高雄医学大学药学院

高雄醫學大學藥學院藥學系暨藥學研究所蔡義弘教授藥劑學及生物藥劑學研究室●●●●任教科目（A）大學部：藥劑學生物藥劑學臨床藥物動力學（B）藥學研究所：藥劑學特論高級藥劑學特論藥物動力學特論●●●●最高學歷日本京都藥科大學藥學博士●●●●經歷高雄醫學院藥學系副授教(1979/8-1982/7)高雄醫學院藥學系講師(1973/8-1979/7)高雄醫學院藥學系助教(1969/3-1973/7)高雄醫學院藥學系系主任高雄醫學院藥學研究所所長高雄醫學院附設中和紀念醫院藥劑科主任高雄醫學院訓導長日本京都藥科大學研究員●●●●最新動態藥學院院長(2005/4-迄今)●●●●[e-mail]●●●●聯絡電話：[phone]ext.2261傳真：[phone]●●●●研究室網頁：●●●●研究專長藥物輸送系統之研究●●●●著作論文代表（2001年〜迄今）1.Jia-YouFang,Song-YihYu,Pao-ChuWu,Yaw-Bin.HuangandYi-HungTsai＊＊＊＊.2001.Invitroskinpermeationofestradiolfromvariousproniosomeformulations.Int.J.Pharm.,215,91-99.2.Jia-YouFang,Ren-JiunnWang,Yaw-Bin.,Huang,Pao-ChuWuandYi-HungTsai＊＊＊＊,2001.Influenceofelectricalandchemicalfactorsontransdermaliontophoreticdeliveryofdiclofenacsalts.Biol.Pharm.Bull.24(4),390-394.3.Yaw-Bin.,Huang,Min-JunTsai,Pao-ChuWu,Chia-LangTsai,J.I.ChangandYi-HungTsai＊＊＊＊,2001.Transdermalesterdioldeliveryfromvolatilevehiclesthroughexcisedrabbitskin:effectoflipophilicenhancers.N.TaipeiJ.Med.3,107-114.4.Pao-ChuWu,Jui-ShengChang,Yaw-Bin.Huang,Chee-YinChai,Yi-HungTsai＊＊＊＊,2001.Evaluationofpercutaneousabsorptionandskinirritationofketoprofenthroughratskin:invitroandinvivostudy.Int.J.Pharm.222,225-235.5.Hung-HongLin,H.M.Yu,Tsai,Yi-Hung;Li-RenHsu,2001.ThepreparationofEnoxacin-loadedliposomesanditsinvitroevaluationinpig'seye.ChiaNanAnnualBulletin,ChiaNanAnnualBulletin,27,109-116.6.Jia-YouFang,Tsong-LongHwang,Yaw-BinHuang,andYi-HungTsai＊＊＊＊,2002.TransdermalionophoresisofsodiumnonivamideacetateV.combinedeffectofphysicalenhancementmethod.Int.J.Pharm.235,95-105.7.Min-JunTsai,Yaw-Bin.Huang,Pao-ChuWu,Hui-ChuanChen,andYi-HungTsai＊＊＊＊,2002,MonitoringAminoAcidNeurotransmittersinPlasmaProfilesandPredictingEarlyProgressionofIschemicStroke.Chin.Pharm.J.54,215-224.8.Jia-YouFang,Yann-LiiLeu,Ying-YueWang,andYi-HungTsai*,2002,InvitrotopicalapplicationandinvivopharmacodynamicevaluationofnonivamidehydrogelsusingWistarratasananimalmodel.Eur.J.Pharm.Sci.15,417-243.9.Yaw-Bin.Huang,Yi-HungTsai,Jui-ShengChang,Jian-ChenLiu,Min-JunTsai,andPao-ChuWu*,2002,EffectofAntioxidantsandAnti-irritantsontheStability,SkinIrritationandPenetrationCapacityofCaptoprilGel.Int.J.Pharm.241,345-351.10.Pao-ChuWu,Min-JunTsai,Yaw-Bin.Huang,Jui-ShengChang,andYi-HungTsai*,2002,Invitroandinvivoevaluationofpotassiumchloridesustainedreleaseformulationpreparedwithsaturatedpolyglycolyedglyceridesmatrices.Int.J.Pharm.243(1-2)119-124.11.Ching-HsinChang,Shan-YangLin*,andYi-HungTsai.2002.Thermal-inducedChangesintheSecondaryConformationofSuperoxideDismutaseContainingDifferentMetalIons.JournalofBiomolecularStructureDynamics;20(1):81-86.12.Fwu-LongMi,Yi-MeiLin,Yu-BeyWu,Shin-ShingShyu*,Yi-HungTsai,2002.Chitin/PLGAblendmicrospheresasabiodegradabledrug-deliverysystem:phase-separation,degradationandreleasebehavior.Biomaterials.23:3257-3267.13.Fwu-LongMi,Yu-BeyWu,Shin-ShingShyu,Jen-YuSchoung,Yaw-BinHuang,Yi-HungTsai,Jong-YunHao,2002.Controlofwoundinfectionsusingabilayerchitosanwounddressingwithsustainableantibioticdelivery.JournalofBiomedicalMaterialsResearch.59(3):438-449.14.Pao-ChuWu,Yaw-BinHuang,Jui-ShengChang,Ming-JunTsai,andYi-HungTsai*,2003,DesignandevaluationofsustainedreleasemicrospheresofpotassiumchloridepreparedbyEudragit®.Eur.J.Pharm.Sci.19(2-3)115-122.15.Pao-ChuWu,Yaw-BinHuang,Jui-IChang,Ming-JunTsai,andYi-HungTsai*,2003,PreparationandevaluationofsustainedreleasemicrospheresofpotassiumchloridepreparedwithEthylcelluloseInt.J.Pharm.260,115-121.16.Yaw-BinHuang,Jia-YouFang,Pao-ChuWu,Tsung-HsienChen,Ming-JunTsai,andYi-HungTsai*,2003,Noninvasiveglucosemonitoringbybackdiffusionviaskin:chemicalandphysicalandphysicalenhamcements.Biol.Pharm.Bull.26(7),983-987.17.Jui-IChang,Yaw-BinHuang,Pao-ChuWu,Chao-ChengChen,Shun-ChenHuang,andYi-HungTsai*,2003,CharacterizationofhumancervicalprecanceroustissuethroughtheFouriertransforminfraredmicroscopywithmappingmethod.GynecologicOncology91(2003)577–583.18.Fwu-LongMi,Shin-ShingShyu*,Yi-MeiLin,Yu-BeyWu,Chih-KangPeng,Yi-HungTsai.2003.Chitin/PLGAblendmicrospheresasabiodegradabledrugdeliverysystem:anewdeliverysystemforprotein.Biomaterials.24,5023-5036.19.Pao-ChuWu,Yi-HungTsai,Chung-ChengLiao,Jui-ShengChang,Yaw-BinHuang*,2004.Thecharacterizationandbiodistributionofcefoxitin-loadedliposomes.Int.J.Pharm.271,31-39.20.Yaw-BinHuang,Jui-ShengChang,Jian-ChenLiu,Min-JunTsai,Yi-HungTsai,andPao-ChuWu*.2004.Theinfluenceofanti-irritantsoncaptoprilhydrophilicgel.DrugDev.Ind.Pharm.30,163-169.21.Jia-YouFang*,Yann-LiiLeu,Chia-ChunChang,Chia-HsuanLin,Yi-HungTsai,2004.Lipidnano/submicronemulaionsasvehiclesfortopicalflurbiprofendelivery.DrugDeliv.11,97-105.22.Yaw-BinHuang,Jui-ShengChang,Pao-ChuWu,Yi-HungTsai*,2004.DeterminationofXanthonololbyHigh-performanceLiquidChromatographyforPharmacokineticStudiesinRats.J.FoodDrugAnal.12(2)97-101.23.Yaw-BinHuang,Yi-HungTsai,Wan-ChiechYang,Jui-ShengChang,Pao-ChuWu*.2004.InfluenceofformulationvariablesandmanufacturingprocessonpropranololextendedreleaseprofilefromHPMCmatricestablets.J.Appl.Polym.Sci.93,1886-1890.24.Chih-HuiYang,Pao-ChuWu,Yaw-BinHuang,Yi-HungTsai*.2004.Anewapproach