(rheumatoidarthritis,RA),:50RA::A0.2130.8480;0.6470.8450.3810.5980.3070.8680.3480.545;A0.70,AA:ICC0.620.90;RA,RA,Apilotstudyofqualityoflifequetsionnaire(ChineseVersion)forpatientswithrheumatoidarthritisJiangLindi,JiJianlin,WangJiyao,etal.Departmentofrheumatology,ZhongShanhospital,ShanghaiMedicalUniversity,Shanghai200032AbstractObjectiveTodevelopaChinesequestionnaireforassessmentofthequalityoflife(QQL)inpatientswithrheumafoidarthritis(RA).MethodTheoriginalQOLQuestionnairewasestablishedbyfocusgroupdiscussion(FGD)withRApatients,aswellasreferringtosomeforeigninventories.ThecontentsofrevisedQOLquestionnaireconsistedoffoursub2scales:physical,emotionalöpsychological,socialfunctionsandself2recognizedhealthstatus.Eachitemofthisquestion2nairehadbeentestedandanalyzedtwiceby50RApatientseverytime.ResultAninter2itemcorrelationforeachofthefoursub2scaleswasrangefrom0.213to0.8480.Item2totalsub2scalecorrelationwas0.6470.845,0.3810.598,0.3070.858and0.3480.545respectively.Cronbach’salphaforthetotalsub2scalewasallabove0.70anditdecreasecomparedwiththeoverallsub2scalealpha,Wheneachitemomittedfromthesubscaleinturn.Test2retestreliabilityforthe29itemswas0.620.90.Factoranalysisshowedpreservationofthe42componentstructure.ConclusionItsuggestedthatQOLquestionnaireforRAisapractical,reliableandvalidinstrument.ItcanbeusedtoevaluatetheoutcomesoftheRApa2tients,especiallyfortheirphysical,emotionalöpsychological,socialfunctionsandself2recognizedhealthstatus.KeywordsArthritisRheumatoidQualityoflifeQuestionnaireX(RA),RA7080%,,,[1],,,RARA,,[2],,,(Focusgroupdis2cussion,FGD),FGD,:;2;,RA(1987)10;,RA,;;,[2],,Lee(1993)HAOMHAO[46]MHIQMACTAR[3],,9199981XINCLEN:200032©1995-2004TsinghuaTongfangOpticalDiscCo.,Ltd.Allrightsreserved.FGD,,,,,RA,8,5,;,;;,15,RA50,,,50RA,30,1.:Stata,(1):,,,(2)(inter2itemcorrelationmatrices):0.200.90,0.200.90,(3)2(item2subtotalcorrelation):0.2(4)A(cronbach’salpha):,A0.70;2.:,(intraclasscorrelationcoefficients,ICC)ICC0.6,;ICC0.75,3.:,,1,,,1,1()ö()45(2370)10ö4031620115.247(2869)14ö3641224104.9,60.0580.182,0.103,,(0.0930.129),,A,,,,,,,,5,,,,78771.:(1):ö,(2):0.2130.8480(3)2:0.6470.845;0.3810.598;0.3070.858,0.3480.545(4)A:A(2)0.70,AA2.:30RAICC0.60(01ChineseJournalofBehavioralMedicalScience,8(1),1999©1995-2004TsinghuaTongfangOpticalDiscCo.,Ltd.Allrightsreserved.3),3.:3469.2%,2APMSHA0.91889.75760.89200.797810.89930.75210.87380.775420.90540.75330.87820.759330.91030.73480.85510.741940.90520.74800.86460.739050.91330.71780.88400.734260.90620.74430.88010.762270.91670.70910.85960.732280.8801PMSH329(ICC)(%)31(P)2(M)3(S)4(H)P10.760.72---P20.720.61---P30.720.60---P40.650.58---P50.790.74---P60.680.74---P70.660.77---P80.620.77---m10.90-0.64--m20.64-0.86--m30.66-0.75--m40.63-0.88--m50.62-0.64--m60.84-0.58--m70.77-0.63--s10.80--0.72-s20.76--0.66-s30.64--0.81-s40.64--0.85-s50.62--0.54-s60.63--0.78-s70.68--0.82-h10.76---0.51h20.68---0.59h30.68---0.74h40.79---0.55h50.73---0.69h60.69---0.71h70.66---0.63:ICC:;plp8;mlm7;sls7;h1h7,,[2],RA,[7][8],,[7];RA,,LeeHAOMHAO,[34];MACTAR,[3]MHIO,,,,RA,,RA,RA,,;,RA,,RA,22RA,22(),,,(),,RA,,,,RA11199981©1995-2004TsinghuaTongfangOpticalDiscCo.,Ltd.Allrightsreserved.1.C.KentKwoh,RobertWS,LarryGA,etal.AmericanArthritisofRheumatologyADHOCCommitteeonclinicalguidelines.Guidelinesforthemanagementofrheumatoidarthritis.ArthritisRheum,1996,39(5):713722.2.,HendersonG,Higginbothamn.:.,1997.3.ChambersLW,MacdonaldLA,TUGWELLP,etal.TheMAC2TARpatientpreferencedisabilityquestionnaire2Anindividualfunctionalpriorityapproachforassessingimprovementinphysicaldisabilityinclinicaltrialinrheumatoidarthritis.JRheumatol.1987,14(3):446451.4.PincusT,SummeyJA,TugwellP,etal.Assessmentofpatientsatisfactioninactivitiesoflivingusingamodifiedstandfordhealthassessmentquestionnaire.ArthritisRheum,1990,33(4):591601.5.BellMJ,BombardierC,TugwellP,etal.Measurementoffunc2tionalstatus,qualityoflifeandutilityinrheumatoidarthritis.ArthritisRheum,1990,33(4):591601.6.MeenanRF,GertmanPM,MasonJH,etal.Measuringhealthstatusinarthritis:thearthritisimpactmeasurementscales.ArthritisRheum.1980,23(2):146152.7.BombardierC,WareJ,RussellIJ,etal.Auranofintherapyandqualityoflifeinpatientswithrheumatoidarthritis.AmJM.1986,81(4):565577.8.TugwellP,BomdardierC,BuchananWW,etal.Methotrexateinrheumatoidarthritis:impactonqualityoflifeassessedbytradi2tionalstandard2itemandindividualpatientpreferencehealtyatatusquestionnaires.ArchInternMed.1990,150:59629.MasonJH,AndersonJJ,MeenanRF,etal.Amodelofhealthstatusforrheumatoidarthritis.ArthritisRheum.1988,31(6):714720.(:,!)(:1998-06-19:)42,,1.CCMD2R;2.,,42(16,26),31.23,4.21,2.62,171.,(LES),2.Hamilton(HAMD),1.:12528,9,4,12.:7,8,7,3,2,11,33.:15;,11,6,10:HAMD247.42,16,,[1],:31,13[1],,,,,,1,40.5%,[2],2ö3,64.3%,,Hamilton,Bartels[3],,,,,,1...,1990:161163.2.():.,1984,11:191192.3.():.,1989,16:106.(:19980920::):27100021ChineseJournalofBehavioralMedicalScience,8(1),1999©1995-2004TsinghuaTongfangOpticalDiscCo.,Ltd.Allrightsreserved.