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2003Vo1.15No.1NATURALPRODUCTRESEARCHANDDEVELOPMENT:2002204223:20022052213(Correspondingauthor)(29872025)3(610065),;;(Tannicacid),,,,,,,1,,,,(Gallotannin)65156715%,68187114%,33193815%[1],75%90%(Caesalpiniaspiosa,tara),,90,,200km2,,[1]Reategui,EtOH2EtOAc(31),[2]3,6h,95%[3],,,,10,25%30%,,,,2,1,,,;;;1Fig.1ChemicalStructureofTannicAcid211,78,,,[4],pH,FeCl3212[57]80,Haslam2,,2,,(astringency),,213,pH(pH315),,,(O22)(OH),[8]214,,,3311(StreptococcusmutantsClarke),,,0125g/L100%,,,[910],(max=263nm,=8350),,[11],,50gSiO245g10%,5g50%40,,,2[12],,,,,[11],,,,[13]312,,,,[14],,,,,,(510)(510)(15)[15],,[16],()27,8229,10227,8,9,102,SENCAR[1718]882003Vo1.15No.1Gali,[19](AIDS),AIDS[21]G.T.Tan155HIV2RT,4:A(ID5050ug/mL),MA(ID50150ug/mL),WA(150ID50200ug/mL)IA(ID50200ug/mL),4A,HIV2RTase(HIV)50%50ug/mLUchiumi,122O222132JuekatT2HIV313,,,,,90%6g/100L,5mg/100mL,,[21],SO2,,[12],,,,,BHT,[22],,[23]314[2425]70,Rogers(1941),,,,,Russell(1945),Hu(1939),Glenz(1993),,Desimone(1995),,,,,,,,,,,315,,-OH-COOH,,,,Auger,Ca2p,-OH-COO-Ca2+[26],,pH9.5,,[27],90%[12],Ca2+Mg2+,,,,,,,,,,COD,[28],3g/L10g/L10g/L,,900982003Vo1.15No.1:90%[29],()Fe3+,2,,,,A3,,4g/L,20,pH3.5,60,Fe3+,,,[30]4,,,,,1..,2000,20(2):71802ReateguiGR,NakasoneRH.ProductionofgallicacidfromtanninsextractedfromCaesalpiniaspinasaKuntze(tara).ChemicalAbstracts,1989,110(4):983,,..,1996,16(3):79864HemingwayR,LakesP.PlantPolyphenols.NewYork:PlenumPress,1992:4214365HaslamE.Tannins.Polyphenolsandmolecularcomplexion.,1992,12(1):1236ShiB,HeXQ,HaslamE.Gelatin2polyphenolinteraction.JAmLeatherChemAssoc,1994,89:961027SpencerC,CaiY,MartinR,etal.Polyphenolcomplexion2somethoughtandobservation.Phytochem,1998,27(8):239724098,,...2000,12(5):1611709KakiuchiN,HattoriM,NishizawnM,etal.Studiesonden2talcariespreventionbytraditionalmedicines.InhibitoryeffectofvarioustanninsonglucansynthesisbyglucosyltransferasefromStreptococcusmutants.ChemPharmBull,1986,34(2):72072510IwamotoM,UchinoK,TouhairinT,etal.Thegrowthin2hibitionofStreptococcusmutantsby52nuchotidasein2hibitorsfromArecacatechuL.ChemPharmBull,1991,39(5):1323132411,..:,2000.19319712..,1995,(2):363713..:,1997.30330714HironoI.Naturallyoccurringcarcinogensofplantorigin.Elsevier,Amsterdam,1987:16116215AkiraN,TakashiS.Uptakeandrecoveryofgoldbyimmo2bilizedpersimmomtannin.JChemTechBiotechnol.1993,57:32132616HayatsuH,ArimotoS,NegishiT.Dietaryinhibitorsofmutagenesisandcarcinogenesis.MutantRes,1988,202:42944617MukhtarH,DasM,KhanWA,etal.Exceptionalactivityoftannicacidamongnaturallyoccurringplantphenolsinprotectingagainst7,122dimethylbenz(a)anthracene2,ben2zo(a)pyrene2,32methylcholanthrene2andN2methyl2N2ni2trosourea2inducedskintumorigenesisinmice.CancerRes.,1998,48:2361236518AtharM,KhanWA,MukhtarH.Effectofdietarytannicacidonepidermal,lungandforestomachpolycyclicaromatichydrocarbonmetabolismandtumorigenicityinSencarmice.CancerRes,1989,49:5784578819GaliHU,PerchelletEM,etal.Antitumor2promotingef2fectsofgallotanninsextractedfromvarioussourcesinmouseskininvivo.ChemicalAbstrats,1994,120(110):4620,,..,1998,32(2):111521,..,2000,20(1):1522,,..,2001,18(11):65365523ChungKT,LuZ,ChouMW.Mechanismofinhibitionoftannicacidandrelatedcompoundsonthegrowthofintesti2nalbacteria.FoodandChemicalToxicology,1998,36:1053106024..,2000,(2):697425DesimoneG,TomaselliM,etal.Tannageusingonlyveg2etabletanningmaterials.ChemicalAbstracts,1995,123092003Vo1.15No.1(20):21526,,..,1997,17(2):353727,,..,2000,21(4):26026228OmoikeAI,VanloonGW,Removalofphosphorusandor2ganicmatterbyalumduringwastewatertreatment.Wat.Res.,1999,33(17):3617362729RandallJM.Variationsineffectivenessofbarksasscav2engersforheavymetalions.ForProdJ,1977,27(11):515630,,.A3.,1996,18(3):5457CHEMICALPROPERTIESANDAPPLICATIONOFTANNICACIDMAZhi2hong,LUZhong2bing,SHIBi(TheKeyLaboratoryofLeatherChemistryandEngineeringofMinistryofEducation,SichuanUniversity,Chengdu610065,China)AbstractTannicacid,atypicalvegetabletannin,isaveryvaluablenaturalproductusedforwildfields.Thenat2uralresources,chemicalpropertiesoftannicacidweresummarizedinthispaper.Thedevelopmentandcurrentsituationofitsapplicationincosmethcs,medicine,food,leather2makingandotherindustrieswerealsodescribedindetail.KeywordsVegetabletannin;tannicacid;summarization(Ension),,3,::()()()3,;ISIS/BaseISIS/Draw;(WordExcel/);;256,;,;,:2003352003430,1020%:13816804759,zj-mkt@263.net:2000301915192003Vo1.15No.1: