基于PPG的心率和呼吸频率的测量研究-马俊领

37320115　　　　　　　　　　　　　　　OPTICALTECHNIQUE　　　　　　　　　　　　　　　Vol.37No.3May2011　　:1002-1582(2011)03-0309-04基于PPG的心率和呼吸频率的测量研究＊马俊领,王成,李章俊,赵宏垚(,200093)　:(PhotoPlethysmoGraphy,PPG)、。PPG,PPG,。。、、,。:;;;;:TP274+.2　　　:AStudyofmeasuringheartrateandrespirationratebasedonPPGMAJunling,WANGCheng,LIZhangjun,ZHAOHongyao(SchoolofMedicalInstrumentandFoodEngineering,UniversityofShanghaiforScienceandTechnology,Shanghai200093,China)Abstract:PhotoPlethysmoGraphy(PPG)isusedtomeasurethehumanphysiologicalparametersbecauseitissimple,stableandstrongadaptability.ThehumanheartrateandrespirationrateisdetectedinfrequencydomainofthePPGsig-nalwhichiscomputedbyFouriertransform.ThePPGsignaloftheradialarteryisobtainedbasedonreflectingphotoelec-tricmodeestablished.ThecorrespondingdateofheartandrespirationratesobtainedbyFastFouriertransformofPPGgoodagreewiththeresultsdetectedbymedicalmonitor.ThemethodofFastFouriertransformcanrealizetomeasurehu-manheartandrespirationratesquicklyandaccurately.Aportabledevicecanbemadebythismethodandcanbeusedinhospitalordailylifecare.Keywords:biologicaloptics;PPG;FFT;heartrate;respirationrate0　　,[1]。。,。。;。,。,309＊:2010-10-20;:2010-12-30　　　E-mail:[e-mail];[e-mail]:(2007CG62):(1985-),,,。:(1977-),,,,。。1981,NijboerPPG、[2]。PPG,PPG:、、[3]。,,,,,PPG[4,5]。,PPG,PPG。PPG、。Nilsson0.1Hz～0.3Hz(6/min～18/min)PPG,0.5/min[6,7]。AddisonMor-letPPG,1/min,[8]。Yue-DerLinPPG,1.2/min[9]。FlemingPPG,0.04/min[10]。PPG。、。Lambert-Beer,,:,,;,。2FFT,,PPG。Matlab,PPG,。1　PPG1.1　PPG:660nmLED,3DU5B。LED,12mm。,,LED,LED,。,,,[11]。,,,[12]。:,LED,。1.2　PPG,LED,PPG,PPG,LED。,,,PPG。0.2Hz～0.3Hz(12/min～20/min),,0.06Hz～0.7Hz(4/min～42/min);1Hz～1.6Hz(60/min～100/min),,,0.05Hz～3Hz(3/min～180/min),,50Hz。1。1　2　2.1　PPG10PPG,Labview,PCI-9111DRPPG,。PPG:5min,,2min,310　　　　　　　　　　　　　　　　　　　　　　　　　　　　　　　　　　　　　　　　　372min,,10,3。PPG,2min,2min。,PPG,,。2.2　PPG(FastFourierTransform,FFT)PPG。(DiscreteFourierTransform,DFT):NN2,2FFTN2log2N,[13]。,,PPG。,Matlab,,PPG。2.3PPGMatlab,,1024,MatlabPPGFFT,23PPG。2　PPG3　2PPG,3PPGFFT,,。PPG0.3Hz(18/min)1.2Hz(72/min),。PPG,。,3,3。1。　　　　1　:/min173±1.215±1.573±1.114±1.0275±1.118±1.076±0.918±0.8378±1.315±0.878±0.615±0.9472±1.518±1.072±1.218±1.3571±1.016±1.271±1.016±0.7672±1.314±1.372±0.515±0.8774±1.115±1.074±0.915±0.7877±1.217±0.877±0.817±0.9976±1.015±1.176±1.015±0.61075±1.416±0.875±0.816±0.73　　1,1。EXCEL:r=0.991,r=0.940,,PPG。PPG,、、,、、。1W,5cm×4cm×2cm,,53g。,10s,,。3113,:　PPG,,。、、,。:[1],.[M].:,1983:176—183.ZhouYJ,ZhangJR.Physiology[M].Beijing:People'sMedi-calPublishingHouse,1983:176—183.[2]NijboerJA,DorlasJC,MahieuHF.Photoelectricplethysmo-graphy-somefundamentalaspectsofthereflectionandtransmis-sionmethods[J].ClinicalPhysicsandPhysiologicalMeasure-ment,1981,2:205—215.[3]BernardiL.,RadaelliA.,Solda′PL.Autonomiccontrolofskinmicrovessels:assessmentbypowerspectrumofphotople-thysmographicwaves[J].ClinicScience,1996,90:345—355.[4]AndersJohansson,Per゜Ake¨Oberg,GunnarSedin.Monitoringofheartandrespiratoryratesinnewborninfantsusinganewphotoplethysmographictechnique[J].JournalofClinicalMoni-toringandComputing,1999,15:461—467.[5]NilssonL,JohanssonA,KalmanS.Monitoringofrespiratoryrateinpostoperativecareusinganewphotoplethysmographictechnique[J].JournalofClinicalMonitoringandComputing,2000,16:309—315.[6]NilssonL,JohanssonA,KalmanS.Respirationcanbemoni-toredbyphotoplethysmographywithhighsensitivityandspeci-ficityregardlessofanaesthesiaandventilatorymode[J].ActaAnaesthesiologicaScandinavica,2005,49(8):1157—1162.[7]NilssonL,GoscinskiT,JohanssonA.Ageandgenderdonotinfluencetheabilitytodetectrespirationbyphotoplethysmogra-phy[J].JournalofClinicalMonitoringandComputing,2006,20(6):431—436.[8]CliftonD,DouglasJG,AddisonPS.Measurementofrespira-toryratefromthephotoplethysmograminchestclinicpatients[J].JournalofClinicalMonitoringandComputing,2007,21(1):55—61.[9]LinYD,LiuWT,TsaiCC.CoherenceAnalysisbetweenRes-pirationandPPGSignalbyBivariateARModel[J].Engineer-ingandTechnology,2009,53:847—852.[10]FlemingSG,TarassenkoL.Acomparisonofsignalprocessingtechniquesfortheextractionofbreathingratefromthephotopl-ethysmogram[J].InternationalJournalofBiomedicalSciences,2007,2(4):232—236.[11].[M].:,2008:122—124.DingGF.Humananatomy[M].Beijing:People'sMedicalPublishingHouse,2008:122—124.[12],,.[M].:,2006:11—13.LuoZC,ZhangS,YangYM.Engineeringanalysisandclini-calapplicationofthepulsewave[M].Beijing:SciencePress,2006:11—13.[13].[M].:,2005:529—555.HuGS.Digitalsignalprocessing[M].Beijing:TsinghuaUni-versityPress,2005:529—555.312　　　　　　　　　　　　　　　　　　　　　　　　　　　　　　　　　　　　　　　　　37