:,;Tel:15809436543;E-mail:lyz6543@163.com2009李玉珍,赵艳侠,杜素芬(, 730900): 了解白银市第一人民医院住院病人医嘱不合理用药的情况,提高临床合理用药水平。2009年临床药师每月抽查审核出院病历,根据病人的临床诊断,结合实验室检查及特殊检查报告单等,判定用药的合理性,对不合理用药病历作出统计分析。2009年共计抽查审核病历5785份,不合理用药127份,占住院病历的2.2%。本院用药基本合理,但还存在缺陷,需进一步规范。: 住院病人;合理用药;临床药师:R969.3 :A :1002-7777(2011)07-0740-03AnalysisonIrrationalDrugUseinOurInpatienton2009LiYuzhen,ZhaoYanxiaandDuSufen(FirstPeopleHospitalofBaiyin,Baiyin730900)ABSTRACT: ObjectiveTounderstandirrationaldruguseinFirstPeopleHospitalofBaiyin,toimproveclinicalrationaldruguse.MethodsTheclinicalpharmacistsin2009,monthlyreviewedhospitalrecordsselectedrandom.Basedonthepatient'sclinicaldiagnosis,withlaboratorytestsandspecialexaminationreport,etc.,theydeterminedthereasonablenessofmedication,andmedicalhistoryofirrationaldrugusewasstatisticallyanalyzed.ResultsTotalofselectiveexaminationrecordsin2009were5785copies,irrationaldruguserecordsaccountedforhospitalized127of2.2%.ConclusionDruguseisbasicallyreasonableinourhospital,buttherestillexistsomedefectstofurtherstandardize.KEYWORDS: patientshospitalized;rationaldruguse;clinicalpharmacist1 20091~12,,、、,,、,。:,[1],、《》[2]、《》[3]、《》[4]。2 5785,127,2.2%。2118,1。1 52 50 13 11 8β- 7 5 4 4 4 2 11 1 :127,,1。74020112573 3.1 ,、,。,,ADR(、、),、、。,,,。,,G+/。,,,COPD、、。、,、,,。,,。,,。,;;、,。,、,、、,,,,,,,;、、,β-,,、,。3.2 、、,,50S,,,[5]。3.3 ,。、、、、,、、,,、、、。,。。;;;、、、;;;;;、;、;;;,;;;、,;;;;;;,、。3.4 [6-7]。、,,。;,,。3.5 ,。。85,0.75g,。AST45u·L-1,CRE120.6umol·L-1,ALT26u·L-1;5,AST65u·L-1,CRE197.1umol·L-1,ALT125u·L-1,γ-GGT93u·L-1。,74120112571/2~2/3,。13,12kg,1g,,,。,,,。,,、、、0.5g,0.2g,。,,。、。,,,。,80mg,。40mg,,40mg,10。,,,。3.6 ,。、、、。3.7 。1,,41。,4~5,,。《》,72h。3.8 、β-,。,、,,;、,[7-8]。,pH7、,,。,[9],,,β,,。,。0.5~2,,;,3,(1500mL),48~72h。。3.9 。,、(R)、、/、(S),。3.10 、、,、。,,、,。:[1],,,..[M].:,2006:12-13.[2],,.[M].16.:,2007.[3].[Z].[2004]285,2004.[4].[Z].[2009]38,2009.[5],,,.[M].:,2000:51-53.[6].β-[J].,2002,11(23):2363-2364.[7],.β-[J].,2003,26(11):721-722.[8],,.β-[J].,2001,(1):43-44.[9].[J].,2005,3(3):178-179.7422011257