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:(1980),,,3,E2mail:lab2004@1631com,3,(,116012):,:;;;,,,,1992116DendriticPolymer,,,,,,,(1)1Figure1Schematicrepresentationofpropertiesofdendrimersandtheirpotentialasfunctionalmacromolecules1,,,,61120056,,,,,Maciejewski[1]1982,,Meijer[2,3](PPI),,,,Daniel[4]DAB(NH2(CH2)4NH2)H2PO4-,,H2PO4-,E1P2205mv250mv280mv,,H2PO4-VÊgtle[5]2CH2Cl2,52(N,N2)212(dansyl)90%,,80%64,,Forster,P2Figure2Chemicalstructureofthedendrimerswithnaphthalenecontaininggroups,,,,LBCardullo[6]C60,2L2BC60Crooks[7,8],2(PAMAM)2,pHpH:pH;pH,,2PAMAM,(MUA),(SPR)01340103,89%2[9],,,,71132,,DNA(3)3Figure3DendriticnanodevicesfortherapeuticapplicationRoyZanini[1013]L2,,,816L2A,Frchet[14,15],(PEG),(indomethacin)11%(wt),Malik[16]PAMAM,2,315Kojima[17]PEG,,,PAMAM,HIV1HIV2CMVHSV,[18]Jevprasesphant[19]PAMAM(G2,G3,G4)2000PEG,Caco22,PAMAM,PEGDNADNADNA200DNADNA,,111In153GdPAMAM,[20],,,90HaenslerSzoka[21]PAMAM510GPAMAMDNA,DNADuncan[22]PAMAM,,,,,:PAMAM,,PAMAM,,20%25%(BNCT),10BPAMAM(G2,G4),,VÊgtlePAMAM,,,[23]81120056(MRI),,CT2,(hFR),2,[24]Baker[25]PAMAMMRI,(FITC),,Kobayashi[26]PAMAMDABMRI,DABPAMAM,,3,VÊgtle[27],,,481632,,2,,Shibaev[28](4),(105),23n23,280nm2,,,(),Brewis[29](POM),234(105)(106)Figure4Chemicalstructureofthefirstgenerationdendrimerswithcinnamoyl2containing105andazobenzenecontaining106groups9113FeOsRuZn,,,,Yoon[30]PAMAM(64),,(5)5PAMAMFigure5Ferrocene2basedpolymerspossessingPAMAMcores,LED(1,422)(PPV),LED4,(,),,,,,:(1);(2);(3);(4)Brunner[31],Cu(),,Niu[32]PAMAMPd,NaBH4,,,N2[33]3PAMAM,TiCl4,3Ti,3,2Ford[34]3662232Reetz[35],,,,Soai[36]636,,ee86%N2,ee94%021200566Figure6Chiraldendriticcatalystsandligandswithhydrocarbon[poly(phenylethyne)]backbones:,,,,(DEMNs),DEMNs:(1);(2)4nm,,Crooks[37]G42OH(Pd40)(40Pd4PAMAM)G32OH(Pd10)Suzuki,G32OH(Pd10)G42OH(Pd40),,,,5,,(EKC),Gray[38]PAMAM,,,,,,pH,Mezzenga[39],,Allen[40],,[41]PAMAM,TNT,,,:[1]MaciejewskiM.JMacromolSciChem,1982,A117:6891[2]JansenJFGA,deBrabander2vandenBergEMM,MeijerEW.Science,1994,266:12261[3]BosmanAW,JansenJFGA,JansenRAJ,etal.PolymMaterSciEng,1995,73:3401[4]DanielMC,RuizJ,AstrucD.JAmChemSoc,2003,125:11501[5]BalzaniV,VÊgtleF.CRChimie,2003,6:8671[6]CardulloF,DiederichF,Echegoyen,etal.Langmuir,1998,14:19551[7]LiuY,BergbreiterDE,CrooksRM,etal.AngewChemIntEdEngl,1997,36:21141[8]LiuY,BergbreiterDE,CrooksRM,etal.JAmChemSoc,1997,119:87201[9]HongMY,YoonHC,KimHS.Langmuir,2003,19(2):41611213[10]RoyR,ZaniniK,MeunierSJ,etal.JChemSoc,ChemCommun,1993,24:18691[11]ZaniniD,RoyR.JAmChemSoc,1997,119:20881[12]ZaniniD,RoyR.JOrgChem,1998,63:34861[13]RoyR,ParkWKC,WuQ,etal.TetrahedronLett,1995,36:43771[14]LiuM,KonoK,FrchetJMJ.JPolymSci,PartA:PolymChem,1999,37:34921[15]LiuM,KonoK,FrchetJMJ.JControlledRelease,2000,65:1211[16]MalikN,EvagorouEG,DuncanR.AnticancerDrugs,1999,10(8):7671[17]KojimaC,KonoK,MaruyamaK,etal.Bioconjug,Chem,2000,11(6):9101[18]MattthewsBR,HolanG.WorldPatent,95P34595119951[19]JevprasesphantR,PennyJ,JalalR,etal.IntJPharm,2003,252:2631[20],.,2003,30(6):3481[21]HaenslerJ,SzokaFC.BioconjugChem,1993,4(5):3721[22]DennigJ,DuncanE.RevMolBiotechnol,2002,90:3391[23]VÊgtleF,FischerM.AngewChemIntEd,1999,38:8841[24]KondaSD,ArefM,WangS,etal.MagnResonMaterPhysBiolMed,2001,12:1041[25]BakerJRJr,QuintanaA,PiehlerL,etal.BiomedMicrodevices,2001,3:611[26]KobayashiH,HenryL,MartinW,etal.BioconjugateChem,2003,14:3881[27]VÊgtleF,GestermannS,HesseR.ProgPolymSci,2000,25:9871[28]ShibaevV,BobrovskyA,BoikoN.ProgPolymSci,2003,28:7291[29]BrewisM,ClaksonGJ,etal.AngewChemIntEdEngl,1998,37:10921[30]YoonHC,HongMY,KimHS.AnalChem,2000,72(18):44201[31]BrunnerH.JOrganometChem,1995,500:391[32]NiuY,YeungLK,CrooksRM.JAmChemSoc,2001,123:68401[33],,,.,2001,22:7091[34]LeeJ,FordWT,MooreJA,etal.Macromolecules,1994,27:46321[35]ReetzMT,GiebelD.AngewChemIntEd,2000,39:2498[36]SoaiK,SatoI.CRChimie,2003,6:10971[37]NiuYH,RichardM,Crooks.CRChimie,2003,6:10491[38]GrayAL,HsuJT.JChromatogrA,1998,824:1191[39]MezzengaR,MansonJAE.JMatSci,2001,36:48831[40]AllenL,PolverariM.NordPulpPaperRes,2000,15(5):4071[41],..:,2002,400.DevelopmentofDendrimersPracticalUsingResearchLIUHai2feng,WANGYu2rong3,RENYan(DepartmentofPolymerScienceandMaterials,DalianUniversityofTechnology,Dalian116012,China)Abstract:Dendrimersaremono2distributedandnano2scalemacromolecules.Owingtotheuniquefeatures,dendrimershavepotentialapplicationsinmanyareas.Inthispaper,theresearchandapplicationofdendrimersinthefieldsofsupramolecularchemistry,biomedicinalchemistry,photochemistry,electrochemistry,catalystandsoon,werereviewed.Keywords:Dendrimers;Supramolecular;Photoswitchabledendrimers;Nano2catalyst22120056