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3X(,550004)[]::69,-:27148h,91143%,-14127;36144h,82135%,-9103:-,[];;;,;[]R57312;R575121[]A[]100022707(2004)0620512203Cost2effectivenessAnalysisofTwoPharmacotherapeuticSchemesforHemorrhageofUpperDigestiveTractCausedbyLiverCirrhosisZHANGQuan(DepartmentofInfectiousDisease,GuiyangMedicalCollege,Guiyang55004,China)[Abstract]Objective:Toevaluatetheeffectivenessandcostsoftwopharmacotherapeuticschemesforhem2orrhageofupperdigestivetractcausedbylivercirrhosis.Methods:69patientsweredividedintosandostaintreatinggroupandpituitarinumposteriustreatinggrouprandomly.Evaluationwascarriedoutwithpharama2coeconomiccost2effectivenessanlysis.Results:Theeffectiveratewithsandostainwas91143%inameanof27148hours,whilethatwithpituitarinumposteriuswas82135%inameanof36144hours.Thecost2effec2tivenessofsandostaintherapyandpituitarinumposteriustherapywere14127and9103,respectively.Con2clusion:Accordingtotheevaluationwithpharmacoeconomiccost2effectivenessanalysis,thetherapeuticschemeofpituitarinumposteriusseemstobethebetteronefortreatinghemorrhageofdigestivetractresultedfromlivercirrhosis.[Keywords]pepticulcerhemorhage;livercirrhosis;sandostain;pituitaryhormones,posteriur;cost2costanalysis,,25%[1]30%70%,,,,69,-,11.120001220021169,2000()10,5269,215296200412JOURNALOFGUIYANGMEDICALCOLLEGEVol.29No.62004112X3[2],(1)1.2100g,25g/h()2448h0.4U/min,0.2U/min4872h:(200ml+8mg+1000U);80mg,1(40mg0115g,2/d),(),,1Tab11Acomparisonofbasicdataintwogroupsofpatientswithbleedingofupperdigestivetractcausedbylivercirrhosis.n()2040406060352114914121413834231115118121481.3:24h;:2472h:72h1.4-,21.5t222.1291143%,82135%,(P0105);8157%,17165%,(P0.05)18128%,10136%,6,269Tab12Thecurativeeffectsof69caseswithupperdigestivetractbleedingcausedbylivercirrhosisn(h)(%)(%)(%)3527.4816.31(1)48.57(2)42186(1)8.57(1)3436.4418.68(1)32.35(2)50.00(1)17.65(1),(1)P0.05,(2)P010052.2--14127,9103,32.32,,100%48h100%142217,90217,332-Tab13Acomparisonofeffectandexpensebetweenthetwotherapeuticschemesn()(%)-100%()3501160/g1300.82653.2291.4314.231422.73401283/U743.38381.0882.359.03902.72.41,A8,43103%35129%,3,,,(),31567611%,[3]24%41%,1/3(19%40%)[4],815%[6],,,Bosch[7]17110g/kg,1915mmHg14mmHg;715g/min17%,1715%,,8,,1115h,,,,[8],27148h(36144h),,,,,,,1,,3,1300182743138;-141279103,-,,,100%,2,,,-,,,4[1].[M].:,1985:576.[2].[J].,2000,8(6):324-329.[3],,,.[J].,2000,8(5):310-312.[4].[M].:,2000.435.[5],.[M].:,1999.403-404.[6].[J].,1995,15(1):1-3.[7]BoschJ.Effectsofsomatostatinonhepticandsystemichemo2dynamicsinpatientswithcirrhosisoftheliver,comparisonwithvasopressin[J].Gastroenterliligy,1981,80(6):518-522.[8]BurroghsAK,ColloJP.Somatostatinandoctreotideforvaricealbleeding[J].JHepatology,1991,13(1):2-9.(2004207215,2004208216)41529