基于生物相容性材料的3D打印骨骼修复技术的研究与应用

45320173CHINAPLASTICSINDUSTＲY3D*523808。3D3D。3D。3D。3Ddoi10.3969/j.issn.1005－5770.2017.03.029TQ320.72B1005－5770201703－0165－03ＲesearchandApplicationofthe3-DPrintingBoneＲepairTechnologyBasedonBiocompatibilityMaterialCHENSheng-guiSUNZhen-zhongSchoolofMechanicalEngineeringDongguanUniversityofTechnologyDongguan523808ChinaAbstractThebonerepairsurgeryisakindofhighdifficultysurgeryandthekeystosuccessofthesurgeryaretheselectionandformingstructureofbone-repairingmaterials．Withthree-dimensional3-Dprintingtechnologyusedwidelyinclinicalmedicineandbasedonthebiocompatibilitymaterialthemedicalcostandthefailurerateforrepairsurgeryreducedgraduallybythe3-Dprintingbone-repairingtechnology．The3-Dprintingbiocompatibilitymaterialsinapplicationofthebone-repairsurgerywereclassified．Ｒespectivelythepolymermaterialsandceramicmaterialsinthefieldofresearchandapplicationwereintroduced．Finallythedevelopmenttrendandfar-reachingsignificanceof3-Dprintingbiocompatibilitymaterialsinbone-repairwerementioned．KeywordsBiocompatibilityThree-dimensionalPrintingBoneＲepairSurgery、。。。3D。3D、、。。3D。13D。。·561·*2014、20141061010091984/3D、、。20171.13D。3DPGA、PLA、PCL—PLGA。3DPLACO21。PLA、。3DPLA。PCLC—OC—C。PCL。PCL。TCPPCLTCPPCL3D。13DPCL。13DPCLFig13-DprintingPCLbonescaffoldCai2PCL。Lam3PCL。PCL。3D。。Tetsu4PLA。53D－。。、、。6。。。。3D。1.2。、、。18·661·4533D。3D3D。、3D、、。、。、/β－。3D。β－/β－。3D。3D7。3D/β－3D。8β－β－β－3D3D。3D9SLA、SLS、FDM、LOM3D3DSLSFDM。23D3D。12、3。3D。3D。103D3D。OPMPEKK3D75%。CT3D。3D。3D。33D。。3D。3D。137·761·4532、。3。4、。4。、、、、、、、、、、、。1．M．1989．2．M．2014．3．J．200214135－37．2016－11－161671．3DJ．20136722－732．2CAIYLLIJLPOHCKetal．Collagengrafted3DpolycaprolactonescaffoldsforenhancedcartilageregenerationJ．JMaterChemB20134315971－5976．3LAMCXFMOXMTEOHSHetal．Scaffolddevelop-mentusing3Dprintingwithastarch-basedpolymerJ．MaterSciEngC200220249－56．4TETSUMSFEＲＲYPWMJANFJeta1．Designedbiodegradablehydrogelstructurespreparedbystereolithographyusingpolyethyleneglycol/polyDL-lactide-basedresinsJ．JControlledＲelease2010148134－41．5．3-D－J．20152981022－1027．6．D．2014．7INZANAJAOLVEＲADFULLEＲSMetal．3DprintingofcompositecalciumphosphateandcollagenscaffoldsforboneregenerationJ．Biomaterials201435134026－4027．8．J．201418436914－6921．9．ＲPMJ．20023516－8．10．3DD．2014．2017－01－06ABSIneosStyrolutionABS。FleimaPlastic。FleimaPlastic。ABSFleimaPlastic。。“ABSe、、。”FleimaPlasticIsmailDogru。NovodurHDM203FCG3ISO10993USPClassVI。FleimaPlastic、。。“NovodurHDM203FCG3。”。·731·