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B43MIMS.COM-MIMS••••••••5•GFRGuidetoDrugsinPatientswithRenalImpairment243CAPD801/2BritishNationalFormulary,Number47,March200420-50mL/min150-300umol/L10-20mL/min300-700umol/L10mL/min700umol/L•L/24hrs=mL/minx1.44•mL/min=L/24hrsx0.69AAbacavir-Abciximab-AcamprosateAcarbose-25mL/-ACEInhibitorsCaptopril12.5mg2Cilazapril500ug1Enalapril2.5mg1Imidapril2.5mg130mL/minMoexipril3.75mg1Perindopril2mg12mg1Quinapril2.5mg1Ramipril1.25mg1Trandolapril500ug1Acebutololβ2-AceclofenacAcemetacinAcetazolamide-Aciclovir--Acipimox-CrCl30mL/minAAcitretinAcrivastine-CH_Appendix7_KidneyDisease.p652008-11-3,17:2343B44MIMS.COM-MIMS-10mg/1Adefovirdipivoxil-10mg/721--AdrenergicNeuroneBlockersAlcuronium-Alendronicacid-AlfentanilAlfuzosin-Alimemazine-Allopurinol-100-200mg/-100mg/1Almotriptan-12.5mg/AlprazolamAlteplase-Aluminiumsalts-Amantadine-CrCl60mL/min-AmfebutamoneBuproprionAmikacinAmilorideAminoglycosidesAmobarbital-Amoxicillin-Amphotericin-Ampicillin-Amprenavir--AmsacrineAnalgesicsAnastrozole20mL/-Anticoagulants,Oral-AmisulpirideClozapineOlanzapineQuetiapineRisperidoneSulpiride-ChloralhydrateApomorphine-2mg+-Artemether+LumefantrinepotassiumAspirin-Atenololβ2-AuranofinSodiumaurothiomalateAzapropazone-300mg2CrCl60mL/min-Azathioprine-AzithromycinAztreonam-BBaclofen-Bambuterol-BemiparinBendroflumethiazideBenorilateBenperidolcBenzodiazepinesBenzylpenicillin-6g/β2--Beta-blockers-BisoprololNebivololCeliprololAcebutololAtenololNadololPindololSotalolBezafibrate-CrCl15mL/min-Bleomycin-BumetanideBuprenorphineBuspirone--CH_Appendix7_KidneyDisease.p652008-11-3,17:2344B45MIMS.COM-MIMSCCandesartanCapecitabine-CrCl30-50mL/3/4CrCl30mL/Capreomycin-CaptoprilCarbamazepineCarbenoxolone-Carboplatin--CefadroxilCefalexinCefiximeCefotaximeCefoxitin-CefpiromeCefpodoximeCefprozilCefradine-CeftazidimeCeftriaxone-2gCefuroxime-CelecoxibCeliprololβ2-CertoparinCetirizineChloralhydrateChlorambucilChloramphenicol-cChlordiazepoxideChloroquine--ChlorpromazineChlorpropamideChlortalidoneChlortetracyclineCiclosporinCyclosporin-CidofovirCilazaprilCilostazolCrCl25mL/Cimetidine200mg/121Ciprofibrate-100mg-CiprofloxacinCisplatinCitalopram-CitratesCladribineClarithromycinCrCl30mL/ClavulanicacidClobazamClodronatesodiumSodiumclodronateClomethiazoleClopamidecClorazepateCloxacillin-Clozapine-12.5mg/--Co-amoxiclavCodeineColchicine--Colistinx-CrCl15-30mL/Co-trimoxazoleCrCl15mL/CyclopenthiazideCyclophosphamideCycloserine--DDacarbazine--DalteparinDaunorubicin-DebrisoquineCH_Appendix7_KidneyDisease.p652008-11-3,17:2345B46MIMS.COM-MIMSDemeclocyclineDesflurane-DesmopressinDexketoprofenDextromethorphanDextropropoxypheneDiamorphineDiazepamDiazoxide-DiclofenacDidanosineDiflunisalDigitoxin-100ugDigoxinDihydrocodeinecDiltiazemDimercaprolDiphenoxylateDipipanone-Disodiumetidronate-DisodiumpamidronateDisopyramide/DoxycyclineEEfavirenzEletriptan-20mg40mg/CrCl30mL/EmtricitabineEnalaprilEnflurane-EnoxaparinEnoximoneEphedrine-EprosartanEptifibatideCrCl30mL/Ergometrine-Ergotamine-Erythromycin-Esmololβ2-Ethambutol-CrCl30mL/EtidronatedisodiumEtodolacEtoricoxibFFamciclovir-Famotidine--FenbufenFenofibrate--FenoprofenFentanylFlecainide100mg/Flucloxacillin-Fluconazole50mL/FlucytosineFludarabine30-70mL/CrCl30mL/FlunitrazepamFluoxetine--FlupentixolFluphenazineFlurazepamFlurbiprofenFluvastatin-FluvoxamineFondaparinuxCrCl30mL/FoscarnetFosinoprilFosphenytoin10-25%Frusemide-FurosemideGGabapentinGalantamine-Gallamine-GanciclovirCH_Appendix7_KidneyDisease.p652008-11-3,17:2346B47MIMS.COM-MIMSGemcitabine-Gemfibrozil--GentamicinGestrinone-Glibenclamide-Gliclazide--Glimepiride-Glipizide--GliquidoneGuanethidineHHaloperidolHeparin--Hetastarch-HydralazineCrCl30mL/HydrochlorothiazideHydroflumethiazideHydromorphone-Hydroxychloroquine-HydroxyzineHypnoticsIIbandronicacid5mg/dL442umol/LIbuprofenIdarubicin--IfosfamideImidapril+5mL/Imipenem+CilastatinIndapamideIndometacinInosinepranobexInsulin-α-Interferonalfa--β-Interferonbeta-Iohexol-Iopanoicacid-IrinotecanIsoniazid-200mg/AIsotretinoinItraconazoleCrCl30mL/KKetoprofenKetorolacLLamivudineLamotrigine-Lercanidipine-LevetiracetamLevocabastine-30-49mL/Levocetirizine5mg/110-30mL/5mg/3110mL/LevofloxacinLevomepromazineLisinoprilLithiumsalts+Lopinavir+Ritonavir-LoprazolamLorazepamLormetazepamLosartan-25mg//LymecyclineMMagnesiumsalts-MefenamicacidMeloxicamMelphalan-MemantineCrCl40-60mL/10mg/-MeprobamateCH_Appendix7_KidneyDisease.p652008-11-3,17:2347B48MIMS.COM-MIMSMeptazinolMercaptopurine-Meropenem/Mesalazine--Metformin1.4-1.5mg/dLMethadoneMethenamine-MethocarbamolMethotrexate--MethotrimeprazineMethyldopa-Methysergide-MetoclopramideMetolazoneMetoprololβ2-MidazolamMilrinoneMinocyclineMivacurium-Modafinil-MoexiprilMorphineMoxonidine-200ug400ug-NNabumetoneNadololβ2-NalbuphineNalidixicacid-NaproxenNaratriptan-2.5mg/-Nebivololβ2-NelfinavirNeomycinNeostigmine-NetilmicinNicardipine-NicoumaloneNitrazepamNitrofurantoinNitroprussideNizatidine--1/4NorfloxacinCrCl30mL/NSAIDs--OOfloxacin--Olanzapine5mg/OlmesartanCrCl20-60mL/20mg/CrCl20mL/Olsalazine--/-OpioidAnalgesicsOseltamiv