AIDSByWeiWei,ZhouYuting,LiLisha,GuanXingya1.ConceptAcquiredimmunedeficiency([di'fiʃənsi])syndrome(['sindrəum])(获得性免疫缺陷综合症)oracquiredimmunodeficiency([i'mju:nəudi'fiʃənsi])syndrome(AIDS)isadiseaseofthehumanimmunesystemcausedbythehumanimmunodeficiencyvirus(HIV)(人类免疫不全病毒).Itistransmittedthroughdirectcontactofamucousmembrane(['mju:kəs]['membrein]粘膜)orthebloodstream(血液流动)withabodilyfluidcontainingHIV,suchasblood,semen,vaginalfluid,preseminalfluid,andbreastmilk.2.HISTORYGeneticresearchindicatesthatHIVoriginatedinwest-centralAfricaduringthelatenineteenthorearlytwentiethcentury.AIDSwasfirstrecognizedbytheU.S.CentersforDiseaseControlandPreventionin1981anditscause,HIV,identifiedintheearly1980s.AIDSisnowapandemic.3.CAUSEa)SexualtransmissionThemajorityofHIVinfectionsareacquiredthroughunprotectedsexualrelationsbetweenpartners,oneofwhomhasHIV.TheprimarymodeofHIVinfectionworldwideisthroughsexualcontactbetweenmembersoftheoppositesex.b)Exposuretoblood-bornepathogens(['pæθədʒən]病原体)Thistransmissionrouteisparticularlyrelevanttointravenous(['intrə'vi:nəs]静脉)drugusers,hemophiliacs([,hi:mə'filiæk])andrecipients([ri'sipiənt])ofbloodtransfusionsandbloodproducts.SharingandreusingsyringescontaminatedwithHIV-infectedbloodrepresentsamajorriskforinfectionwithHIV.c)Perinatal([,peri'neitəl]产期的)transmissionThetransmissionofthevirusfromthemothertothechildcanoccurinutero(子宫)duringthelastweeksofpregnancyandatchildbirth.4.SymptomsThesymptomsofAIDSareprimarilytheresultofconditionsthatdonotnormallydevelopinindividualswithhealthyimmunesystems.OpportunisticinfectionsarecommoninpeoplewithAIDS.Theseinfectionsaffectnearlyeveryorgansystem.PeoplewithAIDSalsohaveanincreasedriskofdevelopingvariouscancerssuchasKaposi'ssarcoma([sɑ:'kəumə]特发性出血性肉瘤),cervical(['sə:vikəl]颈部的)cancerandcancersoftheimmunesystemknownaslymphomas([lim'fəumə]淋巴瘤).Additionally,peoplewithAIDSoftenhavesystemicsymptomsofinfectionlikefevers,sweats(particularlyatnight),swollenglands([glænd]),chills,weakness,andweightloss.5.Preventiona)Becarefulaboutyoursexualcontact.b)HIV-infectedmothersshouldavoidbreast-feedingtheirinfant.c)HealthcareworkerscanreduceexposuretoHIVbyemployingprecautions(预防措施)toreducetheriskofexposuretocontaminated([kən'tæmineitid]受感染的)blood.d)Themostimportantwaytochangeriskybehaviorishealtheducation.6.TreatmentAlthoughtreatmentsforAIDSandHIVcanslowthecourseofthedisease,thereiscurrentlynovaccineorcure.Antiretroviral(抗逆转录病毒的)treatmentreducesboththemortality([mɔ:'tæliti]死亡率)andthemorbidity([mɔ:'biditi]发病率),butthesedrugsareexpensiveandroutineaccesstoantiretroviralmedicationisnotavailableinallcountries.7.CurrentSituationIn2007,itwasestimatedthat33.2millionpeoplelivedwiththediseaseworldwide,andthatAIDSkilledanestimated2.1millionpeople,including330,000children.Overthree-quartersofthesedeathsoccurredinsub-SaharanAfrica,retarding([ri'tɑ:d]减缓)economicgrowthanddestroyinghumancapital.Thanks!