11268名健康体检人群甲状腺结节发生的流行状况调查分析-徐厚兰

201412312912DISEASESUＲVEILLANCEDecember312014Vol.29No.12·987·．jbjc．orgDOI10.3784/j．issn.[e-mail]2013－12－111126811211。20125201351126820、、、。Btlogistic。37.19%。BMI、、、P＜0.05。logistic、、、、、、。。、、、、、。Ｒ743A1003－9961201412－0987－05Surveyofprevalenceofthyroidnodulein11268peoplereceivinghealthexaminationXUHou-lan1WEIJing1LANMan2LIUMin-jie1JIANGYu1．1．AffiliatedHospitalofHangzhouNormalUniversityHangzhou310015ZhejiangChina2．ZhejiangHospital[e-mail]derstandtheprevalenceofthyroidnoduleinhealthypopulationandriskfactorsrelatedtothyroidnoduleprevalence．MethodsAtotalof11268peoplereceivinghealthexaminationmChengbeidistrictofHangzhoufromMay2012toMay2013wereincludedinthissurvey．Aquestionnairesurveywasconductedamongthesepeopletocollecttheinformationabouttheiroccupationeducationlevelhouseholdincomelifestyleandmentalstress．AccordingtotheresultsofthyroidtypeBultrasonicdetectiontheprevalenceofthyroidnodulewascalculated．Thedifferencesinhealthexaminationresultsbetweenthyroidnodulegroupandnon-thyroidnodulegroupwerecomparedwithttest．Logisticregressionanalysiswasconductedtoidentifytheriskfactorsrelatedtotheprevalenceofthyroidnodule．ＲesultsTheprevalenceofthyroidnoduleinthispopulationwas37.19%theprevalencewashigherinfemalesthaninmales．Thedifferencewasstatisticallysignificant．Theprevalenceofthyroidnodulewashigherinpeoplewithhigheducationlevelandhighmentalstress．Comparedwithnon-thyroidnodulegrouptheBMIbloodpressurebloodsugarleveltotalcholesterollevelandtriglyceridelevelweresignificantlyhigherinthyroidnodulegroupthedifferencewasstatisticalsignificant．Logisticregressionanalysisindicatedthatfemaleageobesityhypertensionhyperlipidemiadiabetesandsmokingmightberelatedfactorstothyroidnodule．ConclusionTheprevalenceofthyroidnoduleinhealthypeopleishigh．Theprevalenceissignificantlyhigherinfemalesthaninmales．Ageobesityhypertensionhyperlipidemiadiabetessmokingmaybetherelatedfactorstothyroidnodules．Peoplewithhigheducationlevelwereathigherrisk．KeywordsThyroidnodulePrevalenceＲiskfactor。5%～15%1。19733.6/1020028.7/1021978200033198120011.934。·988·201412312912DISEASESUＲVEILLANCEDecember312014Vol.29No.12．jbjc．orgDOI10.3784/j．issn.1003－9961.2014.12.017。2012520135。11.12012520135725。、、、ALT/AST＞2.5Ccr＜25ml/min、。1.21.2.1。①、、、、、②、。、/、/4、、、、、、、4WHO116WHO16。1.2.2、、、4。BMIBMI=kg/m2。WHOBMIBMI＜18.518.5～24.925～29.930。1.2.3、、4。12～14h。19WHOWHO/IDF5。、6。、、3。1.2.47.5MHz。20097。、、、。1.2.5EpiData3.0。1.2.6SPSS13.0。《2012》《2013》。。t。logisticOＲ95%CI。P＜0.05。22.111268625955.6%500944.4%208238.56±7.32。50.0%79.1%。1。2.2、112685074.50%。5009591.18%62594487.16%201412312912DISEASESUＲVEILLANCEDecember312014Vol.29No.12·989·．jbjc．orgDOI10.3784/j．issn.1003－9961.2014.12.0171Table1Basicinformationof11268peoplereceivinghealthexaminationn=11268n%n%500944．49388．3625955．6281925．0563450．020～128311．4187716．730～174515．440～244721．7272324．250～262223．2/836374．260～207918．4/1821．670～8210929．9235620．9347230．9891279．1779669．1＜3000512645．5246521．93000～512845．5880378．1＞500010149．0458337.19%。。10.76%89.24%、、10.28%、28.32%61.40%。170033.94%288346.06%χ2=344.52P=0.00P＜0.05。χ2=789.18P=0.00χ2=46.14P=0.00。、2。2.3、、、、3。t、、、P＜0.05P＞0.05。2.4。χ2、、BMI、、、、、、、logistic。、、、、、、、。“”、“”P＞0.054。3、、、、2、Table2Sexandagespecificprevalenceofthyroidnoduleinpeoplereceivinghealthexaminationn=11268%%%20～534397．4174911813．54128315710．6830～6999512．54104629425．81174538924．1440～105631030．21139160644．55244791635．7950～126349344．91135971150．612622120441．9460～101647447．53106366458．762079113849．8170～44128961．7765149064．87109277960．515009170030．556259288341．2811268458337．193Table3Comparisonofhealthexaminationresultsbetweenthyroidnodulegroupandnon-thyroidnodulegroupx±snBMImmHgmmHgmmol/Lmmol/Lmmol/Lmmol/Lμmol/L458325．11±2．01134．00±19．3380．00±17．255．92±1．365．17±0．911．67±1．213．26±1．01356．23±67．50668523．02±2．22125．00±21．5675．00±15．465．58±1．134．02±1．211．49±1．323．12±0．98354．86±69．38t2．303．254．022．034．452．871．281．62P0．020．030．010．040．010．020．310．841mmHg=0.133kPa。·990·201412312912DISEASESUＲVEILLANCEDecember312014Vol.29No.12．jbjc．orgDOI10.3784/j．issn.1003－9961.2014.12.0174logisticTable4MultivariateregressionanalysisresultsonriskfactorstothyroidnodulePOＲ95%CI1．020．032．781．59～9．94＜3030～0．100．781．100．55～2．1640～0．490．021．921．11～7．4550～1．010．011．861．12～9．48≥601．420．011．891．43～12．69BMI0．160．0951．540．88～3．190．680．041．450．89～4．851．980．012．081．58～6．250．750．031．591．22～6．180．060．121．510．88～3．350．020．011．071．02～2．440．200．022．161．54～12．480．330．022．001．34～6．860．010．651．640．91～4．850．970．011．541．28～8．190．220．041．221．02～5．780．480．011．641．25～9．48－0．350．550．810．38～3．210．680．811．530．51～8．641．240．012．851．28～10．21＜30003000～50000．430．081．120．82～1．78＞50000．570．111．160．86～5．1267%8926.30%1036.56%1141.93%。37.19%4.50%4.2%12。P＜0.05、、、13－15、、9－1116－17161718。。logistic、、、、、、。5%～15%。CDIColorDopplorImage。。CDI3～66～12。、、“”。、。1HegedüsL．ClinicalpracticethethyroidnoduleJ．NEnglJMed2004351171764－1771．201412312912DISEASESUＲVEILLANCEDecember312014Vol.29No.12·991