欧洲风湿病防治联合会(EuropeanLeagueAgainstRheumatism,EULAR)推荐的RA疾病活动性评分系统(diseaseactivityscorein28joints,DAS28)=0.56×TJC(包括肩、肘、腕、掌指关节、近端指间关节、膝关节在内的28个压痛关节计数,thenumberoftenderjointsof28counted)+0.28×SJC(肿胀关节计数,thenumberofswollenjointsof28counted)+0.7×In(血沉,erythrocytesedimentationrate,ESR)+0.014×VAS(受试者评估的疼痛用100mm目测模拟标尺,visualanaloguescale),病情稳定为2.6分;低活动度为2.6-3.2分;中度活动度为3.2-5.1分;高度活动为5.1[19]。19PrevooML,van'tHofMA,KuperHH,etal.Modifieddiseaseactivityscoresthatincludetwenty-eight-jointcounts.Developmentandvalidationinaprospectivelongitudinalstudyofpatientswithrheumatoidarthritis[J].ArthritisRheum,1995;38:44-48.DAS28(CRP)=0.56*(TJC28)1/2+0.28*(SJC28)1/2+0.014*GH+0.36*ln(CRP+1)+0.96;DAS28(ESR)=0.56*(TJC28)1/2+0.28*(SJC28)1/2+0.014*GH+0.70*ln(ESR)WellsG,BeckerJC,TengJ,et,al.Validationofthe28-jointDiseaseActivityScore(DAS28)andEuropeanLeagueAgainstRheumatismresponsecriteriabasedonC-reactiveproteinagainstdiseaseprogressioninpatientswithrheumatoidarthritis,andcomparisonwiththeDAS28basedonerythrocytesedimentationrate.AnnRheumDis2009;68:954–960.