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分类号TP393密级公开UDC硕士学位论文流通链中药品安全管理系统设计及关键技术研究学位申请人：陈锦鹏学科专业：计算机应用技术指导教师：陈晓辉副教授二○一三年五月ADissertationSubmittedinPartialFulfillmentoftheRequirementsfortheDegreeofMasterofScienceinEngineeringDrugSafetyManagementSystemDesignandKeyTechnologyResearchontheCirculationChainGraduateStudent:ChenJinpengMajor:ComputerAppliedTechnologySupervisor:AssociateProf.ChenXiaohuiChinaThreeGorgesUniversityYichang,443002,P.R.ChinaMay,2013三峡大学硕士学位论文I三峡大学学位论文原创性声明本人郑重声明：所呈交的学位论文，是本人在导师的指导下，独立进行研究工作所取得的成果，除文中已经注明引用的内容外，本论文不含任何其他个人或集体已经发表或撰写过的作品成果。对本文的研究做出重要贡献的个人和集体均已在文中以明确方式标明，本人完全意识到本声明的法律后果由本人承担。学位论文作者签名：日期：三峡大学硕士学位论文II内容摘要RFID技术是近年来应用逐渐成熟的识别技术，由于RFID标签具有非接触识别、存储容量大、传输速度快、身份标识的唯一性与无法复制性、可并发识别等特点，可以将RFID标签附着在药品上，依托RFID技术和数据库技术，在标签和数据库中实时记录药品的相关信息，实现药品流通的全程监管和信息查询，满足政府日益增长的严格监管，以便在药品出现问题时及时进行追溯，更有效的进行药品的安全管理。同时由于RFID具有远距离无接触识别，成本低廉，抗干扰能力强的优势，在定位中也具有独特的优势。本课题首先对流通链中药品安全管理系统中进行了设计，并针对流通链药品安全管理中存在的薄弱点，重点对流通链的药品运输环节和终端信息查询展开研究，课题分析了药品运输环节中环境监控的现状和不足，并重点对药品在运输途中因意外导致的运输厢体局部存储环境发生变化且难以有效监控的问题，提出了一种解决方案。该方案提出了一种基于三维空间的插值算法来获取厢体运输空间中温度的立体分布，并提出了一种RFID定位算法实现对厢体环境中药品的定位，在实际环境中证明了该定位算法的有效性。通过将某空间超标温度的坐标与对应位置的药品坐标进行关联，利用标签的存储功能，实现将运输空间中超标的温度写入对应位置的药品标签中，从而实现对药品在运输途中存储环境的全程监控。在流通链中药品安全管理系统的实现环节，重点从流通链终端销售环节着手，分析了药品防伪的现状，并从消费者的实际需求出发，分析了现有智能终端与RFID读写器结合的可能性，并最终实现串口和USB接口的智能终端与现有RFID读写器的结合，消费者通过智能终端采集RFID标签的数据，并通过无线网络访问远程数据库（验证性数据库），可以有效地获取药品相关信息，鉴别药品的真伪，提高用药的安全性。关键词：RFID药品流通链药品运输空间插值定位三峡大学硕士学位论文IIIAbstractRFIDtechnologyisappliedmaturelygradually,duetothefeaturesofnon-contactrecognition,largestoragecapacityandfasttransmissionspeed,theuniquenessofidentificationandcannotreproduceeasily,concurrentlyidentifycharacteristicsandsoon.RFIDtagscanbeattachedtodrugproduct.BasedontheRFIDtechnologyanddatabasetechnology,druginformationcanberecordedinlabelsanddatabase.So,itconsonantlymonitorthecirculationofmedicinesandanti-counterfeitquery,whichcansatisfytheincreasingofgovernmentregulation.Whenthedrugsthreatenthelife,itcanbeinatimelymannertocarryontheback,moreeffectivefordrugsafetymanagement.AsRFIDhasthetheadvantagesofnon-contactrecognitionatadistance,stronganti-interferenceability,andthecostislow,itisalsohastheuniqueadvantageinthelocalization.Thispaperfirstdesignthedrugsafetymanagementsystemonthecirculationchain,andaimtotheshortageofenvironmentmonitoringindrugtransportationanditsactualneeds,especiallyforthelocalenvironmenthaschangedunexpectedlyintransit,anditishardtomonitorthechangedenvironment,andthispaperproposesanewsolution.Thissolutionproposesaninterpolationalgorithminthe3-Dspacetocapturethetemperaturedistributioninthespace.Further,thispaperproposesaRFIDlocalizationalgorithmtocalculatethepositionofdrugs,andthesimulationandactualexperimenthasprovedtheefficiencyoflocalizationalgorithm.Thenthecoordinateofspacetemperaturecanbeassociatedwiththecorrespondinglocationofdrug,andtheexcessivetemperaturecanbewrittenintheRFIDtags,sothestorageenvironmentintransitcanbemonitoredefficiently.Ontheotherhand,thispaperaimstothesalessectioninthecirculationchain,andanalysesthecounterfeitingsituationofdrugs.Fromthepracticaldemandsofconsumer,thispaperanalyzestheuniversalintelligentterminalandcostfactors,anewideathatcombinedintelligentterminalandtheexistingRFIDreaderispresented,anditrealizedthecombinationofserialportandUSBintelligentterminalwithRFIDReader.DuetotheRFIDtagdataandtheintelligentterminalofthewirelessnetwork,theterminalcustomerscanaccessaremotedatabase(anexperimentaldababase)effectivelyandidentifytheauthenticityofadrug,anditcanguaranteethepatient'smedicationsafetyeffectively.Keywords:RFIDDrugcirculationchainDrugtransportSpatialinterpolationLocalization三峡大学硕士学位论文IV目录引言··················································································11绪论··················································································21.1课题研究背景及意义·····································································21.2国内外研究进展·············································································31.3研究内容及思路·············································································41.4论文的组织结构·············································································72流通链中药品安全管理系统设计··············································92.1无线射频RFID技术概述································································92.2用户需求分析···············································································162.3功能模块设计···············································································172.4流程设计·······················································································192.5架构设计·······················································································202.6核心子系统设计···········································································212.7本章小结·······················································································233运输厢体中的温度监控························································243.1温度特征分析···············································································243.2传统温度监控方法···························································