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WilliamShakespearedescribedoldageas“secondchildishness”——sansteeth,sanseyes,sanstaste.Inthecaseoftastehemay,musicallyspeaking,havebeenevenmoreperceptivethanherealized.ApaperinNeurologybyGiovanniFrisoniandhiscolleaguesattheNationalCentreforResearchandCareofAlzheimer'sDiseaseinBrescia,Italy,showsthatoneformofseniledementiacanaffectmusicaldesiresinwaysthatsuggestaregression,ifnottoinfancy,thenatleasttoapatient'steens.Frontotemporaldementiaiscaused,asitsnamesuggests,bydamagetothefrontandsidesofthebrain.Theseregionsareconcernedwithspeech,andwithsuch“higher”functionsasabstractthinkingandjudgment.FrontotemporaldamagethereforeproducesdifferentsymptomsfromthelossofmemoryassociatedwithAlzheimer'sdisease,amorefamiliardementiathataffectsthehippocampusandamygdalainthemiddleofthebrain.FrontotemporaldementiaisalsorarerthanAlzheimer's.InthepastfiveyearsthecentreinBresciahastreatedsome1,500Alzheimer'spatients;ithasseenonly46withfrontotemporaldementia.TwoofthosepatientsinterestedDrFrisoni.Onewasa68-year-oldlawyer,theothera73-year-oldhousewife.Bothhadundamagedmemories,butdisplayedthesortsofdefectassociatedwithfrontotemporaldementia-adiagnosisthatwasconfirmedbybrainscanning.Abouttwoyearsafterhewasfirstdiagnosedthelawyer,onceaclassicalmusicloverwhoreferredtopopmusicas“merenoise”,startedlisteningtotheItalianpopband“883”。Ashiscommandoflanguageandhisemotionalattachmentstofriendsandfamilydeteriorated,hecontinuedtolistentothebandatfullvolumeformanyhoursaday.Thehousewifehadnotevenhadthelawyer'sloveofclassicalmusic,havingneverenjoyedmusicofanysortinthepast.Butaboutayearafterherdiagnosisshebecameveryinterestedinthesongsthather11-year-oldgranddaughterwaslisteningto.ThiskindofchangeinmusicaltastewasnotseeninanyoftheAlzheimer'spatients,andthusappearstobespecifictothosewithfrontotemporaldementia.Andotherstudieshaveremarkedonhowfrontotemporal-dementiapatientssometimesgainnewtalents.Fivesuffererswhodevelopedartisticabilitiesareknown.Andinanotherlapseofmusicaltaste,onewomanwiththediseasesuddenlystartedcomposingandsingingcountryandwesternsongs.DrFrisonispeculatesthattheillnessiscausingpeopletodevelopanewattitudetowardsnovelexperiences.Previousstudiesofnovelty-seekingbehaviorsuggestthatitismanagedbythebrain'srightfrontallobe.Apredominanceoftherightovertheleftfrontallobe,causedbydamagetothelatter,mightthusleadtoaquestfornewexperience.Alternatively,thedamagemayhaveaffectedsomespecificneuralcircuitthatisneededtoappreciatecertainkindsofmusic.Whetherthatisagainoralossisadifferentmatter.AsDrFrisoniputsitinhisarticle,degustibusnondisputandumest.Or,inplainerwords,thereisnoaccountingfortaste.11.ForShakespeare,oldageas“secondchildishness”fortheyhavethesameAfavorite.Bmemory.Cexperience.Dsense.12.WhichoneisnotasymptomofFrototemporaldementia?Athelossofmemory.Bthelossofjudgment.Cthelossofabstractthinking.Dthelossofspeech.13.Fromthetwopatientsmentionedinthepassage,itcanbeconcludedthatAtheircommandoflanguagehasdeteriorated.Btheiremotionalattachmentstofriendsandfamilyarebeinglost.CtheFrontotemporaldementiacanbringnewgifts.DFrontotemporaldementiacancausepatientstochangetheirmusicaltastes.14.The“novel”inthelastparagraphmeansAhistorical.Bspecial.Cstory-like.Dstrange.15.Fromthepassage,itcanbeinferredthatAthedamageoftheleftfrontallobemayaffectsomespecificneuralcircuit.Bthelawyerpatienthastheleftfrontallobedamaged.Cthedamageoftheleftfrontallobedecreasedtheappreciationcertainkindsofmusic.Deverypatienthasthesametaste.答案:DADDBAlHusseinis19.Heisstrugglingtostayseatedontopofahugetruckcrossingthedesert.Hehasbeenridinglikethatforhours,breathingdust,inanunbearableheat.Hehaslefthishome,histwinbrother,andtherestofhisfamilydownSouth.Beyondthedesertliesthesea,andmaybe,ifheisluckyaboattoEuropewherehehopestogetajob,tostartanewlife,andtosendmoneytohisvillage.AlHusseinishardlyaloneinhisperiloustrek.Some150millionmen,womenandevenchildren,aboutthreepercentoftheworld‘spopulation,areoutsidetheircountryoforigincomingasstrangerstothecountrywheretheyreside.Thereisnocontinent,noregionoftheworldwhichhasnomigrantswithinitsboundaries.Everycountryhasbecomeacountryoforigin,transitordestinationofmigrants.Manyareallthree.Morethanhalfofinternationalmigrantsliveindevelopingcountries.AccordingtotheInternationalOrganizationforMigration,thelargestnumbersofinternationalmigrantsarelocatedinAsia;EuropeandNorthAmericahaveaboutequalnumbersfollowedbyAfrica,LatinAmerica,andOceaniawithprogressivelyfewernumbers.TheInternationalLaborOrganization(ILO)estimatesthatupto80millionofthesearemigrantworkers.In1997,ILOestimatedthatthenumberofmigrantworkerswasasfollows:Africa,20Million;NorthAmerica,17million;CentralandSouthAmerica12million;Asia7million;theMiddleEast(Arabcountries),9million,andEurope30million.Migrationishardlyarecentorlocalizedphenomenon.Womenandmenhavebeenleavingtheirhomelandsinsearchofabetterjob.Peoplealsoleavetheirowncountriesbecauseofcivilconflictsandinsecurityorpersecution.However,inthisglobalizedworld,wearewitnessingunprecedentedlyhighlabormobilityandanincreasingpressureofmigration.GarethHowell,Inter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