesign,reducedheatdissipationofthehangers,ensurethatthewalldoesnotoverheat.Small-diameterpiping,thermalinstrumentlayoutandpositioningofsupportandhangerdesigntakefullyintoaccounttheexpansionspaceandinsulationthickness.Large-diameterpipesafterheatpreservationplasteringconstructionofvalves,turbine,checkingsmoothsurface,hightemperaturepowderpaintfullydryafter.Protectivecoveringsforelectricequipmentinsulationboardsdesignedwithpressureplate,whenorderingaccordingtotheinstallationdiagram,modelspecificationspublishingorder,ensurewheninstallingcornersneat,uniformappearance,reducetheamountofon-sitemachining.Beforevalves,flangeinsulationshellconstruction,besuretomakeaunifiedmodel,allvalves,flanges,insulationcoverunified,tidyandbeautiful.Whenfourpartssuchaspipes,boilerinsulation,mustdofirstarticleinspection,proofofdesignandconstructionmethods,technologycanmeetthetechnologicalrequirements,beforeextensiveconstruction.Boilersteelbeams,dooropeningboxesdesignedwithinsulationgaskets,flangecannotbeoblique,evenfastened.Backintotheslopeofthetubingduringinstallationpayattentiontothepiping,oilstationisalowpoint.Refuelingmustbecontrolledwhencastingmaterialparts,selectlowthermalconductivitymaterialsasfaraspossible,ensurethatthesepartsdonotoverheat.6.3qualitydefectsofinsulationtechnologymanagementoptimizationofconstructionprocessanddevelopareasonableduration,regionaltransferofstrictly-2-第一章前言1.1盐酸普鲁卡因注射液介绍1.1.1盐酸普鲁卡因注射液的药理毒理本品为酯类局部麻药，能暂时阻断神经纤维的传导而具有麻醉作用，本品对皮肤、粘膜穿透力弱，不适于表面麻醉。本品弥散性和通透性差，其盐酸盐的结合形式在组织中被解离后释放出游离碱而发挥局部麻醉作用。本品对中枢神经系统常量抑制，过量兴奋。首先引起镇静、头昏，痛阈提高，继而引起眩晕、定向障碍、共济失调,中枢抑制继续加深,出现知觉迟钝、意识模糊，进而进入昏迷状态。剂量继续加大，可出现肌肉震颤、烦燥不安和惊厥等中枢兴奋的中毒症状。本品小剂量有兴奋交感神经的作用，使心率加快、血压上升，剂量加大，由于心肌抑制，外周血管扩张、神经节轻度阻断而血压下降，心率增快。本品抑制突触前膜乙酰胆碱释放，产生一定的神经肌肉阻断，可增强非去极化肌松药的作用，并直接抑制平滑肌，可解除平滑肌痉挛。1.1.2体内过程本品进入体内吸收迅速，很快分布,维持药效约30～60分钟。大部分与血浆蛋白结合，并蓄积在骨骼肌、红细胞等组织内，当血浆浓度降低时再分布到全身。在血循环中大部分迅速被血浆中假性胆碱酯酶水解，生成对氨基苯甲酸和二乙氨基乙醇，前者80%以原形和结合型，后者仅有30%经肾脏排出，其余经肝酯酶水解，进一步降解后随尿排出。本品易通过血脑屏障和胎盘。1.1.3适应症短效局部麻醉药。用于浸润麻醉、阻滞麻醉、腰椎麻醉、硬膜外麻醉和封闭疗法等。亦可用于静脉复合麻醉。1.1.4不良反应本品可有高敏反应和过敏反应，个别病人可出现高铁血红蛋白症；剂量过大，吸收速度过快或误入血管可致中毒反应。年产1亿支盐酸普鲁卡因注射剂工艺设计一次，他在核实数据时，认为部分数据需要重新测量，但项目部的车都被派出去了。belimitedtonomorethan2daysofwork,materialdepositedinspecialinsulatedcontainers,materialhandlingtogentlyandmakeuseofthermalinsulationmaterialinwindproof,waterproof,moisture-proofmeasure.6.2thermaldesignoptimizationforhigh-temperaturespecialthermalinsulationforpipingsupportandhangerdes