常见中药补剂的毒性与安全问题分析

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286200812()JOURNALOFHUIZHOUUNIVERSITYVol1281No16Dec12008:2008-10-28:(1968-),,,,,(,516015):,:;;;:R87:A:1671-5934(2008)06-0063-051[1]59,105,,,:2060[1]1999,,,,,,,2211,(),:,,,,,,,,,,19905316,300,215;2870,210,2000534,72,10[2],,,,,,()()()200828::(1):,,,;,,,,[3-4];,,[5];,[6];,[7](2):2,,,[8](3):,,,[9](4):,20:,,;,;,,,;,;,[10-11](5):[12](6):[13](7):,;,[14](8):,,(9):,,(10):[15](11)::,,,,,;,;,,,;,,,:(1):,,,,,,,(2):,[15](3):(4):,,,,,,,(5):,,3,2,,,,;,;,;,,;[17](6):1,:(1):,(2):,,30(3):,,,,[18](4):,,466:,:(1):,;1;()(2):,(3):;,,,[19](4):,[20](5):(6):(7):,,;[21](8):;[22](9):,212,60%[2]3-9g,60g;,9-15g,30-60g,1000g,,,,3-9g,20g,213(1)-(ACTH)()(),,(2)(),(),(3),;,;,;,(4),,,,;,,,;,(5)(Warfarin),,,,,214,,:,,,,,,:,:,;,,;,,,::,,:56()200828,,;,,,,:,,,,,215,,,,,216,,,,,,,,,;,,3311,:,,,,,,,,,,,[2],:,;,;,,312,60%,,:,,;,;,,313,,,,,,,,,,,,,,,,,,:[1].[J].,2000,23(4):490-492.[2],.[M].:,2002:1-6.[3],.36[J].,1999,21(5):223.[4],.34[J].,1999,10(4):331.666:[5]DUKUSMN.Ginsengandmastalgia[J].BrMedJ1978;1(6127):1621.[6]PALOP-LARREAV,GONZALEZ-PERALESJL,CATALAN-LIVER,etal.Metorrhagiaandginseng[J].AnnPharmacother2000,34(11):1347.[7]DEGAH,LAPORTEJL,FRANCEC,etal.GinsengasacauseforStevens-Johnsonsyndrome?[J].Lancet,1999.347(9011):1344.[8]PAULPui-HayBut,KANWing-Kay.AdversereactionstoChinesemedicineinHongKong[J].AbstractsofChineseMedi2cines,1995,6(1):104.[9].1[J].,1993,(4):246[10],.[J].,1998,(5):29[11]ADRIANEFugh-Berman.Herb-druginteractions[J].Lancet,2000,355:134[12].3[J].,1987,(4):45.[13].1[J].,1992,(1):55.[14],.:[M].:,1998:1585.[15].[J].,1992,(7):29.[16]HECKAM,DEWITTBA,LUKESAL.Potentialinteractionsbetweenalternativetherapyofwarfarin[J].AmJHealthSystPharm,2000,57(13):1221.[17].2.,1998,7(4):287.[18],,.1[J].,1998,13(5):200.[19],.:[M].:,1998.1677.[20].[J].,1982,(4):32.[21].[J].,1990,25(10):475.[22].[M].:,1998:125.:AResearchintotheSafetyandToxicityofCommonChineseHerbalTonicZHANGZong2guo(DepartmentofPhysicalEducation,HuizhouUniversity,Huizhou516015,GuangChina)Abstract:UsingthemethodsofdocumentarysummarytoanalyzethereasonsandmeasuresofpreventingbadreactionaftertakingChi2neseherbal,thepaperprovidestheoreticalandpracticalreferencetofurtheruse.Keywords:Chineseherbaltonic;badreaction;toxicity;dialectics76

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