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(ICC)13ICC13(CEUS)CEUSSonoVue(CPS)13(100%)9(6912%),74(3018%)(n=1)(n=3),6(4612%)ICCCEUS,ICCContrastEnhancedUltrasoundFeaturesofIntrahepaticCholangiocarcinomaXuHuixiong,LiuGuangjian,LuMingde,etalDepartmentofMedicalUltrasonics,FirstAffiliatedHospital,SunYat2senUniversity,Guangzhou510080ChinaAbstract:ObjectiveToinvestigatethecontrastenhancedultrasound(CEUS)featuresofintrahepaticcholan2giocarcinoma(ICC)1MethodsThirteenICClesionsin13patientswereevaluatedusingCEUS1CEUSwasperformedwithlowmechanicalindex,contrastpulsesequencingtechniqueandthecontrastagentofSonoVue1ResultsInthearterialphase,allthe13lesionsexhibitedheterogeneousenhancement1Ninefoci(6912%)appearedashypoechoic,andirregularrim2likehyperechoicenhancementwasvisualizedattheperipheryportionin71Other4lesions(3018%)showedashyper(in1)orisoechoic(in3)1Intheportalphase,allthe13lesionspresentedasheterogeneoushypoe2choic1Amongthe13lesions,thehypoechoicareapresentedenlargedin6(4612%)1Inthelatephase,allthelesionsexhibitedhomogeneoushypoechogenicity1ConclusionsTheenhancementofICChascharacteristic,whichmaybehelpfulforthecharacterizationofthisentity1Keywords:Intrahepaticcholangiocarcinoma,Contrast2enhancedultrasound,Enhancementfeature.(intrahepaticcholangiocarcinoma,ICC)[122],(me2chanicalindex,MI)(contras2tenhancedultrasound,CEUS),(focalliverlesion,FLL)13ICC:2004320051,13ICCCEUS9,44068,(588):(No.2002C31108):510080,(),()11,2113317918cm,(715211)cm:AcusonSequoia512()4V1,110410MHz(contrastpulsesequencing,CPS):SonoVue(Bracco),5ml,,(SF6)214ml,,5mlCEUS:CPS,MI012,6min,4922006224ChineseJUltrasoundMedVol22No42006:(830s)(31120s)(121360s)3,13ICC4,92(1514%),,511cm917cm11(8416%),7(5318%)(n=1)(n=6)2(1514%)4(3018%)4(3018%),1(717%)6(4612%)2,11138,239(6912%)(1),7,(2):27s()8;:93s(),1CEUS:14s()4,()():44s(),()2CEUS4(3018%)(n=1)(n=3)74,6(4612%)(2),ICC,,,[3]ICCCTMRI,ICCCT,ICCCT,39min,,MRICTMICEUS5922006224ChineseJUltrasoundMedVol22No42006CTMRIICCCEUSICC,MILevovist,Celik[4]26FLL1ICC,vonHerbay[5]MI126FLL1ICC,,Quaia[6]MI452FLL,1ICCTonolini[2]MIICC,1313ICC,9,4CTMRICEUSICC,,[3],,,ICCCTMRI,CEUS[7],13ICC11,,ICCCEUSICCCEUSCTMRI,ICC,CTMRI,,ICCCEUS:,,,,[1]KhanSA,DavidsonBR,GoldinR,etal.Guidelinesforthediag2nosisandtreatmentofcholangiocarcinoma:consensusdocument.Gut,2002,51(SupplVI):vi12vi9.[2]TonoliniM,CovaL,OstiV,etal.Othermalignancies.InSolbiatietal.Contrast2enhancedultrasoundofliverdiseases.SpringerVerlag,2003,89293.[3]HanJK,ChoiBI,KimAY,etal.Cholangiocarcinoma:pictorialessayofCTandcholangiographicfindings.RadioGraphics,2002,22:1732187.[4]CelikH,OzdemirH,YcelC,etal.Characterizationofhypere2choicfocalliverlesions:quantitativeevaluationwithpulseinver2sionharmonicimaginginthelatephaseoflevovist.JUltrasoundMed,2005,24:39247.[5]VonHerbayA,VogtC,WillersR,etal.Real2timeimagingwiththesonographiccontrastagentSonoVuedifferentiationbetweenbenignandmalignanthepaticlesions.JUltrasoundMed,2004,23:155721568.[6]QuaiaE,CalliadaF,BertolottoM,etal.Characterizationoffocalliverlesionswithcontrast2specificUSmodesandasulfurhex2afluoride2filledmicrobubblecontrastagent:diagnosticperfor2manceandconfidence.Radiology,2004,232:4202430.[7],,,..,2004,24:6692671.(2005210211,186)GBöT158352199511,5%10%,510%,01050110,50110;21,6017%014%,(6017014)%,,6017014%,6017%014;31,7cm5cm3cm,753(cm),753cm3,105cm3,,,,,20062022266922006224ChineseJUltrasoundMedVol22No42006